■睡眠障碍是一种高度流行的疾病,尽管先前的研究表明吸烟与睡眠障碍之间存在联系,缺乏大规模,具有全国代表性的研究在多个睡眠结局中检查这种关联,并探索剂量-反应关系.
■这项研究使用了来自NHANES数据库(2007-2020)的30,269名参与者的数据。加权逻辑回归模型用于评估吸烟状况(非吸烟者,轻度吸烟者,适度吸烟,和重度吸烟者)和各种睡眠结果,包括睡眠时间不足,报告睡眠问题,打鼾,哼,或者在睡眠期间停止呼吸,和白天嗜睡。使用受限三次样条探索剂量-反应关系。
■与非吸烟者相比,重度吸烟者睡眠时间不足的几率明显较高,OR为1.732(95%CI1.528-1.963,P<0.001),报告的睡眠问题OR为1.990(95%CI1.766-2.243,P<0.001),偶尔或频繁打鼾,OR为1.908(95%CI1.164-3.128,P=0.03),睡眠期间偶尔或频繁打鼾或停止呼吸,OR为1.863(95%CI1.183-2.936,P=0.022),虽然结果有时,白天经常或几乎总是过度困倦,OR为1.257(95%CI0.872-1.810,P=0.115)并不显著。吸烟与所有睡眠障碍结局呈正相关(P<0.05)。剂量反应分析显示,这些睡眠结果的几率随着吸烟水平的升高而增加。
■吸烟与各种睡眠障碍显著相关,吸烟水平和经历这些睡眠问题的几率之间存在剂量反应关系。这些发现强调了将吸烟作为睡眠健康不良的可改变风险因素的重要性,并建议减少吸烟,即使没有完全停止,可能会对睡眠结果产生积极影响。
UNASSIGNED: Sleeping disorders is a high prevalent disorder, and although previous research has suggested a link between smoking and sleep disorders, there is a lack of large-scale, nationally representative studies examining this association across multiple sleep outcomes and exploring dose-response relationships.
UNASSIGNED: This study used data from 30,269 participants from the NHANES database (2007-2020). Weighted logistic regression models were used to assess the associations between smoking status (non-smoker, light smoker, moderate smoker, and heavy smoker) and various sleep outcomes, including insufficient sleep duration, reported sleep problems,
snoring, snorting, or stopping breathing during sleep, and daytime sleepiness. Dose-response relationships were explored using restricted cubic splines.
UNASSIGNED: Compared to non-smokers, heavy smokers had significantly higher odds of experiencing insufficient sleep duration with OR 1.732 (95% CI 1.528-1.963, P <0.001), reported sleep problems with OR 1.990 (95% CI 1.766-2.243, P <0.001), occasional or frequent
snoring with OR 1.908 (95% CI 1.164-3.128, P = 0.03), and occasional or frequent snorting or stopping breathing during sleep with OR 1.863 (95% CI 1.183-2.936, P = 0.022), while results for sometimes, often or almost always being overly sleepy during the day with OR 1.257 (95% CI 0.872-1.810, P = 0.115) are not significant. A trend of positive correlation was observed between smoking and all sleep disorder outcomes (P for trend < 0.05). Dose-response analyses revealed that the odds of these sleep outcomes increased with higher smoking levels.
UNASSIGNED: Smoking is significantly associated with various sleep disorders, and a dose-response relationship exists between smoking levels and the odds of experiencing these sleep problems. These findings underscore the importance of addressing smoking as a modifiable risk factor for poor sleep health and suggest that reducing smoking, even if complete cessation is not achieved, may have positive effects on sleep outcomes.