Diagnostic Accuracy of Group A Streptococcus Rapid Antigen Detection Test on Middle Ear Fluid in Children With Acute Otitis Media With Spontaneous Perforation: A Prospective Multicenter Evaluation.

急性中耳炎自发性穿孔儿童中耳液 A 组链球菌快速抗原检测的诊断准确性 ： 前瞻性多中心评估。

• 影响指数: 3.806
• 发表时间: 2023 09 1
• 来源期刊: Pediatr Infect Dis J
• DOI: 10.1097/INF.0000000000004009
• PMID: 37368992
• 文章类型: Multicenter Study
• 中科院分区: Q4
• 方向: 医学
• 作者列表: Cohen R,Varon E,Bidet P,Cohen JF,Béchet S,Couloigner V,Michot AS,Guiheneuf C,Bonacorsi S,Levy C

Mesh: Child; Humans; Infant; Pneumococcal Infections / complications; Spontaneous Perforation / complications; Prospective Studies; Streptococcus pneumoniae; Otitis Media / complications; Streptococcus pyogenes; Ear, Middle; Otitis Media with Effusion / etiology

Abstract

Group A Streptococcus is one of the leading causes of otorrhea. The performance of rapid antigen tests in 256 children with otorrhea showed excellent sensitivity, 97.3% (95% confidence interval: 90.7%-99.7%), and specificity, 100% (95% confidence interval: 98.0%-100%). In a period of increasing invasive and noninvasive group A Streptococcus infections, an early diagnosis could be useful.

摘要

A组链球菌是耳漏的主要原因之一。256例耳漏患儿的快速抗原检测表现出极好的敏感性,97.3%（95%置信区间：90.7%-99.7%），和特异性，100%(95%置信区间:98.0%-100%)。在侵袭性和非侵袭性A组链球菌感染增加的时期，早期诊断可能是有用的。