关键词: TALEN Xenopus genomic editing metamorphosis ouro tail resorption targeted gene knockout

Mesh : Animals Anura / immunology physiology Autolysis Metamorphosis, Biological / immunology physiology Models, Biological Musculoskeletal Physiological Phenomena / immunology Phagocytosis Reptilian Proteins / metabolism physiology Species Specificity Tail / physiology Xenopus

来  源:   DOI:10.1515/bmc-2017-0022   PDF(Sci-hub)

Abstract:
Amphibian metamorphosis has historically attracted a good deal of scientific attention owing to its dramatic nature and easy observability. However, the genetic mechanisms of amphibian metamorphosis have not been thoroughly examined using modern techniques such as gene cloning, DNA sequencing, polymerase chain reaction or genomic editing. Here, we review the current state of knowledge regarding molecular mechanisms underlying tadpole tail resorption.
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