关键词: Molecular docking Piperazine SAR Sulfonamide Synthesis α-Amylase inhibition
Mesh : Diabetes Mellitus, Type 2 / drug therapy metabolism Dose-Response Relationship, Drug Enzyme Inhibitors / chemical synthesis chemistry pharmacology Humans Hypoglycemic Agents / chemical synthesis chemistry pharmacology Molecular Docking Simulation Molecular Structure Piperazine Piperazines / chemical synthesis chemistry pharmacology Structure-Activity Relationship Sulfonamides / chemical synthesis chemistry pharmacology alpha-Amylases / antagonists & inhibitors metabolism
来 源:
DOI:10.1016/j.ejmech.2017.10.028
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