%0 Review
%T Impetigo herpetiformis in the second trimester: a case report and review of the literature.
%A Wan Y
%A Zhang L
%A Xie B
%A Wu J
%A Zhao M
%A Guo J
%A Ding J
%J J Int Med Res
%V 51
%N 12
%D 2023 Dec
%M 38102997
%F 1.573
%R 10.1177/03000605231217950
%X Impetigo herpetiformis is a rare skin disease that most often occurs in the third trimester of pregnancy. It is currently considered as a form of generalized pustular psoriasis and the typical skin lesions comprise small sterile pustules. Here, a case of impetigo herpetiformis in the second trimester of pregnancy after 7 weeks of hydroxychloroquine administration for suspected Sjogren's syndrome is reported. Treatment with anti-infective, anti-inflammatory and immunosuppressive medication did not improve the patient's condition. Following delivery of a live male by emergency caesarean section at 29 weeks' gestation, the rash was reported to be completely resolved by 3 months postpartum. Previously published cases of impetigo herpetiformis in the second trimester of pregnancy that were retrieved from a search of the PubMed database are also reviewed and discussed.