Abstract：
Sleep-related breathing disorders, encompassing snoring and obstructive sleep apnea (OSA), are highly prevalent worldwide, and there have been important advances in recent years regarding the understanding of underlying pathophysiology mechanisms, diagnosis, and improvement in therapeutic options. The precision medicine and person-centered approaches are based on the concept that every individual is unique and a myriad of elements influence the likelihood of developing the disease, the signs and symptoms expressed, the response to different treatment modalities, and the susceptibility to complications. Thus, health and disease are the result of phenotypic outcomes resulting from interactions between biological factors, environment, and lifestyle.
摘要：
睡眠相关的呼吸障碍,包括打鼾和阻塞性睡眠呼吸暂停（OSA），在世界范围内非常普遍，近年来，在理解潜在的病理生理机制方面取得了重要进展，诊断,以及治疗选择的改进。精准医学和以人为中心的方法基于这样一个概念，即每个人都是独一无二的，无数的因素影响着疾病的发展可能性。所表达的体征和症状，对不同治疗方式的反应，以及对并发症的易感性。因此，健康和疾病是生物因素之间相互作用导致的表型结果的结果，环境,和生活方式。
