Vibration

振动
  • 文章类型: Journal Article
    雄性katydids使用stridulation通过他们的专业前爪摩擦在一起产生声音,通过持续或中断的文件扫描产生不同的音调和呼叫结构。有许多种类的直翅目仍未被描述,它们的声音信号是未知的。本研究旨在测量和量化机翼振动的力学,Pseudophyllinae新属的听觉系统的声音产生和声学特性,具有两个新物种的分类学描述。使用微扫描激光多普勒测振仪测量了雄性的呼叫行为和机翼力学,显微镜,和超声波敏感设备。通过μ-CT扫描和3D打印实验获得了耳声尖的共振特性,并采用数值模型对结果进行了验证。对声音记录和机翼振动的分析表明,右脚的条纹区域表现出相对较窄的频率响应,并在12至20kHz之间产生窄带呼叫。和大多数假茶树一样,只有正确的镜子被激活声音产生。发现所有物种的声学耳廓可提供从〜40-120kHz高达25dB的宽带增加的声学增益,峰值接近90kHz,与同伴蝙蝠的回声定位频率一致。新属,名为Satizabalusn.gen。,在这里是从现有的Gnathoclita属中衍生出来的新的多型属,基于来自一个描述的形态学和声学证据(S.sodalisn.梳子.)和两个新物种(S.jorgevargasin.sp.和S.豪卡n.sp.).与大多数Tettigoniidae不同,Satizabalus表现出一种特殊形式的性二态性,与雌性相比,雄性的头部和下颌骨大大扩大。我们建议Satizabalus与Trichotettix属有关,也在哥伦比亚的云雾森林中发现,而不是Gnathoclita.
    Stridulation is used by male katydids to produce sound via the rubbing together of their specialised forewings, either by sustained or interrupted sweeps of the file producing different tones and call structures. There are many species of Orthoptera that remain undescribed and their acoustic signals are unknown. This study aims to measure and quantify the mechanics of wing vibration, sound production and acoustic properties of the hearing system in a new genus of Pseudophyllinae with taxonomic descriptions of two new species. The calling behaviour and wing mechanics of males were measured using micro-scanning laser Doppler vibrometry, microscopy, and ultrasound sensitive equipment. The resonant properties of the acoustic pinnae of the ears were obtained via μ-CT scanning and 3D printed experimentation, and numerical modelling was used to validate the results. Analysis of sound recordings and wing vibrations revealed that the stridulatory areas of the right tegmen exhibit relatively narrow frequency responses and produce narrowband calls between 12 and 20 kHz. As in most Pseudophyllinae, only the right mirror is activated for sound production. The acoustic pinnae of all species were found to provide a broadband increased acoustic gain from ~40-120 kHz by up to 25 dB, peaking at almost 90 kHz which coincides with the echolocation frequency of sympatric bats. The new genus, named Satizabalus n. gen., is here derived as a new polytypic genus from the existing genus Gnathoclita, based on morphological and acoustic evidence from one described (S. sodalis n. comb.) and two new species (S. jorgevargasi n. sp. and S. hauca n. sp.). Unlike most Tettigoniidae, Satizabalus exhibits a particular form of sexual dimorphism whereby the heads and mandibles of the males are greatly enlarged compared to the females. We suggest that Satizabalus is related to the genus Trichotettix, also found in cloud forests in Colombia, and not to Gnathoclita.
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  • 文章类型: Journal Article
    生物制造利用改良的微生物系统可持续地生产用于农业的商业上重要的生物分子,能源,食物,材料,和制药行业。然而,需要解决与无损和高通量代谢物筛选相关的技术挑战,以充分释放合成生物学和可持续生物制造的潜力。
    这个观点概述了工业细胞菌株开发计划中使用的当前分析筛选工具,并引入了无标签振动光谱显微镜作为替代对比机制。
    我们概述了当前在设计的“测试”部分中使用的分析仪器,build,test,学习合成生物学的周期。然后,我们重点介绍了拉曼散射和红外吸收成像技术的最新进展,这提高了分子特异性和灵敏度。
    高分辨率化学成像方法的最新发展允许更大的吞吐量,而不影响图像对比度。我们提供了支持与微流体集成以在单细胞水平进行快速筛查所需的未来工作的路线图。
    对代谢物的净表达进行定量,可以鉴定具有导致生物分子产生增加的代谢途径的细胞,这对于提高产量和降低工业生物制造成本至关重要。振动显微镜仪器的技术进步将极大地有利于生物材料作为非破坏性细胞筛选的补充方法。
    UNASSIGNED: Biomanufacturing utilizes modified microbial systems to sustainably produce commercially important biomolecules for use in agricultural, energy, food, material, and pharmaceutical industries. However, technological challenges related to non-destructive and high-throughput metabolite screening need to be addressed to fully unlock the potential of synthetic biology and sustainable biomanufacturing.
    UNASSIGNED: This perspective outlines current analytical screening tools used in industrial cell strain development programs and introduces label-free vibrational spectro-microscopy as an alternative contrast mechanism.
    UNASSIGNED: We provide an overview of the analytical instrumentation currently used in the \"test\" portion of the design, build, test, and learn cycle of synthetic biology. We then highlight recent progress in Raman scattering and infrared absorption imaging techniques, which have enabled improved molecular specificity and sensitivity.
    UNASSIGNED: Recent developments in high-resolution chemical imaging methods allow for greater throughput without compromising the image contrast. We provide a roadmap of future work needed to support integration with microfluidics for rapid screening at the single-cell level.
    UNASSIGNED: Quantifying the net expression of metabolites allows for the identification of cells with metabolic pathways that result in increased biomolecule production, which is essential for improving the yield and reducing the cost of industrial biomanufacturing. Technological advancements in vibrational microscopy instrumentation will greatly benefit biofoundries as a complementary approach for non-destructive cell screening.
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  • 文章类型: Journal Article
    下腰痛(LBP)是导致劳动力流失的常见公共卫生问题。
    本研究旨在评估土耳其东南部城市驾驶员之间的LBP状况及其影响因素。
    这项横断面问卷调查研究是在323名驾驶员中进行的。采用卡方检验和logistic回归分析。
    驾驶员的平均年龄为41.7±11.5岁(最小:19,最大:70),83.9%的人已婚,都是男人.在59.4%的驾驶员中发现了LBP。在社会经济地位较差的驾驶员中,这一比例明显更高,对自己的生活不满意,患有慢性疾病,身体不活跃,有睡眠障碍,暴露在恶劣的路况下,长时间的振动,高身体-心理工作量,有LBP家族史(p<0.05)。年龄之间没有显著关联,教育水平,BMI与LBP(p>0.05)。
    土耳其对这一主题的研究有限。进一步的研究可以提高对这个问题的认识,并制定教育计划。
    UNASSIGNED: Low back pain (LBP) is a common public health problem resulting in workforce loss.
    UNASSIGNED: This study aims to evaluate the LBP status and its affecting factors among drivers in a city in southeast Turkey.
    UNASSIGNED: This cross-sectional questionnaire survey study was conducted among 323 drivers. The chi-square test and logistic regression analysis were used to analyze the data.
    UNASSIGNED: The mean age of the drivers was 41.7±11.5 years (min: 19, max: 70), and 83.9% were married, and all were men. LBP was found in 59.4% of drivers. It was significantly higher in drivers with poor socioeconomic status, dissatisfied with their life, having a chronic illness, physically inactive, having sleep disorders, exposed to bad road conditions, prolonged vibration, high physical- psychological workload, and a family history of LBP (p <  0.05). There was no significant association between age, education level, and BMI with LBP (p >  0.05).
    UNASSIGNED: There is limited study on this subject in Turkey. Further studies can raise awareness about this issue and create an educational plan.
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  • 文章类型: Journal Article
    暂无摘要。
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  • 文章类型: Journal Article
    触觉图像(TI)仍然是一个相当缺乏研究的现象,尽管近年来对这个话题的关注越来越多。这里,我们通过测量单脉冲经颅磁刺激(TMS)诱发的运动诱发电位(MEP),研究了TI对皮质脊髓兴奋性的影响.将TI的效果与触觉刺激(TS)和动觉运动想象(kMI)的效果进行了比较。22名参与者按随机分配的顺序执行了三项任务:想象手指敲击(kMI);体验中指(TS)的振动感觉;并在精神上再现振动感(TI)。MEP在kMI和TI期间均增加,KMI的增加更强。在TS期间未观察到MEP的统计学显著变化。已证明的kMI差异效应,关于皮质脊髓兴奋性的TI和TS对于设计基于图像和基于TS的脑机接口(BCI)具有实际意义,特别是那些旨在通过唤起感觉运动电路的可塑性变化来改善神经康复的。
    Tactile Imagery (TI) remains a fairly understudied phenomenon despite growing attention to this topic in recent years. Here, we investigated the effects of TI on corticospinal excitability by measuring motor evoked potentials (MEPs) induced by single-pulse transcranial magnetic stimulation (TMS). The effects of TI were compared with those of tactile stimulation (TS) and kinesthetic motor imagery (kMI). Twenty-two participants performed three tasks in randomly assigned order: imagine finger tapping (kMI); experience vibratory sensations in the middle finger (TS); and mentally reproduce the sensation of vibration (TI). MEPs increased during both kMI and TI, with a stronger increase for kMI. No statistically significant change in MEP was observed during TS. The demonstrated differential effects of kMI, TI and TS on corticospinal excitability have practical implications for devising the imagery-based and TS-based brain-computer interfaces (BCIs), particularly the ones intended to improve neurorehabilitation by evoking plasticity changes in sensorimotor circuitry.
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  • 文章类型: Journal Article
    通过进行二维实验研究,本文旨在加强对长期循环侧向荷载作用下墙体附近砂土对流运动机理的理解。实验测试是在带有透明前壁的矩形沙箱中进行的,通过它可以使用高分辨率数码相机记录沙粒运动的过程。使用高时间分辨PIV(粒子图像测速)系统处理图像。根据实验数据,这项工作(1)介绍了对流带中的砂流场;(2)提供了描述对流机理的手段;(3)提出了具有强烈砂土运动的区域的载荷条件与尺寸之间的关系;(4)阐述了砂土对流带内的砂流速度结构的相似性。
    By conducting a two-dimensional experimental study, this paper aims to enhance the understanding of the mechanism of sand convective motions in the vicinity of a wall subjected to long-term cyclic lateral loadings. The experimental tests were conducted in a rectangular sandbox with a transparent front-wall, through which the process of sand particle motions could be recorded by using a high-resolution digital camera. The images were processed with a high time-resolved PIV (Particle Image Velocimetry) system. Based on the experimental data, this work (1) presents the sand flow field in the convective zones; (2) provides means to describe the convection mechanism; (3) proposes the relationships between the loading conditions and dimensions of the region with intense sand movement; and (4) elaborates the similarity of the sand flow velocity structure within the sand convective zones.
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  • 文章类型: Journal Article
    本研究通过探索用于估计眼内压(IOP)的声振特性来解决当前眼压测量技术的局限性。监测青光眼的关键诊断参数-视力丧失的重要危险因素。利用活体猪眼球,我们研究了IOP与非线性振动传递函数比(NVTFR)之间的关系。通过应用不同的振动水平,并通过传递函数分析和单变量回归分析响应,我们发现NVTFR和IOP之间存在很强的负相关,皮尔逊相关系数为-0.8111,广义线性模型(GLM)回归的显著结果(p值<0.001)证明了这一点。这些发现表明NVTFR作为IOP变化的重要指标的潜力。我们的研究强调了使用振动声学特性的可行性,特别是NVTFR,测量IOP。虽然在体内应用需要进一步改进,这种方法为非侵入性和患者友好的IOP监测开辟了新的可能性,可能增强眼科诊断技术,并为该关键领域的未来研究和开发奠定基础。
    This study addresses the limitations of current tonometry techniques by exploring vibroacoustic properties for estimating intraocular pressure (IOP), a key diagnostic parameter for monitoring glaucoma-a significant risk factor for vision loss. Utilizing vivo porcine eyeballs, we investigated the relationship between IOP and the nonlinear vibration transfer function ratio (NVTFR). Through applying varying vibration levels and analyzing responses with transfer function analysis and univariate regression, we identified a strong negative correlation between NVTFR and IOP, evidenced by a Pearson correlation coefficient of -0.8111 and significant results from generalized linear model (GLM) regression (p-value < 0.001). These findings indicate the potential of NVTFR as a vital indicator of IOP changes. Our study highlights the feasibility of using vibroacoustic properties, specifically NVTFR, to measure IOP. While further refinement is necessary for in vivo application, this approach opens new possibilities for non-invasive and patient-friendly IOP monitoring, potentially enhancing ophthalmology diagnostic techniques and providing a foundation for future research and development in this critical area.
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  • 文章类型: Journal Article
    随着慢性非特异性脊柱疼痛的患病率上升,用于治疗干预的各种按摩设备的使用迅速增加。然而,研究它们的机制,尤其是那些涉及脊柱扭曲的,是有限的。这项研究旨在评估热应用和脊柱扭转按摩技术对患有慢性非特异性脊柱疼痛的个体的影响。总共36个人被分为两组:对照组(18名参与者)和实验组(18名参与者)。实验组接受热疗加脊椎扭曲按摩,每周两次,共四周,对照组给予热疗加传统振动按摩技术。使用视觉模拟量表(VAS)测量有效性,压力疼痛阈值(PPT),韩国西安大略省和麦克马斯特大学(K-WOMAC)指数,脊柱倾斜,和Cobb角。VAS,K-WOMAC,在所有三个时间点,两组的PPT均显着改善。与对照组相比,实验组中的VAS显著降低(p值:0.0369)。尽管实验组内的K-WOMAC和PPT得分有所改善,统计意义仍然难以捉摸。此外,从基线到第6周,脊柱倾斜和Cobb角没有显着差异。总之,热疗结合扭曲按摩的应用证明了缓解慢性非特异性脊柱疼痛的显着疗效,超越了通过热疗法结合标准振动按摩技术获得的疼痛缓解效果。
    As the prevalence of chronic non-specific spinal pain rises, the utilization of diverse massage devices for therapeutic intervention increases rapidly. However, research on their mechanisms, particularly those involving spinal twisting, is limited. This study was designed to evaluate the impact of heat application and spinal twisting massage techniques on individuals suffering from chronic non-specific spinal pain. A total of 36 individuals were divided into two groups: a control group (18 participants) and an experimental group (18 participants). The experimental group received heat treatment plus spinal twisting massage twice a week for four weeks, while the control group received heat therapy plus traditional vibration massage techniques. Effectiveness was measured using the Visual Analog Scale (VAS), the Pressure Pain Threshold (PPT), the Korean Western Ontario and McMaster Universities (K-WOMAC) Index, spine tilt, and Cobb angle. VAS, K-WOMAC, and PPT significantly improved in both groups at all three time points. VAS notably decreased in the experimental group compared to the control group (p-value: 0.0369). Despite improvements in K-WOMAC and PPT scores within the experimental group, statistical significance remained elusive. Furthermore, spine tilt and Cobb angle showed no significant differences from baseline to the 6th week. In conclusion, the application of thermotherapy coupled with twisting massage demonstrates significant efficacy in mitigating chronic non-specific spinal pain, surpassing the pain-relief outcomes achieved through heat therapy in combination with standard vibration massage techniques.
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  • 文章类型: Journal Article
    背景:病态肥胖是一种复杂的慢性病,其特征在于体重指数为40kg/m2或更高。这种疾病的发病率在发达国家呈上升趋势,减肥手术已被提议作为解决这一趋势的潜在解决方案。尽管如此,减肥手术也可能导致不良影响,包括骨矿物质密度(BMD)和肌肉质量的减少,以及骨折的风险增加。本研究旨在阐明减肥手术和全身振动(WBV)训练对身体成分的影响,微生物群,身体健康,生活质量,和心脏代谢标志物。
    方法:28名参与者(14名女性),18至50岁,将接受袖状胃切除术。他们将被随机分配到对照组或WBV训练组。WBV组将在4个月的训练期内每周训练三次,强度和持续时间从30到45分钟不等。身体成分的测量(双能X射线吸收法和外周定量计算机断层扫描),身体健康(肌肉力量,敏捷性,心肺健康,andbalance),步态生物力学,心脏代谢标志物,肠道菌群,生活质量,和身体活动水平将在四个不同的时间点收集:(1)手术前,(2)术后45天,(3)术后6个月,(4)术后18个月。
    结论:两组在上述大多数变量方面都有望得到改善。尽管如此,我们希望WBV小组表现出更大的改进,证明培训是有效和安全的。
    背景:Clinicaltrials.govNCT05695599。2023年1月25日注册。
    BACKGROUND: Morbid obesity is a complex chronic condition characterized by a body mass index of 40 kg/m2 or higher. The incidence of the condition is on the rise in developed countries, and bariatric surgery has been proposed as a potential solution to address this trend. Nonetheless, bariatric surgery may also result in adverse effects, including a reduction in bone mineral density (BMD) and muscle mass, as well as an increased risk of fractures. The present study aims to elucidate the effects of bariatric surgery and whole-body vibration (WBV) training on body composition, microbiota, physical fitness, quality of life, and cardiometabolic markers.
    METHODS: Twenty-eight participants (14 females), aged 18 to 50 years, will undergo sleeve gastrectomy surgery. They will be randomly allocated into a control group or a WBV training group. The WBV group will train three times per week with increasing intensities and duration ranging from 30 to 45 min over the 4-month training period. Measurements of body composition (dual-energy X-ray absorptiometry and peripheral quantitative computed tomography), physical fitness (muscular strength, agility, cardiorespiratory fitness, and balance), gait biomechanics, cardiometabolic markers, gut microbiota, quality of life, and physical activity levels will be collected at four different time points: (1) prior to the surgery, (2) 45 days post-surgery, (3) 6 months post-surgery, and (4) 18 months post-surgery.
    CONCLUSIONS: Both groups are expected to experience improvements in most of the aforementioned variables. Nonetheless, we expect the WBV group to show larger improvements proving that the training is effective and safe.
    BACKGROUND: Clinicaltrials.gov NCT05695599. Registered on January 25, 2023.
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  • 文章类型: Journal Article
    骨质疏松破坏了骨形成和骨吸收之间的微调平衡,导致骨数量和质量减少,最终增加骨折风险。预防和治疗骨质疏松性骨折对于降低死亡率至关重要。发病率,和经济负担,特别是考虑到全球人口老龄化。完全脊髓损伤(SCI)后,瘫痪肢体中出现了模仿时间加速的骨质疏松症的极端骨质流失。体外纳米级振动(1kHz,30或90nm振幅)已显示可驱动间充质干细胞向成骨细胞样表型分化,同时增强骨生成和抑制破骨细胞生成。这里,我们开发并表征了一种可穿戴设备,旨在向完全SCI大鼠的后肢长骨传递和监测连续的纳米振幅振动。我们调查临床上是否可行的纳米振动剂量(每天2小时,5天/周,持续6周)可有效逆转已建立的SCI诱导的骨质疏松症。激光干涉和有限元分析证实了纳米振动进入骨骼的传输,和显微计算机断层扫描和血清骨形成和吸收标志物评估有效性。干预没有逆转SCI诱导的骨质疏松症。然而,血清分析表明,在接受40nm振幅纳米振动的大鼠中,骨形成标志物1型前胶原N端前肽(P1NP)的浓度升高,提示1型胶原蛋白的合成增加,骨骼的主要有机成分。因此,增强剂量的纳米振动刺激可能对减轻/逆转骨质疏松症有益,特别是在不太严重的骨质疏松症中。
    Osteoporosis disrupts the fine-tuned balance between bone formation and resorption, leading to reductions in bone quantity and quality and ultimately increasing fracture risk. Prevention and treatment of osteoporotic fractures is essential for reductions in mortality, morbidity, and the economic burden, particularly considering the aging global population. Extreme bone loss that mimics time-accelerated osteoporosis develops in the paralyzed limbs following complete spinal cord injury (SCI). In vitro nanoscale vibration (1 kHz, 30 or 90 nm amplitude) has been shown to drive differentiation of mesenchymal stem cells toward osteoblast-like phenotypes, enhancing osteogenesis and inhibiting osteoclastogenesis simultaneously. Here, we develop and characterize a wearable device designed to deliver and monitor continuous nanoamplitude vibration to the hindlimb long bones of rats with complete SCI. We investigate whether a clinically feasible dose of nanovibration (two 2 h/day, 5 days/week for 6 weeks) is effective at reversing the established SCI-induced osteoporosis. Laser interferometry and finite element analysis confirmed transmission of nanovibration into the bone, and microcomputed tomography and serum bone formation and resorption markers assessed effectiveness. The intervention did not reverse SCI-induced osteoporosis. However, serum analysis indicated an elevated concentration of the bone formation marker procollagen type 1 N-terminal propeptide (P1NP) in rats receiving 40 nm amplitude nanovibration, suggesting increased synthesis of type 1 collagen, the major organic component of bone. Therefore, enhanced doses of nanovibrational stimulus may yet prove beneficial in attenuating/reversing osteoporosis, particularly in less severe forms of osteoporosis.
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