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Abstract：
On February 2, 2020, the head of a visually impaired school notified similar eye symptoms among the students. We investigated the cluster to confirm the diagnosis, identify potential exposures, and propose recommendations.
We defined a case as redness/watering/discharge from any eye among the students and staff, January-February 2020. We actively searched for the cases and calculated attack rates. We drew epicurve by date of symptoms onset. We conducted a retrospective cohort study of students and staff. We collected data on potential exposures and calculated Risk Ratio (RR), 95% Confidence Interval (95%CI), and Population Attributable Risk (PAR). We sent a conjunctival swab of the three cases for microbiological analysis.
We diagnosed the cases as acute conjunctivitis and identified 39 (76%) cases among 51 individuals. All the 39 cases reported watering and redness; 28 (72%) and 12 (31%) reported eye pain and discharge, respectively. The median age of the case was 11 years (range: 6-48 years). The attack rate didn\'t differ significantly between males [77% (20/26)] and females [76% (19/25), p = 0.9]. The attack rate was higher among the students [86%, (38/44)] than staffs [14%, (1/7), p = <0.01]. Contact with a case [RR = 2.5, 95%CI = 1.3-4.8, PAR = 51%] and staying inside campus [RR = 6.0, 95%CI = 1.0-37.3, PAR = 81%] were associated with the acute conjunctivitis outbreak. All the three conjunctival swabs were negative for bacterial growth.
Close contact with the case and staying inside the campus led to the outbreak of acute conjunctivitis among the students and staff of the visually impaired school.
We defined a case as redness/watering/discharge from any eye among the students and staff, January-February 2020. We actively searched for the cases and calculated attack rates. We drew epicurve by date of symptoms onset. We conducted a retrospective cohort study of students and staff. We collected data on potential exposures and calculated Risk Ratio (RR), 95% Confidence Interval (95%CI), and Population Attributable Risk (PAR). We sent a conjunctival swab of the three cases for microbiological analysis.
We diagnosed the cases as acute conjunctivitis and identified 39 (76%) cases among 51 individuals. All the 39 cases reported watering and redness; 28 (72%) and 12 (31%) reported eye pain and discharge, respectively. The median age of the case was 11 years (range: 6-48 years). The attack rate didn\'t differ significantly between males [77% (20/26)] and females [76% (19/25), p = 0.9]. The attack rate was higher among the students [86%, (38/44)] than staffs [14%, (1/7), p = <0.01]. Contact with a case [RR = 2.5, 95%CI = 1.3-4.8, PAR = 51%] and staying inside campus [RR = 6.0, 95%CI = 1.0-37.3, PAR = 81%] were associated with the acute conjunctivitis outbreak. All the three conjunctival swabs were negative for bacterial growth.
Close contact with the case and staying inside the campus led to the outbreak of acute conjunctivitis among the students and staff of the visually impaired school.
摘要：
2020年2月2日，一所视障学校的负责人通知学生出现类似的眼部症状。我们调查了集群以确认诊断，识别潜在的暴露，并提出建议。
我们将案例定义为学生和教职员工中任何眼睛的发红/浇水/放电，2020年1月-2月。我们积极搜索案例并计算攻击率。我们根据症状出现的日期绘制了内表膜。我们对学生和教职员工进行了回顾性队列研究。我们收集了潜在风险暴露的数据，并计算了风险比(RR)，95%置信区间(95CI)，和人口归因风险(PAR)。我们发送了三例病例的结膜拭子进行微生物分析。
我们将这些病例诊断为急性结膜炎，并在51人中确定了39例（76％）病例。所有39例患者报告有水分和红肿；28例（72％）和12例（31％）报告有眼痛和放电，分别。病例的中位年龄为11岁（范围：6-48岁）。男性[77%(20/26)]和女性[76%(19/25)]的发病率没有显著差异，p=0.9]。学生的攻击率较高[86%，（38/44）]比员工[14%，（1/7）p=<0.01]。与病例接触[RR=2.5，95CI=1.3-4.8，PAR=51%]和留在校园内[RR=6.0，95CI=1.0-37.3，PAR=81%]与急性结膜炎爆发相关。所有三个结膜拭子均为细菌生长阴性。
与病例密切接触并留在校园内导致视障学校的学生和教职员工爆发急性结膜炎。
我们将案例定义为学生和教职员工中任何眼睛的发红/浇水/放电，2020年1月-2月。我们积极搜索案例并计算攻击率。我们根据症状出现的日期绘制了内表膜。我们对学生和教职员工进行了回顾性队列研究。我们收集了潜在风险暴露的数据，并计算了风险比(RR)，95%置信区间(95CI)，和人口归因风险(PAR)。我们发送了三例病例的结膜拭子进行微生物分析。
我们将这些病例诊断为急性结膜炎，并在51人中确定了39例（76％）病例。所有39例患者报告有水分和红肿；28例（72％）和12例（31％）报告有眼痛和放电，分别。病例的中位年龄为11岁（范围：6-48岁）。男性[77%(20/26)]和女性[76%(19/25)]的发病率没有显著差异，p=0.9]。学生的攻击率较高[86%，（38/44）]比员工[14%，（1/7）p=<0.01]。与病例接触[RR=2.5，95CI=1.3-4.8，PAR=51%]和留在校园内[RR=6.0，95CI=1.0-37.3，PAR=81%]与急性结膜炎爆发相关。所有三个结膜拭子均为细菌生长阴性。
与病例密切接触并留在校园内导致视障学校的学生和教职员工爆发急性结膜炎。
