线粒体自噬报告子小鼠分析显示在废用诱导的肌肉萎缩中增加的线粒体自噬活性。
关键词: ROS disuse-induced muscle atrophy hindlimb immobilization mitochondria mitophagy
Mesh : Adaptor Proteins, Signal Transducing / genetics metabolism Animals Disease Models, Animal Green Fluorescent Proteins / genetics metabolism Hindlimb Suspension Luminescent Proteins / genetics metabolism Membrane Proteins / genetics metabolism Mice, Inbred C57BL Mice, Transgenic Mitochondria, Heart / genetics metabolism pathology Mitochondria, Muscle / genetics metabolism pathology Mitophagy Muscle, Skeletal / metabolism pathology Muscular Atrophy / genetics metabolism pathology Myocardium / metabolism pathology Reactive Oxygen Species / metabolism Signal Transduction Starvation Time Factors Red Fluorescent Protein Mice
来 源:
DOI:10.1002/jcp.30404
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