outpatient clinics

门诊诊所
  • 文章类型: English Abstract
    本文介绍了门诊单位(城市综合诊所)在城市医疗机构体系中的特殊作用,在临床研究领域具有巨大的发展潜力。由于为门诊诊所配备最现代的诊断设备的系统工作,这项活动成为可能,根据国际良好临床实践规则,在组织和开展临床试验方面接受过培训的专家的可用性。一个特殊的价值在于,综合诊所网络拥有一个广泛的数据库,其中包括数百万患者,并提供了执行最高水平的医疗专业知识和研究的机会。
    The article presents the special role of the outpatient unit (urban polyclinics) in the system of urban medical organizations, which has significant development potential in the field of clinical research. This activity became possible due to the systematic work on equipping outpatient clinics with the most modern diagnostic equipment, the availability of specialists trained in the organization and conduct of clinical trials according to the international rules of good clinical practice. A special value lies in the fact that the polyclinic network has an extensive database that includes millions of patients and provides the opportunity to perform the highest level of medical expertise and research.
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  • 文章类型: Journal Article
    患者\'错过预约可能会干扰诊所的功能和其他患者的就诊。解决不显示速率问题的最有效策略之一是使用开放访问调度系统(OA)。进行这项系统评价的目的是调查OA对门诊患者未就诊率的影响。
    使用PubMed根据标题和摘要中的关键字调查了英文相关文章,Scopus,以及WebofScience数据库和GoogleScholar搜索引擎(2023年7月23日)。包括使用OA和报告未出现率的文章。排除标准如下:(1)评论文章,意见,和字母,(2)住院排班系统文章,(3)建模或模拟OA文章。从选定的文章中提取有关研究设计等问题的数据,结果衡量标准,干预措施,结果,和质量得分。
    在总共23,403项研究中,选择了16篇文章。专业领域包括家庭医学(62.5%,10),儿科(25%,four),眼科,足病,老年病学,内科,和初级保健(6.25%,一)。在16篇文章中,10篇论文(62.5%)显示出未显示率显著下降。在四篇文章(25%)中,未出现率没有显著降低.在两篇论文(12.5%)中,没有重大变化。
    根据这项研究结果,似乎在大多数门诊诊所,通过考虑一些条件来使用OA,例如根据患者和提供者的实际需求进行需求评估和系统设计,所有系统利益相关者通过持续培训进行合作,导致未显示率大幅下降。
    UNASSIGNED: Patients\' missed appointments can cause interference in the functions of the clinics and the visit of other patients. One of the most effective strategies to solve the problem of no-show rate is the use of an open access scheduling system (OA). This systematic review was conducted with the aim of investigating the impact of OA on the rate of no-show of patients in outpatient clinics.
    UNASSIGNED: Relevant articles in English were investigated based on the keywords in title and abstract using PubMed, Scopus, and Web of Science databases and Google Scholar search engine (July 23, 2023). The articles using OA and reporting the no-show rate were included. Exclusion criteria were as follows: (1) review articles, opinion, and letters, (2) inpatient scheduling system articles, and (3) modeling or simulating OA articles. Data were extracted from the selected articles about such issues as study design, outcome measures, interventions, results, and quality score.
    UNASSIGNED: From a total of 23,403 studies, 16 articles were selected. The specialized fields included family medicine (62.5%, 10), pediatrics (25%, four), ophthalmology, podiatric, geriatrics, internal medicine, and primary care (6.25%, one). Of 16 articles, 10 papers (62.5%) showed a significant decrease in the no-show rate. In four articles (25%), the no-show rate was not significantly reduced. In two papers (12.5%), there were no significant changes.
    UNASSIGNED: According to this study results, it seems that in most outpatient clinics, the use of OA by considering some conditions such as conducting needs assessment and system design based on the patients\' and providers\' actual needs, and cooperating of all system stakeholders through consistent training caused a significant decrease in the no-show rate.
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  • 文章类型: Journal Article
    目的:本研究探索和了解社区成员在门诊诊所的韧性,考虑各种维度和类型的弹性。
    方法:横断面研究。
    方法:这项研究于2023年9月至12月在沙特门诊进行,包括通过系统随机抽样选择的384名个体。使用了各种工具,如社会凝聚力和信任量表,社区复原力评估工具,社区心理体验评估,环境恢复力评估,经济弹性指数,康纳-戴维森弹性量表,简短的弹性量表,成人弹性量表和医疗保健弹性指数。
    结果:参与者表现出强大的整体弹性水平,总Connor-Davidson弹性量表评分63.0±9.0。此外,他们在总短暂复原力量表中表现出了值得称赞的复原力水平(56.04±8.6),成人弹性量表(82.5±7.2)和医疗保健弹性指数(45.8±5.5)。这些发现为研究人群的心理和情感幸福感提供了重要的见解,强调他们在不同生活领域的适应能力和应对机制。
    结论:这项研究为门诊环境中韧性的多维性质提供了有价值的见解。横截面设计为未来的纵向调查奠定了基础,强调需要采取整体方法来理解和促进复原力。
    结论:这项研究对参与者及其社区具有直接意义。通过揭示值得称赞的复原力水平,强调了门诊人群中普遍存在的适应能力和应对机制。这种洞察力增强了个人的心理和情感幸福感,对整体韧性和公共力量做出积极贡献。此外,这项研究揭示了沙特阿拉伯社区成员的韧性与国际先进护理社区的关系,提供对他们工作的洞察力。
    有目的地选择在过去6个月内接受过门诊服务的患者,以确保不同年龄的患者。本研究的性别和社会经济背景。
    OBJECTIVE: This study explores and understands community members\' resilience in outpatient clinics, considering various dimensions and types of resilience.
    METHODS: A cross-sectional study.
    METHODS: This study was conducted in Saudi outpatient clinics from September to December 2023 and included 384 individuals chosen through systematic random sampling. Various tools were used, such as Social Cohesion and Trust Scale, Community Resilience Assessment Tool, Community Assessment of Psychic Experiences, Environmental Resilience Assessment, Economic Resilience Index, Connor-Davidson Resilience Scale, Brief Resilience Scale, Resilience Scale for Adults and Healthcare Resilience Index.
    RESULTS: Participants displayed a robust overall resilience level, as indicated by Total Connor-Davidson Resilience Scale score of 63.0 ± 9.0. Additionally, they demonstrated commendable levels of resilience in Total Brief Resilience Scale (56.04 ± 8.6), Resilience Scale for Adults (82.5 ± 7.2) and Healthcare Resilience Index (45.8 ± 5.5). These findings offer significant insights into psychological and emotional well-being of the study population, highlighting their adaptive capacities and coping mechanisms across various life domains.
    CONCLUSIONS: This study provides valuable insights into the multidimensional nature of resilience in outpatient settings. The cross-sectional design sets the groundwork for future longitudinal investigations, highlighting the need for a holistic approach to understanding and promoting resilience.
    CONCLUSIONS: This study holds immediate implications for participants and their communities. It underscores the adaptive capacities and coping mechanisms prevalent in the outpatient population by revealing commendable resilience levels. This insight enhances individuals\' psychological and emotional well-being, contributing positively to the overall resilience and communal strength. Additionally, this study sheds light on how resilience among community members in Saudi Arabia relates to international advanced nursing communities, providing insight into their work.
    UNASSIGNED: Patients who have received outpatient services in the past 6 months were purposively chosen to ensure a diverse representation across age, gender and socio-economic backgrounds in this study.
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  • 文章类型: Journal Article
    基于行为测量的护理(MBC)可以改善患者的治疗效果,并且作为识别和减轻心理健康治疗中潜在差异的关键学习卫生系统(LHS)工具也得到了发展。然而,关于在安全网设置中远程行为MBC的吸收知之甚少,或远程MBC实施中可能出现的差异。
    本研究使用电子健康记录数据来研究远程MBC症状测量工具在三个成人门诊精神病诊所实施的前6个月中,诊所和患者水平的完成率的变化。安全网卫生系统。还使用在三个站点之一的重复调查来衡量提供者报告的MBC采用障碍。
    在收到MBC测量请求的1219名患者中,完成至少一项因诊所而异的措施的摄取:普通成人诊所,38%(n=696人中的262人);物质使用诊所,28%(n=73/265);过渡诊所,17%(258的n=44)。与白人患者相比,黑人和葡萄牙或巴西患者的摄取较低。老年患者的摄取也较低。西班牙语护理与患者水平的低得多有关。在临床调整后,患者水平的摄取差异仍然存在,心理健康诊断,和发送的度量请求数。提供商将就诊时间和工作流程中的带宽作为与患者讨论MBC结果的最大一致障碍。
    患者和临床水平的MBC摄取存在显著差异。从LHS数据基础设施的角度来看,安全网卫生系统可能需要解决对适应MBC的可能方法的需求,以更好地适应其人群和临床需求,或确定有针对性的实施策略,以缩小已确定的差异人群的数据差距。
    UNASSIGNED: Behavioral measurement-based care (MBC) can improve patient outcomes and has also been advanced as a critical learning health system (LHS) tool for identifying and mitigating potential disparities in mental health treatment. However, little is known about the uptake of remote behavioral MBC in safety net settings, or possible disparities occurring in remote MBC implementation.
    UNASSIGNED: This study uses electronic health record data to study variation in completion rates at the clinic and patient level of a remote MBC symptom measure tool during the first 6 months of implementation at three adult outpatient psychiatry clinics in a safety net health system. Provider-reported barriers to MBC adoption were also measured using repeated surveys at one of the three sites.
    UNASSIGNED: Out of 1219 patients who were sent an MBC measure request, uptake of completing at least one measure varied by clinic: General Adult Clinic, 38% (n = 262 of 696); Substance Use Clinic, 28% (n = 73 of 265); and Transitions Clinic, 17% (n = 44 of 258). Compared with White patients, Black and Portuguese or Brazilian patients had lower uptake. Older patients also had lower uptake. Spanish language of care was associated with much lower uptake at the patient level. Significant patient-level disparities in uptake persisted after adjusting for the clinic, mental health diagnoses, and number of measure requests sent. Providers cited time within visits and bandwidth in their workflow as the greatest consistent barriers to discussing MBC results with patients.
    UNASSIGNED: There are significant disparities in MBC uptake at the patient and clinic level. From an LHS data infrastructure perspective, safety net health systems may need to address the need for possible ways to adapt MBC to better fit their populations and clinical needs, or identify targeted implementation strategies to close data gaps for the identified disparity populations.
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  • 文章类型: Journal Article
    几乎没有经验证据支持混合精神病治疗的有效性,定义为通过电话组合提供的护理,视频会议,和亲自访问。作者旨在调查与门诊候诊者组相比,混合精神病护理的有效性。用患者报告的结果测量(PROMs)进行评估。
    参与者是从成人精神病学诊所候补名单中招募的,最常见的主要诊断是单相抑郁症,广泛性焦虑障碍,和双相情感障碍。患者(N=148)被随机分配到两个等待名单组之一,在治疗开始前完成一次或每月完成PROM。PROM用于评估抑郁症状(患者健康问卷-9[PHQ-9]),焦虑(广义焦虑症-7[GAD-7]),和日常心理功能(简短调整量表-6[BASE-6])。患者的措施用平均值进行描述性总结,中位数,和SDs,然后使用Kruskal-Wallis检验进行比较;计算相关效应大小。将在不同时期(N=272)接受混合精神病治疗的患者的PROM得分与等待名单组的得分进行比较。
    对参与混合护理的患者进行的胎膜早破评估表明,与等待组相比,症状严重程度有了显著改善,无论患者在等待名单上完成的PROM数量如何.在混合护理和候诊者群体之间,PHQ-9评分的效应大小中等(d=0.66);GAD-7评分(d=0.46)和BASE-6评分(d=0.45)的效应大小较小.
    这些发现表明了混合护理的临床有效性,并且PROM可用于评估这种有效性。
    UNASSIGNED: Little empirical evidence exists to support the effectiveness of hybrid psychiatric care, defined as care delivered through a combination of telephone, videoconferencing, and in-person visits. The authors aimed to investigate the effectiveness of hybrid psychiatric care compared with outpatient waitlist groups, assessed with patient-reported outcome measures (PROMs).
    UNASSIGNED: Participants were recruited from an adult psychiatry clinic waitlist on which the most common primary diagnoses were unipolar depression, generalized anxiety disorder, and bipolar disorder. Patients (N=148) were randomly assigned to one of two waitlist groups that completed PROMs once or monthly before treatment initiation. PROMs were used to assess symptoms of depression (Patient Health Questionnaire-9 [PHQ-9]), anxiety (Generalized Anxiety Disorder-7 [GAD-7]), and daily psychological functioning (Brief Adjustment Scale-6 [BASE-6]). Patient measures were summarized descriptively with means, medians, and SDs and then compared by using the Kruskal-Wallis test; associated effect sizes were calculated. PROM scores for patients who received hybrid psychiatric treatment during a different period (N=272) were compared with scores of the waitlist groups.
    UNASSIGNED: PROM assessments of patients who engaged in hybrid care indicated significant improvements in symptom severity compared with the waitlist groups, regardless of the number of PROMs completed while patients were on the waitlist. Between the hybrid care and waitlist groups, the effect size for the PHQ-9 score was moderate (d=0.66); effect sizes were small for the GAD-7 (d=0.46) and BASE-6 (d=0.45) scores.
    UNASSIGNED: The findings indicate the clinical effectiveness of hybrid care and that PROMs can be used to assess this effectiveness.
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  • 文章类型: Journal Article
    目的:在抗逆转录病毒治疗的进展和,随着艾滋病毒感染者的特点向人口老龄化发展,了解治疗中断的原因变得至关重要。该研究的目的是确定抗逆转录病毒治疗中断12年的原因的变化。其次,比较年度抗逆转录病毒方案停药率和相关因素。
    方法:我们使用来自HIV感染者的数据进行了分析,这些人正在接受抗逆转录病毒治疗并因任何原因停止治疗。该研究包括从2010年1月至2021年12月访问门诊医院药房的HIV感染者。分析区分了两个时期:2010-2015年和2016-2021年。停止抗逆转录病毒治疗的原因遵循瑞士队列描述的分类。在这项研究的背景下,值得注意的是,本文中的术语“中断”将始终用于指代转换或停止抗逆转录病毒治疗的行为。为了检查与抗逆转录病毒治疗停止相关的因素,我们使用Kaplan-Meier方法和Cox比例模型。
    结果:我们包括789名艾滋病毒感染者,主要是男性(81,5%)。停药的主要原因是临床决定(50.2%),其次是不良反应(37.9%)。专注于临床决策,我们观察到趋势变化,从分析期的前一部分的抗逆转录病毒治疗方案简化(56.1%)到后半部分的治疗优化(53.6%).此外,与停止抗逆转录病毒治疗有统计学意义的因素是HIV患者≥50岁(HR1.60;95CI1.25-2.04),停药后单片治疗方案(HR1.49;95CI1.06-2.11)和抗逆转录病毒药物类别。
    结论:在过去的12年中,抗逆转录病毒治疗中断的主要原因发生了变化,目前治疗优化是主要原因。与其他抗逆转录病毒药物类别相比,以整合酶抑制剂为基础的方案和单片方案策略不太可能被停用。由于疗效,允许更好的临床管理,特别是在艾滋病毒感染者≥50岁并有合并症。
    OBJECTIVE: In the context of the advancement of antiretroviral therapy and, as the characteristics of people living with HIV progress toward an aging population, understanding the causes of treatment interruption becomes crucial. The aim of the study was to determine the change in reasons for antiretroviral treatment discontinuation for 12 years. Secondarily, compare annual antiretroviral regimen discontinuation rate and factors associated.
    METHODS: We conducted an analysis using data from people living with HIV who were receiving antiretroviral therapy and discontinued it for any reason. The study included people with HIV infection who visited an outpatient hospital pharmacy clinic from January 2010 to December 2021. Two periods were differentiated for the analysis: 2010-2015 and 2016-2021. The reasons for antiretroviral treatment discontinuation followed classification described by Swiss cohort. In the context of this study, it is pertinent to note that the term \'interruption\' will be consistently used in this article to refer to the act of switching or stopping antiretroviral treatment. To examine factors associated with antiretroviral therapy discontinuation, we utilized Kaplan-Meier methods and Cox proportional models.
    RESULTS: We included 789 people living with HIV, predominantly male (81,5%). The main reason for discontinuation was clinical decision (50.2%) followed by adverse effects (37.9%). Focusing on clinical decision, we observed a trend change that went from antiretroviral treatment simplification regimen (56.1%) in the first part of the period analyzed to the therapeutic optimization (53.6%) in the second half. Furthermore, factors that were statistically significantly associated with antiretroviral treatment discontinuation were people with HIV ≥50 years (HR 1.60; 95%CI 1.25-2.04), post-discontinuation single-tablet regimen (HR 1.49; 95%CI 1.06-2.11) and antiretroviral drug classes.
    CONCLUSIONS: Over the 12 years there has been a change in the main cause of antiretroviral treatment discontinuation, currently therapeutic optimization being the main reason. Integrase inhibitors-based regimens and singletablet regimen strategies were less likely to be discontinued than others antiretroviral drug classes, allowing for better clinical management due to the efficacy profile, especially in people living with HIV ≥50 years with comorbidities.
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  • 文章类型: Journal Article
    背景:面对COVID-19疫情,大多数医疗机构被迫关闭或搬迁。非COVID-19患者可能会受到附带影响。
    方法:分析了西岸地区部分巴勒斯坦政府医院的诊所和手术室记录。
    结果:患者就诊次数减少了49%至90%,耳鼻喉(ENT),泌尿科,儿科诊所受影响最大。该中心(具有独立决策)的运营数量减少了7.1%至23.4%,但是在北方和南方(遵循集中选择),下降幅度为19.6%至91.8%。
    结论:COVID-19影响门诊就诊。大流行影响了一些服务,但西岸医院能够提供正常的产科和妇科治疗,并帮助需要初级或中级手术的患者。
    BACKGROUND: Confronting the COVID-19 epidemic forced the closure or relocation of the majority of health facilities. It is likely that non-COVID-19 patients suffered collateral effects.
    METHODS: The clinic and operating room records were analyzed at selected Palestinian government hospitals in the West Bank region.
    RESULTS: The reduction in patient clinic visits varied from 49% to 90%, with Ear-Nose-Throat (ENT), urology, and pediatric clinics being the most affected. The reduction in operation numbers in the center (which had independent decision-making) ranged from 7.1% to 23.4%, but in the north and south (which followed centralized choices), the reduction ranged from 19.6% to 91.8%.
    CONCLUSIONS: COVID-19 affected outpatient visits. The pandemic affected some services, but West Bank hospitals were able to provide normal obstetric and gynecological treatments and help patients who needed primary or intermediate surgery.
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  • 文章类型: Journal Article
    背景:在2019年冠状病毒病(COVID-19)防控中积累的经验和管理措施的应用通常取决于对流行强度的主观判断,防控管理质量参差不齐。本研究旨在开发门诊患者COVID-19感染的新型风险管理系统,能够根据估计的感染风险提供准确和分层的控制。
    方法:使用自回归综合移动平均模型(ARIMA)估计感染风险。首都医科大学宣武医院门诊患者流感样疾病(ILI)的每周监测数据以及2021年和22年从百度指数下载的百度搜索数据用于拟合ARIMA模型。通过确定平均绝对百分比误差(MAPE)来评估该模型估计感染风险的能力,使用Delphi过程就分层感染控制措施达成共识。COVID-19控制措施是通过审查公布的法规来选择的,文件和指南。确定了低风险期和高风险期的表面消毒和个人防护建议,这些建议是根据预测结果实施的。
    结果:ARIMA模型为ILI和搜索引擎数据提供了精确的估计。这些数据集的20周滚动预测的MAPE分别为13.65%和8.04%,分别。基于这两个风险水平,分级感染预防方法为个人防护和消毒提供了指导。还根据ARIMA结果建立了升级或降低感染预防策略的标准。
    结论:这些创新方法,以及ARIMA模型,对与COVID-19感染患者密切接触的医护人员表现出有效的感染保护,节省了维持高水平感染预防措施和加强呼吸道感染控制的近41%的成本。
    BACKGROUND: Application of accumulated experience and management measures in the prevention and control of coronavirus disease 2019 (COVID-19) has generally depended on the subjective judgment of epidemic intensity, with the quality of prevention and control management being uneven. The present study was designed to develop a novel risk management system for COVID-19 infection in outpatients, with the ability to provide accurate and hierarchical control based on estimated risk of infection.
    METHODS: Infection risk was estimated using an auto regressive integrated moving average model (ARIMA). Weekly surveillance data on influenza-like-illness (ILI) among outpatients at Xuanwu Hospital Capital Medical University and Baidu search data downloaded from the Baidu Index in 2021 and 22 were used to fit the ARIMA model. The ability of this model to estimate infection risk was evaluated by determining the mean absolute percentage error (MAPE), with a Delphi process used to build consensus on hierarchical infection control measures. COVID-19 control measures were selected by reviewing published regulations, papers and guidelines. Recommendations for surface sterilization and personal protection were determined for low and high risk periods, with these recommendations implemented based on predicted results.
    RESULTS: The ARIMA model produced exact estimates for both the ILI and search engine data. The MAPEs of 20-week rolling forecasts for these datasets were 13.65% and 8.04%, respectively. Based on these two risk levels, the hierarchical infection prevention methods provided guidelines for personal protection and disinfection. Criteria were also established for upgrading or downgrading infection prevention strategies based on ARIMA results.
    CONCLUSIONS: These innovative methods, along with the ARIMA model, showed efficient infection protection for healthcare workers in close contact with COVID-19 infected patients, saving nearly 41% of the cost of maintaining high-level infection prevention measures and enhancing control of respiratory infections.
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  • 文章类型: Journal Article
    目的:确定门诊头痛的诊断和治疗模式,重点是国际头痛疾病分类(ICHD)标准的文档。
    方法:回顾性队列数据是从18-35岁的成年人的电子病历中收集的,这些人被送到中西部的住院医师家庭医疗门诊诊所,美国,2015年至2016年期间出现新的或恶化的头痛。诊断代码用于总结头痛的总体性质和患病率。对30例伴有和不伴有先兆和紧张型头痛(TTH)的偏头痛(MGH)患者的随机子集进行了审查,以确定记录了五个可能的ICHD标准中的多少。人口统计学/临床特征,ICHD标准,药物的数量和类型,和医疗保健利用(成像,初级和急诊科护理)在初次就诊后的一年内进行了总结,并比较了头痛类型。
    结果:研究期间有716名独特患者(414MGH,227个未指明的头痛,75TTH,或其他)。记录了总共两名患者的完整ICHD标准。有部分文件(例如,可能的五个中的一个到四个)占TTH的30%,63%的MGH无先兆,77%的MGH具有先兆(p<0.05)。在头痛类型中,患者在一年内平均服用2.3至3.3种药物,MGH患者通常会尝试更多的药物(有先兆的患者最多服用8种,没有先兆的患者最多服用12种)。几乎所有患者都服用了堕胎或抢救药物;50%的MGH有先兆,66.7%的MGH无先兆,53.3%。非药物干预的处方较少:33.3%的TTH患者和3.3%的MGH类型的组合(p<0.05)。与TTH相比,有先兆(ED就诊)和无先兆(临床就诊)的MGH患者的医疗保健利用率最高(p<0.001)。
    结论:与头痛相关的文档通常不完整,这可能会限制诊断之间的解释和关联,处方模式,和医疗保健利用。未来的研究应该评估使用基于电子病历(EMR)的模板来改进文档,需要在当地进行更详细的研究,以确定治疗是否,包括使用非药物和预防性治疗方法,是最优的。
    OBJECTIVE: To determine headache diagnosis and treatment patterns in the outpatient setting, focusing on documentation of the International Classification of Headache Disorders (ICHD) criteria.
    METHODS: Retrospective cohort data were collected from electronic medical records of adults aged 18-35 who presented to resident-staffed family medicine outpatient clinics in the Midwest, USA, for a new or worsening headache between 2015 and 2016. Diagnosis codes were used to summarize the overall nature and prevalence of headaches. A random subset of 30 patients each for migraine headache (MGH) with and without aura and tension-type headache (TTH) were reviewed to determine how many of the five possible ICHD criteria were documented. Demographics/clinical characteristics, ICHD criteria, number and type of medications, and healthcare utilization (imaging, primary and emergency department care) through one year following the initial visit were summarized and compared across headache types.
    RESULTS: There were 716 unique patients during the study period (414 MGH, 227 unspecified headaches, 75 TTH, or others). Complete ICHD criteria were documented for two patients in total. There was partial documentation (e.g., one to four of the possible five) for 30% of TTH, 63% of MGH without aura, and 77% of MGH with aura (p<0.05). Across headache types, patients were prescribed an average of 2.3 to 3.3 medications over one year, with MGH patients generally trying more medications (up to eight for those with aura and up to 12 for those without). Abortive or rescue medications were prescribed to nearly all patients; prophylactics were prescribed for 50% of MGH with aura, 66.7% of MGH without aura, and 53.3%. Non-pharmacologic interventions were less prescribed: 33.3% of TTH patients and 3.3% of MGH types combined (p<0.05). Healthcare utilization was highest for MGH with aura (ED visits) and without aura (clinic visits) patients compared to TTH (p<0.001).
    CONCLUSIONS: Headache-related documentation is often incomplete, which may limit interpretation and associations between diagnoses, prescribing patterns, and healthcare utilization. Future studies should evaluate the use of electronic medical records (EMR)-based templates to improve documentation, and additional detailed studies are needed in the local setting to determine whether treatment, including the use of non-pharmacologic and prophylactic methods of treatment, is optimal.
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  • 文章类型: Journal Article
    背景:在抗逆转录病毒疗法的发展背景下,随着艾滋病毒感染者向人口老龄化发展的特征,了解治疗中断的原因变得至关重要。该研究的目的是确定抗逆转录病毒治疗中断12年的原因的变化。其次,比较年度抗逆转录病毒方案停药率和相关因素。
    方法:我们使用来自HIV感染者的数据进行了分析,这些人正在接受抗逆转录病毒治疗并因任何原因停止治疗。该研究包括从2010年1月至2021年12月访问门诊医院药房的HIV感染者。分析区分了两个时期:2010-2015年和2016-2021年。停止抗逆转录病毒治疗的原因遵循瑞士队列描述的分类。在这项研究的背景下,值得注意的是,术语“中断”与“中断”同义。术语“停药”将在本文中始终用于指代转换或停止抗逆转录病毒治疗的行为。为了检查与抗逆转录病毒治疗停止相关的因素,我们使用Kaplan-Meier方法和Cox比例模型。
    结果:我们包括789名艾滋病毒感染者,以男性为主(81.5%)。停药的主要原因是临床决定(50.2%),其次是不良反应(37.9%)。专注于临床决策,我们观察到趋势变化,从分析期的前半部分的抗逆转录病毒治疗方案简化(56.1%)到后半部分的治疗方案优化(53.6%).此外,与停止抗逆转录病毒治疗有统计学意义的因素是HIV患者≥50岁(HR1.60;95CI1.25-2.04),停药后单片治疗方案(HR1.49;95CI1.06-2.11)和抗逆转录病毒药物类别。
    结论:在过去的12年里,抗逆转录病毒治疗中断的主要原因发生了变化,目前治疗优化是主要原因。与其他抗逆转录病毒药物类别相比,以整合酶抑制剂为基础的方案和单片方案策略不太可能停用。由于疗效,允许更好的临床管理,特别是在艾滋病毒感染者≥50岁并有合并症。
    BACKGROUND: In the context of the advancement of antiretroviral therapy and as the characteristics of people living with HIV progress toward an ageing population, understanding the causes of treatment interruption becomes crucial. The aim of the study was to determine the change in reasons for antiretroviral treatment discontinuation for 12 years. Secondarily, compare annual antiretroviral regimen discontinuation rate and factors associated.
    METHODS: We conducted an analysis using data from people living with HIV who were receiving antiretroviral therapy and discontinued it for any reason. The study included people with HIV infection who visited an outpatient hospital pharmacy clinic from January 2010 to December 2021. Two periods were differentiated for the analysis: 2010-2015 and 2016-2021. The reasons for antiretroviral treatment discontinuation followed classification described by Swiss cohort. In the context of this study, it is pertinent to note that the term \"discontinuation\" is employed synonymously with \"interruption\". The term \"discontinuation\" will be consistently used in this article to refer to the act of switching or stopping antiretroviral treatment. To examine factors associated with antiretroviral therapy discontinuation, we utilised Kaplan-Meier methods and Cox proportional models.
    RESULTS: We included 789 people living with HIV, predominantly male (81.5%). The main reason for discontinuation was clinical decision (50.2%) followed by adverse effects (37.9%). Focusing on clinical decision, we observed a trend change that went from antiretroviral treatment simplification regimen (56.1%) in the first part of the period analysed to the therapeutic optimisation (53.6%) in the second half. Furthermore, factors that were statistically significantly associated with antiretroviral treatment discontinuation were people with HIV≥50 years (HR 1.60; 95%CI 1.25-2.04), post-discontinuation single-tablet regimen (HR 1.49; 95%CI 1.06-2.11) and antiretroviral drug classes.
    CONCLUSIONS: Over the 12 years, there has been a change in the main cause of antiretroviral treatment discontinuation, currently therapeutic optimisation being the main reason. Integrase inhibitors-based regimens and single-tablet regimen strategies were less likely to be discontinued than others antiretroviral drug classes, allowing for better clinical management due to the efficacy profile, especially in people living with HIV≥50 years with comorbidities.
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