Abstract：
UNASSIGNED: Merkel cell carcinoma of the eyelid (MCCE) is a rare yet aggressive neuroendocrine tumour associated with significant morbidity and mortality. This study aimed to investigate survival trends and demographic factors related to MCCE, 2000-2019, using the Surveillance, Epidemiology, and End Results (SEER) Program.
UNASSIGNED: Cases were analysed by demographic parameters, disease properties, and survival. Statistical analyses were performed via a dedicated computerized software package.
UNASSIGNED: A total 349 cases of MCCE were identified, accounting for 2% of all MCC cases in the United States during that time. Of note, the incidence of MCCE remained stable over the study period (p = .35). Female patients accounted for 56% of the cases, and males for 44%. White patients accounted for 90.8% of the the cases, and Black patients for 2.9%. MCCE incidence increased with age, with the majority of patients age 85+ (p < .05). Incidence was greatest in metropolitan areas and among those with median incomes >$75,000/year. Income correlated with likelihood of MCCE diagnosis (p < .05). Analysis of 5-year survival data showed 20% of the patients died due to MCCE within 5 years of diagnosis. Of these, the majority died within one year of diagnosis.
UNASSIGNED: Consistent with previous reports, most patients were white, female, and age 85+.Incidence correlated with metropolitan environments and median income. While most patients did not die from MCCE, majority of recorded deaths occurred within one year of diagnosis.
UNASSIGNED: Cases were analysed by demographic parameters, disease properties, and survival. Statistical analyses were performed via a dedicated computerized software package.
UNASSIGNED: A total 349 cases of MCCE were identified, accounting for 2% of all MCC cases in the United States during that time. Of note, the incidence of MCCE remained stable over the study period (p = .35). Female patients accounted for 56% of the cases, and males for 44%. White patients accounted for 90.8% of the the cases, and Black patients for 2.9%. MCCE incidence increased with age, with the majority of patients age 85+ (p < .05). Incidence was greatest in metropolitan areas and among those with median incomes >$75,000/year. Income correlated with likelihood of MCCE diagnosis (p < .05). Analysis of 5-year survival data showed 20% of the patients died due to MCCE within 5 years of diagnosis. Of these, the majority died within one year of diagnosis.
UNASSIGNED: Consistent with previous reports, most patients were white, female, and age 85+.Incidence correlated with metropolitan environments and median income. While most patients did not die from MCCE, majority of recorded deaths occurred within one year of diagnosis.
摘要：
■眼睑默克尔细胞癌（MCCE）是一种罕见但侵袭性的神经内分泌肿瘤，具有显著的发病率和死亡率。本研究旨在调查与MCCE相关的生存趋势和人口统计学因素。2000-2019年，使用监控，流行病学,和最终结果（SEER）计划。
■病例按人口统计参数进行分析，疾病属性，和生存。通过专用的计算机化软件包进行统计分析。
■共发现349例MCCE，在此期间，占美国所有MCC病例的2%。值得注意的是，MCCE的发生率在研究期间保持稳定(p=.35).女性患者占56%，男性占44%。白人患者占90.8%,黑人患者占2.9%。MCCE发病率随年龄增加,大多数患者年龄在85岁以上（p<0.05）。在大都市地区和平均收入>75,000美元/年的人群中，发病率最高。收入与MCCE诊断的可能性相关(p<0.05)。对5年生存数据的分析显示，20％的患者在诊断后5年内因MCCE死亡。其中,大多数人在诊断后一年内死亡。
■与以前的报告一致，大多数病人是白人,女性,年龄85+。发病率与大都市环境和收入中位数相关。虽然大多数患者没有死于MCCE，大多数记录的死亡发生在诊断后1年内.
■病例按人口统计参数进行分析，疾病属性，和生存。通过专用的计算机化软件包进行统计分析。
■共发现349例MCCE，在此期间，占美国所有MCC病例的2%。值得注意的是，MCCE的发生率在研究期间保持稳定(p=.35).女性患者占56%，男性占44%。白人患者占90.8%,黑人患者占2.9%。MCCE发病率随年龄增加,大多数患者年龄在85岁以上（p<0.05）。在大都市地区和平均收入>75,000美元/年的人群中，发病率最高。收入与MCCE诊断的可能性相关(p<0.05)。对5年生存数据的分析显示，20％的患者在诊断后5年内因MCCE死亡。其中,大多数人在诊断后一年内死亡。
■与以前的报告一致，大多数病人是白人,女性,年龄85+。发病率与大都市环境和收入中位数相关。虽然大多数患者没有死于MCCE，大多数记录的死亡发生在诊断后1年内.
