■在一般糖尿病中已发现轻度-中度认知障碍,早期证据表明,糖尿病相关足部并发症(DRFC)患者的认知功能下降可能更为明显.认知困难可能会阻碍治疗参与和自我管理。这需要进一步解释以优化患者护理和结果。当前的研究旨在使用综合认知措施来表征DRFC患者的认知功能。
■这项横断面队列研究招募了80名来自维多利亚皇家墨尔本医院糖尿病足病房的成年参与者(年龄=63.38,SD=11.40,范围=30-89)。澳大利亚,所有与DRFC。每完成一个全面的认知电池(记忆,注意,执行功能)和分数是使用年龄匹配的人口规范计算的,可用的地方。
■在大多数任务中,DRFC参与者的表现明显差于年龄匹配的标准,在抑制控制中看到最大的递减,口头记忆,口头抽象推理和工作记忆。在视觉学习中也看到了小到中等的减少,口语流利,处理速度和病前功能。人口统计学(教育水平较低,男性)和临床因素(较高的HbA1c,大血管和微血管疾病,糖尿病病程较长)与认知功能较差相关。
■在DRFC患者中发现认知功能明显下降,主要在语言记忆和执行功能领域。教育水平较低,男性和糖尿病严重程度的指标,比如血管疾病,与认知功能较差的风险增加有关。由于DRFC是一个严重的并发症,如果没有成功管理,会带来毁灭性的后果,必须解决自我管理的认知障碍,以优化治疗。
■在线版本包含补充材料,可在10.1007/s40200-023-01381-4获得。
UNASSIGNED: Mild-moderate cognitive impairment has been identified in general diabetes, and early evidence indicates cognitive reductions may be more pronounced in those with diabetes-related foot complications (DRFC). Cognitive difficulties may impede treatment engagement and self-management. This requires further explication to optimise patient care and outcomes. The current study aimed to characterise cognitive function in people with DRFC using comprehensive cognitive measures.
UNASSIGNED: This cross-sectional cohort study recruited 80 adult participants (M age = 63.38, SD = 11.40, range = 30 - 89) from the Royal Melbourne Hospital Diabetic Foot Unit in Victoria, Australia, all with DRFC. Each completed a comprehensive cognitive battery (memory, attention, executive functions) and scores were calculated using age-matched population norms, where available.
UNASSIGNED: On the majority of tasks, DRFC participants performed significantly worse than age-matched norms, with the largest decrements seen in inhibition control, verbal memory, verbal abstract reasoning and working memory. Small to moderate reductions were also seen in visual learning, verbal fluency, processing speed and premorbid functioning. Demographic (lower education, male gender) and clinical factors (higher HbA1c, macrovascular and microvascular disease, longer diabetes duration) were associated with poorer cognitive functioning.
UNASSIGNED: Marked reductions in cognitive functioning were found in individuals with DRFC, predominantly in the domains of verbal memory and executive functioning. Lower education, male gender and indicators of diabetes severity, such as vascular disease, are associated with heightened risk for poorer cognitive functioning. As DRFCs are a serious complication with devastating outcomes if not successfully managed, cognitive barriers to self-management must be addressed to optimise treatment.
UNASSIGNED: The online version contains supplementary material available at 10.1007/s40200-023-01381-4.