{Reference Type}: Multicenter Study {Title}: Diagnostic Accuracy of Group A Streptococcus Rapid Antigen Detection Test on Middle Ear Fluid in Children With Acute Otitis Media With Spontaneous Perforation: A Prospective Multicenter Evaluation. {Author}: Cohen R;Varon E;Bidet P;Cohen JF;Béchet S;Couloigner V;Michot AS;Guiheneuf C;Bonacorsi S;Levy C; {Journal}: Pediatr Infect Dis J {Volume}: 42 {Issue}: 9 {Year}: 2023 09 1 {Factor}: 3.806 {DOI}: 10.1097/INF.0000000000004009 {Abstract}: Group A Streptococcus is one of the leading causes of otorrhea. The performance of rapid antigen tests in 256 children with otorrhea showed excellent sensitivity, 97.3% (95% confidence interval: 90.7%-99.7%), and specificity, 100% (95% confidence interval: 98.0%-100%). In a period of increasing invasive and noninvasive group A Streptococcus infections, an early diagnosis could be useful.