关键词: Congenital defects labial adhesion labial minora fusion sexual function urinary function

Mesh : Adolescent Adult Child, Preschool Female Humans Infant Retrospective Studies Uterus Vulva Young Adult

来  源:   DOI:10.1080/15476278.2021.1905477   PDF(Sci-hub)   PDF(Pubmed)

Abstract:
Labial minora fusion persisting to the reproductive age is a rare type of labial fusion. Only 17 sporadic case-reports have been published to describe this disease. We report a retrospective cohort study of nine patients undergone surgical dissections in our hospital with labial minora fusion of reproductive age. General information, a medical history, gynecological examinations, preoperative ultrasonography and observations during surgery were reviewed. Four patients found vulva deformity at age 1.25 ± 1.09 years, and the remaining 5 patients discovered the disease when they reached child-bearing age (25.20 ± 4.31). The average age of operation was 22.89 ± 6.21 years. The characteristic symptoms of the disease were menstrual blood and urine excretion from the urethral orifice. No endometriosis was detected in all 9 patients. One patient was found to have congenital defects, with a double cervical and complete uterine septum. All patients recovered well without re-adhesion. Seven patients (7/9, 77.80%) were interviewed by telephone. Three patients had normal sexual life and all patients were able to control urination normally. This labial fusion was found in 44.44% patients shortly after birth and might combined with other defects, suggesting a congenital nature of the disease, and further indicates the developmental feature of the vulva.
摘要:
持续到生育年龄的阴唇小花融合是一种罕见的阴唇融合。仅发表了17份散发性病例报告来描述这种疾病。我们报告了一项回顾性队列研究,该研究是在我们医院接受手术解剖的9例育龄唇小融合患者。一般信息,病史,妇科检查,回顾了术前超声检查和手术过程中的观察。四名患者在1.25±1.09岁时发现外阴畸形,其余5例患者在达到育龄时发现了该疾病(25.20±4.31)。平均手术年龄为22.89±6.21岁。该病的特征性症状是经血和尿道口排泄的尿液。9例患者均未检出子宫内膜异位症。一名患者被发现有先天性缺陷,有双宫颈和完整的子宫隔膜。所有患者恢复良好,无再粘连。电话采访了7例患者(7/9,77.80%)。3例患者性生活正常,所有患者均能正常控制排尿。44.44%的患者在出生后不久就发现了这种唇融合,并且可能与其他缺陷相结合,表明这种疾病是先天性的,并进一步表明了外阴的发育特征。
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