关键词: High-speed digital imaging Laryngeal cancer Laryngeal granuloma Laryngeal leukoplakia Laryngeal papilloma Reinke edema Vocal fold cyst Vocal fold nodule Vocal fold polyp

Mesh : Adult Aged Aged, 80 and over Biomechanical Phenomena Carcinoma / diagnostic imaging physiopathology Case-Control Studies Female Humans Image Interpretation, Computer-Assisted Kymography Laryngeal Neoplasms / diagnostic imaging physiopathology Leukoplakia / diagnostic imaging physiopathology Male Middle Aged Phonation Polyps / diagnostic imaging physiopathology Predictive Value of Tests Severity of Illness Index Stroboscopy Time Factors Vibration Video Recording Vocal Cords / diagnostic imaging physiopathology

来  源:   DOI:10.1016/j.jvoice.2015.04.016

Abstract:
OBJECTIVE: To quantify vibratory characteristics of various laryngeal disorders seen by high-speed digital imaging (HSDI).
METHODS: HSDI was performed on 78 patients with various laryngeal disorders (20 with polyp, 16 with carcinoma, 13 with leukoplakia, 6 with vocal fold nodule, and 33 with others) and 29 vocally healthy subjects. Obtained data were quantitatively evaluated by frame-by-frame analysis, laryngotopography, digital kymography, and glottal area waveform.
RESULTS: Overall, patients with laryngeal pathologies showed greater asymmetry in amplitude, mucosal wave and phase, smaller mucosal wave, and poorer glottal closure than vocally healthy subjects. Furthermore, disease-specific vibratory disturbances that generally agreed with the findings in the literature were quantified: comparing polyp with nodule, differences were noted in longitudinal phase difference, amplitude, and mucosal wave. In comparison with leukoplakia and cancer, nonvibrating area was more frequently noted in cancer.
CONCLUSIONS: The HSDI analysis of various voice disorders using multiple methods can help phonosurgeons to properly diagnose various laryngeal pathologies and to estimate the degree of their vocal disturbances.
摘要:
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