Abstract:
The COVID-19 pandemic has been inflicted upon humanity by the SARS-CoV-2 virus, the latest insidious incarnation of the coronaviruses group. While in its wake intense scientific research has produced breakthrough vaccines and cures, there still exists an immediate need to further understand the origin, mechanobiology and biochemistry, and destiny of this virus so that future pandemics arising from similar coronaviruses may be contained more effectively. In this Perspective, we discuss the various evidential findings of virus propagation and connect them to respective underpinning cellular biomechanical states leading to corresponding manifestations of the viral activity. We further propose avenues to tackle the virus, including from a \"musical\" vantage point, and contain its relentless strides that are currently afflicting the global populace.
摘要:
SARS-CoV-2病毒对人类造成了COVID-19大流行,冠状病毒组的最新阴险化身。虽然随之而来的是激烈的科学研究已经产生了突破性的疫苗和治疗方法,仍然存在进一步了解起源的迫切需要,机械生物学和生物化学,以及这种病毒的命运,以便可以更有效地控制未来由类似冠状病毒引起的大流行。从这个角度来看,我们讨论了病毒繁殖的各种证据发现,并将它们与各自的基础细胞生物力学状态联系起来,从而导致病毒活动的相应表现。我们进一步提出了应对病毒的途径,包括从“音乐”的有利位置,并遏制目前困扰全球民众的不懈努力。