稳定钙配方对大鼠的体外遗传毒性评估和 28 天重复剂量口服毒性研究。
关键词: 28-day repeated dose oral toxicity ALK. Phos., alkaline phosphatase ALT, alanine aminotransferase APTT, activated partial thromboplastin time AST, aspartate aminotransferase BUN, blood urea nitrogen CHO, Chinese hamster ovary CPK, creatine phosphate kinase Chromosomal aberrations Clastogenicity Functional food mixture Genotoxicity LDH, lactate dehydrogenase MCH, mean corpuscular hemoglobin MCHC, mean corpuscular hemoglobin concentration MCV, mean corpuscular volume MOS, margin of safety MPV, mean platelet volume NOAEL, no observed adverse effect level OECD, organization for economic cooperation and development PT, prothrombin time RBC, red blood cell RDW, red blood cell volume distribution width SCF, steady-calcium formula TFDA, Taiwan food and drug administration WBC, white blood cell γ-GT, gamma glutamyl transpeptidase
来 源:
DOI:10.1016/j.toxrep.2022.04.008
PDF(Pubmed)