%0 Multicenter Study %T Diagnostic Accuracy of Group A Streptococcus Rapid Antigen Detection Test on Middle Ear Fluid in Children With Acute Otitis Media With Spontaneous Perforation: A Prospective Multicenter Evaluation. %A Cohen R %A Varon E %A Bidet P %A Cohen JF %A Béchet S %A Couloigner V %A Michot AS %A Guiheneuf C %A Bonacorsi S %A Levy C %J Pediatr Infect Dis J %V 42 %N 9 %D 2023 09 1 %M 37368992 %F 3.806 %R 10.1097/INF.0000000000004009 %X Group A Streptococcus is one of the leading causes of otorrhea. The performance of rapid antigen tests in 256 children with otorrhea showed excellent sensitivity, 97.3% (95% confidence interval: 90.7%-99.7%), and specificity, 100% (95% confidence interval: 98.0%-100%). In a period of increasing invasive and noninvasive group A Streptococcus infections, an early diagnosis could be useful.