牛副流感-3病毒(BPI3V)是牛的重要呼吸道病原,导致牛呼吸道疾病综合征(BRDC)。尽管意义重大,对其普遍性的理解仍然支离破碎,特别是在BRDC的更大框架内。本系统综述和荟萃分析旨在使用各种检测方法确定牛体内BPI3V的全球患病率,并强调相关的危险因素。在最初检索的2187篇文章中,选择71人进行分析,覆盖32个国家。根据所采用的检测方法,荟萃分析显示BPI3V患病率存在显著差异.在一般牛群中,使用抗体检测方法观察到的患病率最高,比例为0.64。相比之下,在有BRDC的牛身上,观察到的患病率为0.75.对于抗原检测方法,观察到的患病率为0.15,仅限于有BRDC的牛。在核酸检测中,在普通和BRDC牛群中观察到0.05或0.10的患病率,分别。在病毒分离方法中,在普通和BRDC牛群中观察到0.05或0.04的患病率,分别。这些发现突出了不同方法在鉴定BPI3V方面的检测能力的差异。其他因素,如国家,学习年,合并感染,农场大小,呼吸体征的存在,性别,和体重,也可能影响患病率。大多数研究都是基于更广泛的BRDC调查或旨在检测其他疾病,表明重点BPI3V研究的潜在代表性不足。BPI3V在BRDC中起着重要作用,根据检测方法,其患病率差异很大。为了进一步了解其在BRDC中的独特作用,并为有针对性的干预措施铺平道路,显然需要独立,专门研究BPI3V。
Bovine parainfluenza-3 virus (BPI3V) is an important respiratory pathogen in cattle, contributing to syndromes in the bovine respiratory disease complex (BRDC). Despite its significance, the understanding of its prevalence remains fragmented, especially within the larger framework of BRDC. This systematic review and meta-analysis aimed to determine the global prevalence of BPI3V in cattle using varied detection methods and to highlight associated risk factors. Of 2187 initially retrieved articles, 71 were selected for analysis, covering 32 countries. Depending on the detection method employed, the meta-analysis revealed significant variations in BPI3V prevalence. In the general cattle population, the highest prevalence was observed using the antibody detection method, with a proportion of 0.64. In contrast, in cattle with BRDC, a prevalence of 0.75 was observed. For the antigen detection method, a prevalence of 0.15 was observed, exclusively in cattle with BRDC. In nucleic acid detection, a prevalence of 0.05 or 0.10 was observed in the general and BRDC cattle populations, respectively. In virus isolation methods, a prevalence of 0.05 or 0.04 was observed in the general and BRDC cattle populations, respectively. These findings highlight the differences in the detection ability of different methods in identifying BPI3V. Other factors, such as country, study year, coinfections, farm size, the presence of respiratory signs, sex, and body weight, may also affect the prevalence. Most studies were anchored within broader BRDC investigations or aimed at detecting other diseases, indicating a potential under-representation of focused BPI3V research. BPI3V plays an important role in BRDC, with its prevalence varying significantly based on the detection methodology. To further understand its unique role within BRDC and pave the way for targeted interventions, there is an evident need for independent, dedicated research on BPI3V.