人类肠道共生拟杆菌的功能遗传学揭示了跨环境生长的代谢需求。
关键词: Bacteroides thetaiotaomicron bile salts polysaccharide utilization random barcode transposon-site sequencing
Mesh : Adaptation, Physiological Ammonium Compounds / metabolism Animals Anti-Bacterial Agents / metabolism Bacterial Proteins / genetics metabolism Bacteroides thetaiotaomicron / drug effects enzymology genetics growth & development Bile Acids and Salts / metabolism Databases, Genetic Diet Disaccharides / metabolism Drug Resistance, Bacterial / genetics Energy Metabolism / genetics Gastrointestinal Microbiome / drug effects genetics Gene Expression Regulation, Bacterial Glycoside Hydrolases / genetics metabolism Humans Intestines / microbiology Male Membrane Transport Proteins / genetics metabolism Mice, Inbred C57BL Mutation Substrate Specificity Tripartite Motif Proteins / genetics metabolism Mice
来 源:
DOI:10.1016/j.celrep.2021.108789
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