%0 Comparative Study
%T Quantification of Vocal Fold Vibration in Various Laryngeal Disorders Using High-Speed Digital Imaging.
%A Yamauchi A
%A Yokonishi H
%A Imagawa H
%A Sakakibara K
%A Nito T
%A Tayama N
%A Yamasoba T
%J J Voice
%V 30
%N 2
%D Mar 2016
%M 26003886
%F 2.3
%R 10.1016/j.jvoice.2015.04.016
%X <B>OBJECTIVE: </B>To quantify vibratory characteristics of various laryngeal disorders seen by high-speed digital imaging (HSDI).<BR><B>METHODS: </B>HSDI was performed on 78 patients with various laryngeal disorders (20 with polyp, 16 with carcinoma, 13 with leukoplakia, 6 with vocal fold nodule, and 33 with others) and 29 vocally healthy subjects. Obtained data were quantitatively evaluated by frame-by-frame analysis, laryngotopography, digital kymography, and glottal area waveform.<BR><B>RESULTS: </B>Overall, patients with laryngeal pathologies showed greater asymmetry in amplitude, mucosal wave and phase, smaller mucosal wave, and poorer glottal closure than vocally healthy subjects. Furthermore, disease-specific vibratory disturbances that generally agreed with the findings in the literature were quantified: comparing polyp with nodule, differences were noted in longitudinal phase difference, amplitude, and mucosal wave. In comparison with leukoplakia and cancer, nonvibrating area was more frequently noted in cancer.<BR><B>CONCLUSIONS: </B>The HSDI analysis of various voice disorders using multiple methods can help phonosurgeons to properly diagnose various laryngeal pathologies and to estimate the degree of their vocal disturbances.