关键词: CTGF, connective tissue growth factor CaO2 Chemotherapy DOX, doxorubicin DSPE-PEG2000, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ECM, extracellular matrix EPR, enhanced permeability and retention FBS, fetal bovine serum HA, hyaluronic acid HAase, hyaluronidase HIF-1 HIF-1α, hypoxia-inducible factor 1α Hypoxia MCTS, multicellular tumor spheroids MS, monostearin MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide MnO2 NP, nanoparticle Nanoparticle OA, oleic acid P-gp, P-glycoprotein PDT, photodynamic therapy TEM, transmission electron microscopy TME, tumor microenvironment Transportation Tumor CTGF, connective tissue growth factor CaO2 Chemotherapy DOX, doxorubicin DSPE-PEG2000, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ECM, extracellular matrix EPR, enhanced permeability and retention FBS, fetal bovine serum HA, hyaluronic acid HAase, hyaluronidase HIF-1 HIF-1α, hypoxia-inducible factor 1α Hypoxia MCTS, multicellular tumor spheroids MS, monostearin MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide MnO2 NP, nanoparticle Nanoparticle OA, oleic acid P-gp, P-glycoprotein PDT, photodynamic therapy TEM, transmission electron microscopy TME, tumor microenvironment Transportation Tumor
来 源:
DOI:10.1016/j.apsb.2021.04.021
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