respiratory problems

呼吸系统问题
  • DOI:
    文章类型: English Abstract
    BACKGROUND: waste electrical and electronic equipment (WEEE), with its health and environmental issues, has become a public health problem exposing workers to toxic compounds causing respiratory problems.
    OBJECTIVE: To study the relationship between professional exposure to WEEE and the occurrence of respiratory problems in Bamako in 2019.
    METHODS: This was a 6-month cross-sectional, analytical study carried out in the city of Bamako in 2019 and involved 159 WEEE manipulators. Data were collected using a tablet (2). Univariate and multivariate analyzes were performed using SPSS version 22 with the significance level of 0.05. Odds Ratio (OR) were presented with their 95% confident interval (OR[95%CI]).
    RESULTS: The overall prevalence of respiratory disorders was 67.3% among WEEE handlers. It was noted that the removal of the coating of electronic wires (OR[95%CI]=25.93[2.30;291.53]), recent weight loss outside of a diet (OR[95% CI]=7,43[1.68;32.85]) and the infrequent hand washing with soap after the toilet (OR[95% CI]=11.50[2.07; 63.89]) represented a higher risk of (2) breathing problems.
    CONCLUSIONS: These results show that D3E handlers have a lot of risky behavior for respiratory problems. This study could be used to implement strategies to reduce the impact of D3E.
    BACKGROUND: les déchets d\'équipements électriques et électroniques (D3E), avec leurs enjeux sanitaires et environnementaux, sont devenus un problème de santé publique exposant les travailleurs aux composés d\'éléments toxiques responsables de (2ème expertise) troubles respiratoires.
    OBJECTIVE: Etudier la relation entre l\'exposition professionnelle aux D3E et la survenue des problèmes respiratoires à Bamako en 2019.
    UNASSIGNED: Il s\'agissait d\'une étude transversale, analytique de 6 mois, menée dans la ville de Bamako en 2019 et concernait 159 manipulateurs de D3E. Les données ont été collectées sur tablette et les analyses univariées et multivariées réalisées sur SPSS version 22 au seuil de significativité de 0,05 avec présentation des Odds Ratio (OR) et leurs intervalles de confiance à 95% (OR[IC95%]).
    UNASSIGNED: La prévalence en général des troubles respiratoires était de 67,3% chez les manipulateurs des D3E. On notait que le retrait du revêtement des fils électroniques (OR[IC95%]=25,93[2,30;291,53]), la perte de poids récente en dehors d\'un régime (OR[IC95%]=7,43[1,68;32,85]) et la rareté de lavage des mains avec du savon après les toilettes (OR[IC95%]=11,50[2,07;63,89]) représentaient un risque plus élevé de problèmes respiratoires.
    CONCLUSIONS: Ces résultats montrent que les manipulateurs de D3E ont beaucoup de comportement à risque des problèmes respiratoires. Cette étude pourrait servir à la mise en œuvre de stratégies visant à réduire l\'impact des D3E.
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  • 文章类型: Systematic Review
    目的:本研究的目的是对纺织和时装业工厂工人的健康相关问题进行系统综述。这些工人暴露于长时间的坐姿,恶劣的工作空间条件和长时间工作以完成过载任务。这种情况会导致一些影响生产力的健康问题,工人的精神和福祉。
    方法:相关数据(21篇文章出版物)来自Scopus数据库。根据对内容和摘要的批判性阅读,对21(21)篇文章的分析分为三个研究主题:呼吸问题,肌肉骨骼疾病(MSD),and,心理压力和其他健康问题。
    结果:研究结果表明,工厂工人暴露于棉花和其他原材料的灰尘颗粒中,烟雾,和制造过程中的化学品。在不使用个人防护设备的情况下长时间暴露,导致呼吸道疾病,如byssinosis,影响工人的健康。此外,工作在一个特定的姿势,由于长时间的工作站设计导致肌肉骨骼疾病或疼痛。工人也患有焦虑,抑郁症和,工作负载和压力带来的压力,从而使它们不稳定,生产率降低。
    结论:研究结果强调了对良好安全工作空间和宽敞工作环境的需求,提供个人防护设备,职业危害培训,频繁的健康检查,并对工作站进行人体工程学评估,以减少长时间的工作姿势。利益相关者,雇主,政策制定者,政府应合作,以保障和保护工厂工人的福祉和健康。
    UNASSIGNED: The purpose of this study was to present a systematic review of the health-related problems of factory workers in the textile and fashion industry. These workers endure long sitting postures, poor workspace conditions, and long working hours to complete their overload of tasks. This situation results in several health problems that affect the productivity, mental health, and well-being of the workers.
    UNASSIGNED: The relevant data (21 article publications) were obtained from the Scopus database. Analysis of the 21 articles was grouped under 3 research themes based on the critical reading of the content and abstracts: respiratory problems, musculoskeletal disorders, and psychological stressors and other health issues.
    UNASSIGNED: The findings show that factory workers are exposed to dust particles of cotton and other raw materials, fumes, and chemicals from manufacturing processes. This prolonged exposure without the use of personal protective equipment (PPE) leads to respiratory diseases like byssinosis that affect the workers\' health. Additionally, working in a particular posture due to the workstation design for prolonged hours causes musculoskeletal disorders or pains. Workers also suffer from anxiety, depression, and stress from workload and pressure, hence making them unstable with reduced productivity.
    UNASSIGNED: The findings of the study reinforce the need for a safe workspace and spacious work environment, provision of PPE, training in occupational hazards, frequent health checks, and ergonomic assessment of workstations to reduce prolonged work postures. Stakeholders, employers, policymakers, and governments should collaborate to safeguard and protect the well-being and health of the workers at these factories.
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  • 文章类型: Journal Article
    原发性纤毛运动障碍(PCD)是一种罕见的,由活动纤毛功能障碍引起的具有可变特征的慢性遗传状况,包括反复呼吸道感染,鼻窦疾病,听力降低,不育和坐位倒置。该研究的目的是了解PCD年轻人过渡到成年和成人医疗保健服务的经历。采用了解释现象学分析方法。对三名18-24岁的参与者进行了半结构化访谈。确定了四个相互关联的小组体验主题:(1)重新概念化污名化的身份,(2)分享独立之旅,(3)以新发现的自主性进入成年,(4)预测不确定的未来。总的来说,我们发现,对于患有PCD的年轻人来说,过渡是一个以身份形成为标志的复杂时期,建立支持系统,成为一个自主的成年人。应优先考虑促进个性化和综合护理方法。我们的发现对于帮助卫生专业人员提供适当的,预期支持。
    Primary ciliary dyskinesia (PCD) is a rare, chronic genetic condition with variable features arising from motile cilia dysfunction, including recurrent respiratory infections, sinonasal disease, reduced hearing, infertility and situs inversus. The aim of the study was to understand the experiences of young people with PCD as they transition into adulthood and adult healthcare services. An interpretative phenomenological analytical method was applied. Semi-structured interviews were conducted with three participants aged 18-24 years. Four interconnected group experiential themes were identified: (1) reconceptualising a stigmatised identity, (2) sharing the journey to independence, (3) entering adulthood with newfound autonomy, (4) anticipating an uncertain future. Overall, we found that transition for young people with PCD presents as a complex period marked by identity-formation, creating systems of support and becoming an autonomous adult. Facilitation of personalised and integrated approaches to care should be prioritised. Our findings are important to help health professionals provide appropriate, anticipatory support.
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  • 文章类型: Journal Article
    这项研究的目的是研究个人因素之间的关系,在家里暴露烟雾,以及纳空斯坦马拉特省儿童早期的呼吸系统问题,泰国。
    本研究为回顾性研究。研究中总共有414个样本。这些工具包括关于幼儿及其照顾者的个人数据的问卷,烟雾暴露评估表,和儿童早期呼吸系统问题评估表。个人因素之间的关系,在家里暴露烟雾,通过卡方检验和二元逻辑回归分析了儿童早期的呼吸问题。
    结果显示,儿童早期在家中的烟雾暴露是适度的(52.2%)。68.8%有呼吸问题。出生体重之间的关系,发现幼儿家庭吸烟与呼吸系统问题显着相关(X2=5.014p<0.05和X2=85.711p<0.001)。发现出生体重≤2500g的儿童在出生体重>2500g的样本的2.55倍时出现呼吸问题(AOR=2.55,95%CI:1.10-5.96),中高烟雾暴露样本的呼吸问题是低烟雾暴露样本的8.86倍(AOR=8.86,95%CI:5.39-14.60)。营养状况和母乳喂养与幼儿呼吸问题无显著相关,p>0.05。
    发现出生体重和家庭吸烟因素与儿童早期的呼吸问题有关。因此,有必要减少刺激,尤其是在家里吸烟。此外,儿童早期的标准出生体重会降低呼吸系统问题的发生率。
    UNASSIGNED: The purpose of this study was to examine the relationship between personal factors, smoke exposure at home, and respiratory problems in early childhood in Nakhon Si Thammarat Province, Thailand.
    UNASSIGNED: This study was retrospective. There was a total of 414 samples in the study. The instruments included the questionnaire about the personal data of early childhood and their caregivers, the smoke exposure assessment form, and the early childhood respiratory problem assessment form. The relationship between personal factors, smoke exposure at home, and respiratory problems in early childhood was analyzed by the Chi-squared test and binary logistic regression.
    UNASSIGNED: The results revealed that smoke exposure at home in early childhood was moderate (52.2%). There 68.8% had respiratory problems. The relationship between birth weight, and smoke exposure at home in early childhood was found to be significantly related to respiratory problems (X2 =5.014 p< 0.05 and X2 = 85.711 p< 0.001, respectively). It was found that children with a birth weight ≤2500g had respiratory problems at 2.55 times of the samples with birth weight >2500g (AOR = 2.55, 95% CI: 1.10-5.96), and moderate-high smoke exposure had respiratory problems at 8.86 times of the samples with low smoke exposure (AOR = 8.86, 95% CI: 5.39-14.60). Nutritional status and breastfeeding were not significantly related to respiratory problems in early childhood p > 0.05.
    UNASSIGNED: The birth weight and smoke exposure at home factors were found to be related to their respiratory problems in early childhood. Thus, it is necessary to reduce stimuli, especially smoking at home. Moreover, the standard birth weight of their early childhood will reduce the rate of respiratory problems.
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  • 文章类型: Journal Article
    团注残留是吞咽后误吸的重要危险因素。进行了一项回顾性研究,以评估食道闭锁患儿食团残留物的作用及其与呼吸问题的关系。评估儿童的人口统计特征,食管闭锁类型,相关异常,和呼吸问题。进行视频透视吞咽评估(VFSE),并使用渗透抽吸量表(PAS)进行评分,团注残差评分(BRS)和归一化残差比量表(NRRS)。还比较了有和没有呼吸问题的儿童的吸入和推注残留物。41名儿童,中位年龄为15个月(1-138个月),男性:女性比例为26:15。65.9%(n=27)的儿童为C型,24.4%(n=10)的儿童为A型EA。61%(n=25)的儿童有液体吸入(PAS≥6),9.8%(n=4)的儿童有布丁稠度吸入。与没有吸入性的儿童相比,吸入性液体的儿童在布丁稠度的瓣膜残留物中的NRRS和BRS评分明显更高(p<0.05)。在有和没有呼吸问题的儿童之间,PAS评分和推注残留参数没有发现差异(p>0.05)。误吸液体的儿童在谷类水平上的BRS和NRRS得分较高,尤其是在布丁稠度方面。推注残留物的VFSE发现与呼吸问题没有显着关系。EA患儿的呼吸道发病率是多因素的,不仅可以通过食团残留和误吸来解释。
    Bolus residue is significant risk factor for postswallow aspiration. A retrospective study was performed to evaluate the role of bolus residue and its relation with respiratory problems in children with esophageal atresia. Children were evaluated for demographic features, type of esophageal atresia, associated anomalies, and respiratory problems. The videofluoroscopic swallowing evaluation (VFSE) was performed, and scored by using the penetration aspiration scale (PAS), bolus residual score (BRS) and normalized residual ratio scale (NRRS). Children with and without respiratory problems were also compared in terms of aspiration and bolus residue. Forty-one children with a median age of 15 months (1-138 months), male:female ratio of 26:15 was included. 65.9% (n = 27) of children were type-C and 24.4% (n = 10) were type-A EA. In 61% (n = 25) of children had liquid aspiration (PAS ≥ 6) and 9.8% (n = 4) had aspiration in pudding consistencies. Children with aspiration in liquids had significantly higher NRRS and BRS scores in vallecular residue for pudding consistencies when compared to children without aspiration (p < 0.05). No difference was detected in terms of PAS scores and bolus residual parameters between children with and without respiratory problems (p > 0.05). Children with aspiration in liquids have higher scores of BRS and NRRS at the level of vallecular especially in pudding consistencies. VFSE findings for bolus residue did not show significant relation with respiratory problems. Respiratory morbidity in children with EA is multifactorial and may not only explained by bolus residuals and aspiration.
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  • 文章类型: Journal Article
    目的:比较不完全疗程和超过1疗程的地塞米松的效果,相对于单个完整课程的控制,胎儿呼吸问题和早产的其他不良后果。
    方法:这是1800名早产妇女的回顾性图表回顾。收集了母亲服用1个疗程地塞米松的新生儿的数据(916/1800;50.9%),部分课程(716/1800;39.8%)和1个以上课程(168/1800;9.3%)。记录人口统计学数据以及不良的母婴结局。
    结果:母亲接受几个类固醇激素疗程的早产单胎新生儿比母亲接受1疗程的新生儿更有可能出现不良结局。阴性结果是需要正压通气([aOR]1.831;95%CI,(1.185,2.829);P=0.019),呼吸机支持([aOR]1.843;95%CI,(1.187,2.861);P=0.011),和光疗([aOR]1.997;95%CI,(1.378,2.895);P<0.001),新生儿短暂性呼吸急促([aOR]1.801;95%CI,(1.261,2.571);P=0.002),脑室内出血([aOR]2.215;95%CI,(1.159,4.233);P=0.027),脓毒症([aOR]1.737;95%CI,(1.086,2.777);P=0.007),和入院新生儿重症监护([aOR]1.822;95%CI,(1.275,2.604);P=0.001)。在非常早产儿组中,与接受单疗程治疗的母亲相比,接受不完全疗程治疗的母亲的新生儿出现呼吸窘迫综合征(RDS)([aOR]3.177;95%CI,(1.485,6.795);P=0.006)和使用通气支持([aOR]3.565;95%CI,(1.912,6.650);P<0.001)。
    结论:母亲接受多疗程地塞米松治疗的早产单胎新生儿与接受全疗程治疗的母亲相比,RDS和其他不良结局的发生率增加。然而,母亲接受1个完整地塞米松疗程的极早产新生儿的RDS发生率明显低于母亲接受部分疗程的新生儿.
    OBJECTIVE: To compare the effects of an incomplete course and more than 1 course of dexamethasone, relative to a control of a single complete course, on foetal respiratory problems and other adverse outcomes of preterm birth.
    METHODS: This was a retrospective chart review of 1800 women with preterm delivery. Data were collected on newborns whose mothers administered 1 full course of dexamethasone (916/1800; 50.9%), a partial course (716/1800; 39.8%) and more than 1 course (168/1800; 9.3%). Demographic data and adverse maternal and neonatal outcomes were recorded.
    RESULTS: Preterm singleton newborns whose mothers received several steroid hormone courses were significantly more likely to have adverse outcomes than newborns of mothers given 1 course. The negative outcomes were the need for positive pressure ventilation ([aOR] 1.831; 95% CI, (1.185,2.829); P = 0.019), ventilator support ([aOR] 1.843; 95% CI, (1.187,2.861); P = 0.011), and phototherapy ([aOR] 1.997; 95% CI, (1.378,2.895); P <  0.001), transient tachypnoea of the newborn ([aOR] 1.801; 95% CI, (1.261,2.571); P = 0.002), intraventricular haemorrhage ([aOR] 2.215; 95% CI, (1.159, 4.233); P = 0.027), sepsis ([aOR] 1.737; 95% CI, (1.086, 2.777); P = 0.007), and admission to neonatal intensive care ([aOR] 1.822; 95% CI, (1.275,2.604); P = 0.001). In the group of very preterm infants, newborns of mothers administered an incomplete course had developed respiratory distress syndrome (RDS) ([aOR] 3.177; 95% CI, (1.485, 6.795); P = 0.006) and used ventilatory support ([aOR] 3.565; 95% CI, (1.912, 6.650); P <  0.001) more than those of mothers receiving a single course.
    CONCLUSIONS: Preterm singleton newborns whose mothers were given multiple courses of dexamethasone had an increased incidence of RDS and other adverse outcomes than those of mothers receiving a full course. However, very preterm newborns whose mothers were administered 1 full dexamethasone course had a significantly lower incidence of RDS than those whose mothers were given partial courses.
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  • 文章类型: Journal Article
    COVID-19患者和幸存者经常出现抑郁症状,这会增加免疫系统反应降低和恢复不良的风险。在COVID-19病程最严重的患者中,抑郁症状的脆弱性可能会升高,也就是说,需要补充氧疗甚至插管的患者。当前的研究涉及因COVID-19住院并需要呼吸支持的患者的独特样本(N=34,10名女性),其中我们调查了抑郁症状以及精神病理学人格特征(PID5)作为预测因子。大多数患者(76.5%)出现一定程度的抑郁症状。虽然我们预计严重程度的抑郁症状最普遍,更多的患者表现出相当中等的水平。同时,负面情感是抑郁症状的最大预测因素。我们建议对情绪敏感和容易受到压力的患者进行医疗护理,并辅以心理支持,以解决抑郁症状并促进康复。
    COVID-19 patients and survivors quite often experience depressive symptoms, which can increase risk for lower immune system response and poorer recovery. Vulnerability to depressive symptoms may be elevated in those patients who have the most severe COVID-19 course of illness, that is, patients who require supplementary oxygen therapy or even intubation. The current study involved a unique sample of patients who were hospitalized due to COVID-19 and who required respiratory support (N = 34, 10 women) in which we investigated depressive symptoms as well as psychopathological personality traits (PID5) as predictors. The majority of patients (76.5%) presented some degree of depressive symptoms. Although we expected severe levels of depressive symptoms to be most prevalent, more patients showed rather moderate levels. At the same time, Negative Affectivity was most predictive of depressive symptoms. We suggest that medical care for patients with greater emotional sensitivity and vulnerability to stress be supplemented with psychological support in order to address depressive symptoms and foster recovery.
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  • 文章类型: Journal Article
    在环境流行病学的各个方面,一是评估环境空气污染与健康结果之间的关系。这项工作的目的是以参数浓度响应函数(C-RF)的形式估计关联。在这项短期健康效应研究中提出了各种形式的C-RF。作为说明性示例,对所有呼吸健康问题的急诊科(ED)访问进行了分析。案例交叉(CC)技术被用作研究设计。在一个普通月份的一周的同一天,每日病例被组织为每日计数。在构建的统计模型中使用条件泊松回归。温度和相对湿度以自然样条的形式包含在统计模型中。地面臭氧浓度被认为是暴露。转换臭氧浓度值并提交给统计模型。通过使用拟合优度准则来确定变换的参数。分析ED访问次数与一系列滞后的臭氧暴露有关。为每个单独的滞后构造C-RF形状。在最后一步,估计的C-RF形状的集合用于创建汇集的C-RF形状。对于9个滞后暴露,结果是积极的,具有统计学意义,从0到8天。以下相对风险(RR)从构建的C-RFs在30ppb浓度的臭氧:RR=1.0531(95%置信区间:1.0231,1.0718),1.0462(1.0253,1.0677),和1.0387,(1.0240,1.0531),实现CC方法,CC方法+转换,和CC方法+灵活转换,分别。汇集的C-RF形状总结了ED对呼吸状况和环境臭氧的访问之间的关联。估计的形状表明比标准CC方法更低的空气健康影响。在三个考虑的统计模型中,根据拟合优度准则,CC方法+柔性变换是最合适的。
    Among various aspects of environmental epidemiology, one is to assess the relationships between ambient air pollution and health outcomes. The goal of this work is to estimate the associations in the form of the parametric concentration-response functions (C-RF). Various forms of the C-RFs are proposed in this short-term health effect study. Emergency department (ED) visits for all respiratory health problems are analyzed as an illustrative example. A case-crossover (CC) technique is applied as a study design. Daily cases are organized as daily counts by the same day of the week in one common month. A conditional Poisson regression is used in the constructed statistical models. Temperature and relative humidity are included in the statistical models in the form of natural splines. Ground-level ozone concentration is considered an exposure. Ozone concentration values are transformed and submitted to the statistical models. The parameters of the transformation are determined by using the goodness of fit criterion. Counts of ED visits are analyzed in relation to a sequence of lagged exposure to ozone. The C-RF shapes are constructed for each individual lag. In a final step, the set of the estimated C-RF shapes is used to create a pooled C-RF shape. The results are positive and statistically significant for nine lagged exposures, from 0 to 8 days. The following relative risks (RR) were estimated from the constructed C-RFs at 30 ppb concentration of ozone: RR = 1.0531 (95% confidence interval: 1.0231, 1.0718), 1.0462 (1.0253, 1.0677), and 1.0387, (1.0240, 1.0531), realizing the CC method, CC method + transformation, and CC method + flexible transformation, respectively. The pooled C-RF shape gives a summary of the associations between ED visits for respiratory conditions and ambient ozone. The estimated shapes indicate lower air health effects than the standard CC methods. Among three considered statistical models, the CC method + flexible transformation is the most appropriate to use according to the goodness of fit criterion.
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  • 文章类型: Journal Article
    空气传播的花粉被认为是导致发病率并随后影响人的生活质量(QOL)的呼吸系统疾病的主要触发因素。户外工作者,比如园丁,花店,等。,由于持续暴露于高浓度的过敏原,过敏的风险更大。本研究旨在评估园丁因职业暴露于空气中的花粉而产生的相关健康风险。在昌迪加尔的园丁(496)中进行了基于半结构化问卷的调查,涵盖他们的社会人口状况,职业和环境史,以及呼吸和其他与健康有关的问题。在该市26个花园的496名受访者中,72.58%属于植物人(马里)类别,其次是15.72%的割草机和3.02%的头马/主管。大多数园丁是男性(95.76%),最大数量的受访者在29-38岁年龄段(27.41%)。其中,4.2%,3.6%,3.2%的受访者认为呼吸急促和呼吸困难。同时,3.2%的受访者认为他们的呼吸永远不会完全令人满意,令人惊讶,他们都是植物人(马里)。此外,18.9%的受访者用布遮住了脸,只有0.5%的受访者同时戴着眼镜并用布遮住了脸。在所有受访者中,6.5%的人报告在没有佩戴任何个人防护装置的情况下眼睛受到刺激。结果表明,很大一部分园丁是文盲,不知道工作场所的职业危害和花粉过敏。此外,监管机构不进行正式的健康意识和培训/教育会议,以尽量减少暴露和相关风险。这项研究的结果将有助于更好地了解职业园丁的工作条件和健康状况,以及开发适当的方法来改善他们的工作条件。
    Airborne pollen are considered a major trigger of respiratory diseases that causes morbidity and subsequently affects a person\'s quality of life (QOL). Outdoor workers, such as gardeners, florists, etc., are at greater risk of allergies due to continuous exposure to the high concentration of allergens. The current study aims to assess the associated health risks among gardeners due to occupational exposure to airborne pollen. A semi-structured questionnaire-based survey was conducted among gardeners (496) in Chandigarh, covering their socio-demographic status, occupational and environmental history, and respiratory and other health-related problems. Out of 496 respondents from 26 gardens in the city, 72.58% fall under the category of plantsman (mali), followed by 15.72% of grass cutters and 3.02% of headmali/supervisor. The majority of gardeners were males (95.76%) and a maximum number of respondents were in the age group of 29-38 years (27.41%). Among all, 4.2%, 3.6%, and 3.2% of respondents perceived the problem of shortness of breath and breathing problems. At the same time, 3.2% of respondents perceived that their breathing is never wholly satisfactory and surprisingly, all of them are plantsman (mali). Moreover, 18.9% of the respondents covered their faces with a cloth and only 0.5% of the respondents wore both spectacles and covered their faces with a cloth. Out of all respondents, 6.5% reported irritation in the eyes without wearing any personal protective device. The results show that a large proportion of gardeners are illiterate and unaware of occupational hazards and pollen allergies in their workplaces. Moreover, the regulatory authorities conduct no formal health awareness and training/education sessions to minimize the exposure and associate risk. The findings of the study will aid in a better understanding of the working conditions and health status of occupational gardeners, as well as the development of appropriate methods to improve their working conditions.
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  • 文章类型: Journal Article
    目的:内镜下球囊扩张术(EBD)为声门下狭窄的治疗提供了一种安全且无创的手术选择。患者选择对于取得良好的结果以及检测哪些患者更容易发生并发症很重要。这项研究的目的是确定原发性EBD手术中术后问题和早期并发症的预测因素。
    方法:回顾性分析2010年1月至2019年12月在巴斯肯特大学医院耳鼻咽喉头颈外科行EBD手术的获得性声门下狭窄患者。收集了包括患者年龄和性别在内的人口统计学数据以及病因,染色体或颅面异常(C/CA)的存在,长时间插管(DPI)的持续时间,和拔管扩张时间框架(EDT)。记录术中和术后随访数据,是否需要插管或气管切开术,去饱和的发展,狭窄的级别和类型。
    结果:男女比例为2:1。患者包括42名男性和22名女性,平均年龄为296.52±551.93天。长时间插管的原因是50例(78.1%)先天性心脏病患者的手术和14例(21.9%)的早产。病变类型为急性肉芽44例(72.1%),慢性肉芽17例(27.9%)。在13例患者中确定了C/CA,狭窄的平均级别为76.33±15.21%,平均DPI为25.25±35.49天,平均EDT计算为78.23±373.82天。26例(40.6%)发生内窥镜球囊扩张后的去饱和,10例(15.6%)需要经气管插管,气管切开术10例(15.6%),4例(6.25%)发生心肺骤停。早产,术前插管持续时间较长,从拔管到扩张的时间更长,年龄较大,和更高的狭窄程度被确定为与术后早期呼吸系统并发症相关的因素。
    结论:儿童获得性声门下狭窄应仔细考虑EBD指征。为了获得更好的结果并最大限度地减少并发症,EBD应毫不拖延地进行。
    OBJECTIVE: Endoscopic balloon dilatation (EBD) offers a safe and non-invasive surgical option for the treatment of subglottic stenosis. Patient selection is important to achieve good results and to detect which patients are more prone to the development of complications. The aim of this study was to determine predictors of postoperative problems and early complications in primary EBD surgeries.
    METHODS: A retrospective analysis was made of patients with acquired subglottic stenosis who were operated on with the EBD technique between January 2010 and December 2019 in the Otolaryngology-Head and Neck Surgery Department of Baskent University Hospital. Demographic data including the age and sex of the patients were collected together with etiology, presence of chromosomal or craniofacial anomaly (C/CA), duration of prolonged intubation (DPI), and extubation dilatation timeframe (EDT). Intra and postoperative follow-up data were recorded of the need for intubation or tracheotomy, development of desaturation, and grade and type of stenosis.
    RESULTS: The male to female ratio was 2:1. The patients comprised 42 males and 22 females with a mean age of 296.52 ± 551.93 days. The cause of prolonged intubation was surgery for congenital heart disease in 50 (78.1%) patients and prematurity in 14 (21.9%). The type of lesion was acute granulation in 44 (72.1%) and chronic granulation in 17 (27.9%) patients. C/CA was determined in 13 patients, the mean grade of stenosis was 76.33 ± 15.21%, mean DPI was 25.25 ± 35.49 days, and mean EDT was calculated as 78.23 ± 373.82 days. Desaturation following endoscopic balloon dilatation developed in 26 (40.6%), orotracheal intubation was required in 10 (15.6%), tracheotomy in 10 (15.6%), and cardiopulmonary arrest occurred in 4 (6.25%). Prematurity, a longer duration of preoperative intubation, longer time from extubation to dilatation, older age, and higher grade of stenosis were determined as factors associated with postoperative early respiratory complications.
    CONCLUSIONS: EBD indication should be carefully considered in children with acquired subglottic stenosis. To achieve better results and minimise complications, EBD should be performed without delay.
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