Abstract：
Regeneration abilities are widespread among animals and select species can restore any body parts removed by wounds that sever the major body axes. This capability of whole-body regeneration as exemplified in flatworm planarians, Acoels, and Cnidarians involves initial responses to injury, the assessment of wound site polarization, determination of missing tissue and programming of blastema fate, and patterned outgrowth to restore axis content and proportionality. Wnt signaling drives many shared and conserved aspects of the biology of whole-body regeneration in the planarian species Schmidtea mediterranea and Dugesia japonica, in the Acoel Hofstenia miamia, and in Cnidarians Hydra and Nematostella. These overlapping mechanisms suggest whole-body regeneration might be an ancestral property across diverse animal taxa.
摘要：
再生能力在动物中很普遍，选定的物种可以恢复因切断主要身体轴的伤口而去除的任何身体部位。这种全身再生的能力，例如扁虫涡虫，Acoels,Cnidarians涉及对伤害的最初反应，伤口部位极化的评估，缺失组织的确定和胚芽命运的编程，和图案化的生长以恢复轴的含量和比例。Wnt信号驱动了涡虫物种Schmidteamediterranea和Dugesiajaponica的全身再生生物学的许多共享和保守的方面，在AcoelHofstenia迈阿密，还有Cnidarians九头蛇和Nematostella.这些重叠的机制表明，全身再生可能是各种动物类群的祖先特性。
