{Reference Type}: Review
{Title}: Impetigo herpetiformis in the second trimester: a case report and review of the literature.
{Author}: Wan Y;Zhang L;Xie B;Wu J;Zhao M;Guo J;Ding J;
{Journal}: J Int Med Res
{Volume}: 51
{Issue}: 12
{Year}: 2023 Dec
{Factor}: 1.573
{DOI}: 10.1177/03000605231217950
{Abstract}: Impetigo herpetiformis is a rare skin disease that most often occurs in the third trimester of pregnancy. It is currently considered as a form of generalized pustular psoriasis and the typical skin lesions comprise small sterile pustules. Here, a case of impetigo herpetiformis in the second trimester of pregnancy after 7 weeks of hydroxychloroquine administration for suspected Sjogren's syndrome is reported. Treatment with anti-infective, anti-inflammatory and immunosuppressive medication did not improve the patient's condition. Following delivery of a live male by emergency caesarean section at 29 weeks' gestation, the rash was reported to be completely resolved by 3 months postpartum. Previously published cases of impetigo herpetiformis in the second trimester of pregnancy that were retrieved from a search of the PubMed database are also reviewed and discussed.