Abstract：
OBJECTIVE: The aim of the study was to examine the prevalence of sleep-disordered breathing (SDB) in children and adolescents with large overjet due to mandibular retrognathia compared to a control group.
METHODS: In this case-control study children with large overjet ≥ 6 mm due to mandibular retrognathia (study group) were compared to a group with neutral occlusion (controls). All participants underwent respiratory polygraphy (PG) and questionnaires regarding sleepiness and snoring. Differences across groups were tested by: Chi-square, general linear model adjusted for age, sex, and body mass index (BMI), and Mann-Whitney test. Differences in results of PG were also tested by general linear model adjusted for age, sex, and BMI according to severity of mandibular retrognathia.
RESULTS: Thirty-seven (19 male;18 female, median age 12.3 years) participants were included in the study group and 32 (16 male;16 female, median age 12.2 years) in the control group. No significant difference in SDB assessed by PG or questionnaires between the groups was found even though the snore index was higher in the study group (p=0.051). The snore index was higher than the parent-reported snoring. Respiration rate was significantly reduced in the study group (p=0.043), and estimated sleep time efficiency was significantly reduced in males compared to females (p<0.001).
CONCLUSIONS: No significant differences in SDB were found between the groups even though the snore index was higher in the study group. The snore index of the PG was higher than the parent-reported snoring. Estimated sleep time efficiency was reduced in males. The study improves the understanding of risk of SDB in non-obese children with large overjet due to mandibular retrognathia and may contribute to an interdisciplinary approach of risk assessment of SDB in children with malocclusion.
BACKGROUND: NCT04964830.
METHODS: In this case-control study children with large overjet ≥ 6 mm due to mandibular retrognathia (study group) were compared to a group with neutral occlusion (controls). All participants underwent respiratory polygraphy (PG) and questionnaires regarding sleepiness and snoring. Differences across groups were tested by: Chi-square, general linear model adjusted for age, sex, and body mass index (BMI), and Mann-Whitney test. Differences in results of PG were also tested by general linear model adjusted for age, sex, and BMI according to severity of mandibular retrognathia.
RESULTS: Thirty-seven (19 male;18 female, median age 12.3 years) participants were included in the study group and 32 (16 male;16 female, median age 12.2 years) in the control group. No significant difference in SDB assessed by PG or questionnaires between the groups was found even though the snore index was higher in the study group (p=0.051). The snore index was higher than the parent-reported snoring. Respiration rate was significantly reduced in the study group (p=0.043), and estimated sleep time efficiency was significantly reduced in males compared to females (p<0.001).
CONCLUSIONS: No significant differences in SDB were found between the groups even though the snore index was higher in the study group. The snore index of the PG was higher than the parent-reported snoring. Estimated sleep time efficiency was reduced in males. The study improves the understanding of risk of SDB in non-obese children with large overjet due to mandibular retrognathia and may contribute to an interdisciplinary approach of risk assessment of SDB in children with malocclusion.
BACKGROUND: NCT04964830.
摘要：
目的：这项研究的目的是研究儿童和青少年由于下颌下颌后移引起的过度喷射的睡眠呼吸障碍（SDB）的患病率，与对照组相比。
方法：在本病例对照研究中，由于下颌下颌后移而导致大的过度喷射≥6mm的儿童（研究组）与中性咬合组（对照组）进行了比较。所有参与者都接受了呼吸测谎仪（PG）和有关嗜睡和打鼾的问卷调查。组间差异通过卡方检验，根据年龄调整的一般线性模型，性别,和体重指数（BMI），和Mann-Whitney测试.PG结果的差异也通过调整年龄的一般线性模型进行了测试，性别,和BMI根据下颌后移的严重程度。
结果：37（男性19；女性18，中位年龄12.3岁)的参与者被纳入研究组，32人(16名男性；16名女性，对照组的中位年龄12.2岁）。即使研究组的打鼾指数较高（p=0.051），通过PG或问卷调查评估的SDB在两组之间也没有显着差异。打鼾指数高于父母报告的打鼾指数。研究组的呼吸率显著降低（p=0.043），与女性相比，男性的估计睡眠时间效率显着降低（p<0.001）。
结论：尽管研究组的打鼾指数较高，但两组之间的SDB没有显着差异。PG的打鼾指数高于父母报告的打鼾。男性的估计睡眠时间效率降低。该研究提高了对非肥胖儿童由于下颌骨回颌引起的大过度喷射的SDB风险的理解，并可能有助于对患有错牙合的儿童进行SDB风险评估的跨学科方法。
背景：NCT04964830。
方法：在本病例对照研究中，由于下颌下颌后移而导致大的过度喷射≥6mm的儿童（研究组）与中性咬合组（对照组）进行了比较。所有参与者都接受了呼吸测谎仪（PG）和有关嗜睡和打鼾的问卷调查。组间差异通过卡方检验，根据年龄调整的一般线性模型，性别,和体重指数（BMI），和Mann-Whitney测试.PG结果的差异也通过调整年龄的一般线性模型进行了测试，性别,和BMI根据下颌后移的严重程度。
结果：37（男性19；女性18，中位年龄12.3岁)的参与者被纳入研究组，32人(16名男性；16名女性，对照组的中位年龄12.2岁）。即使研究组的打鼾指数较高（p=0.051），通过PG或问卷调查评估的SDB在两组之间也没有显着差异。打鼾指数高于父母报告的打鼾指数。研究组的呼吸率显著降低（p=0.043），与女性相比，男性的估计睡眠时间效率显着降低（p<0.001）。
结论：尽管研究组的打鼾指数较高，但两组之间的SDB没有显着差异。PG的打鼾指数高于父母报告的打鼾。男性的估计睡眠时间效率降低。该研究提高了对非肥胖儿童由于下颌骨回颌引起的大过度喷射的SDB风险的理解，并可能有助于对患有错牙合的儿童进行SDB风险评估的跨学科方法。
背景：NCT04964830。
