Abstract：
Mikania micrantha is utilized as a therapeutic for the treatment of various human ailments including insect bites, rashes and itches of skin, chicken pox, healing of sores and wounds, colds and fever, nausea, jaundice, rheumatism, and respiratory ailments. This study aimed at summarizing the traditional uses, phytochemical profile, and biological activities of M. micrantha based on obtainable information screened from different databases. An up-to-date search was performed on M. micrantha in PubMed, Science Direct, clinicaltrials.gov, and Google Scholar databases with specific keywords. No language restrictions were imposed. Published articles, theses, seminar/conference papers, abstracts, and books on ethnobotany, phytochemistry and pharmacological evidence were considered. Based on the inclusion criteria, this study includes 53 published records from the above-mentioned databases. The results suggest that fresh leaves and whole plant are frequently used in folk medicine. The plant contains more than 150 different phytochemicals under the following groups: essential oils, phenolics and flavonoids, terpenes, terpene lactones, glycosides, and sulfated flavonoids. It contains carbohydrates and micronutrients including vitamins and major and trace minerals. M. micrantha possesses antioxidant, anti-inflammatory, anti-microbial, anti-dermatophytic, anti-protozoal, anthelmintic, cytotoxic, anxiolytic, anti-diabetic, lipid-lowering and antidiabetic, spasmolytic, memory-enhancing, wound-healing, anti-aging, and thrombolytic activities. No clinical studies have been reported to date. M. micrantha might be one of the potential sources of phytotherapeutic compounds against diverse ailments in humans. Studies are required to confirm its safety profile in experimental animals prior to initiating clinical trials. Moreover, adequate investigation is also crucial to clarify exact mechanism of action for each biological effect.
摘要：
薇甘菊被用作治疗各种人类疾病的治疗剂，包括昆虫叮咬，皮疹和皮肤瘙痒，水痘,伤口和伤口愈合，感冒和发烧,恶心,黄疸,风湿病,和呼吸道疾病。本研究旨在总结传统用途，植物化学概况，根据从不同数据库中筛选的可获得的信息，以及薇甘菊的生物活性。结果表明，新鲜的叶子和整株植物在民间医学中经常使用。该植物含有以下组的150多种不同的植物化学物质：精油，酚类和类黄酮，萜烯,萜烯内酯,糖苷，和硫酸化的类黄酮.它含有碳水化合物和微量营养素，包括维生素和主要和微量矿物质。M.micrantha具有抗氧化剂，抗炎,抗微生物,抗皮肤癣菌，抗原生动物，驱虫药,细胞毒性，抗焦虑药,抗糖尿病，降脂和抗糖尿病，痉挛,增强记忆，伤口愈合,抗衰老,和溶栓活性。迄今为止，尚无临床研究报告。薇甘菊可能是针对人类多种疾病的植物治疗化合物的潜在来源之一。在开始临床试验之前，需要进行研究以确认其在实验动物中的安全性。此外，充分的调查对于阐明每种生物效应的确切作用机制也至关重要。
