obstructive hydrocephalus

梗阻性脑积水
  • 文章类型: Case Reports
    早期识别和及时手术干预对于治疗引起梗阻性脑积水的巨大蛛网膜囊肿至关重要。就像一个17岁的男性案例所说明的那样。及时治疗可以缓解症状,预防神经系统并发症,确保受影响患者的良好结果。
    Early recognition and prompt surgical intervention are crucial in managing giant arachnoid cysts causing obstructive hydrocephalus, as illustrated in this case of a 17-year-old male. Timely treatment can alleviate symptoms and prevent neurologic complications, ensuring favorable outcomes in affected patients.
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  • 文章类型: Journal Article
    背景:颞角(TH)的压迫是罕见的情况,可导致颅内压升高,但对标准治疗尚无共识。这项研究的目的是对所报道的TH截留病例进行系统的文献回顾,并描述我们将侧脑室的内窥镜开窗入基底水箱的手术技术。
    方法:我们搜索了数据库Pubmed和Googlescholar,以找到所有报告截留TH和后续治疗病例的研究。此外,我们报告了两个示例性的内镜开窗术病例,并对我们的手术技术进行了分步描述.
    结果:29项研究共67例患者纳入分析。平均年龄36.5岁(SD±21.9),男女比例为1.5。TH截留的最常见原因是肿瘤手术后的手术后瘢痕形成(n=30),最常报道的治疗方式是内镜下TH开窗术(n=14).我们观察到内窥镜开窗术的使用随着时间的推移而增加。
    结论:被困TH是一种罕见的疾病,通常需要手术治疗。神经导航引导的内镜下将心室开窗入基底水箱似乎是安全的,高效,和无设备技术在过去几年中变得越来越重要。
    BACKGROUND: Entrapment of the temporal horn (TH) is rare condition that can lead to increased intracranial pressure, but there is no consensus on a standard treatment. The aim of this study was to conduct a systematic literature review of the reported cases of TH entrapment and describe our operative technique for endoscopic fenestrations of the lateral ventricle into the basal cisterns.
    METHODS: We searched the databases Pubmed and Google scholar to find all studies reporting cases of entrapped TH and the subsequent treatment. Additionally, we report two illustrative cases of endoscopic fenestration with a step-by-step description of our surgical technique.
    RESULTS: Twenty-nine studies with a total of 67 patients were included in the analysis. The mean age was 36.5 years (SD± 21.9), and the female-to-male ratio was 1.5. The most frequent cause of TH entrapment was post-surgical scarring after tumor surgery (n= 30), and the most commonly reported treatment modality was endoscopic fenestration of the TH (n = 14). We observed an increasing use of endoscopic fenestration over time.
    CONCLUSIONS: Entrapped TH is a rare condition often requiring surgical treatment. Neuronavigation-guided endoscopic fenestration of the ventricle into the basal cisterns appears to be a safe, efficient, and device-free technique that has gained importance over the past years.
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  • 文章类型: Case Reports
    引言脑积水是一种以脑室系统内脑脊液异常积聚为特征的疾病。它可以源于阻塞性和非阻塞性原因。妊娠会引起病理生理变化,可能会增加发生或恶化症状性脑积水的风险。然而,这方面的全面报道,特别是关于外科手术,保持稀缺。病例报告一名有反复头痛病史的年轻女性在怀孕开始时症状恶化。前三个月的磁共振成像(MRI)显示心室扩张增加,提示导水管狭窄引起的阻塞.在神经外科委员会会议上,讨论了治疗方案,考虑到可识别的障碍物,与怀孕相关的腹内压力升高,和心室分流功能障碍的风险。患者接受了内镜下第三脑室造瘘术(ETV),无并发症,导致症状缓解和成功怀孕。讨论由于对母亲和胎儿的风险增加,孕妇的神经外科手术很少见。然而,由合格的多学科团队执行时,它们可以带来积极的结果。在怀孕期间脑积水的情况下,ETV似乎是手术干预的可行替代方案,特别是当脑积水出现症状并被确定为阻塞性病因时,无论是现有分流患者还是新发展的脑积水患者。
    Introduction  Hydrocephalus is a condition characterized by the abnormal accumulation of cerebrospinal fluid within the brain\'s ventricular system. It can stem from obstructive and nonobstructive causes. Pregnancy introduces physiopathological changes that may heighten the risk of developing or worsening symptomatic hydrocephalus. Nevertheless, comprehensive reports on this aspect, especially regarding surgical interventions, remain scarce. Case Report  A young woman with a history of recurrent headaches experienced a worsening of her symptoms at the onset of her pregnancy. A magnetic resonance imaging (MRI) in the first trimester revealed increased ventricular dilation, indicating an obstructive cause due to aqueduct stenosis. During a neurosurgical board meeting, treatment options were discussed, considering the identifiable obstruction, the heightened intra-abdominal pressure associated with pregnancy, and the risk of ventricular shunt dysfunction. The patient underwent an endoscopic third ventriculostomy (ETV) without complications, leading to both symptom relief and a successful conclusion to the pregnancy. Discussion  Neurosurgical procedures in pregnant women are uncommon due to the increased risks to both the mother and the fetus. However, when performed by a qualified multidisciplinary team, they can lead to positive outcomes. In cases of hydrocephalus during pregnancy, ETV appears to be a viable alternative for surgical intervention, particularly when hydrocephalus becomes symptomatic and an obstructive cause is identified, whether in patients with existing shunts or those with newly developed hydrocephalus.
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  • 文章类型: Case Reports
    Galen动脉瘤畸形(VGAM)静脉是Markowski胚胎前脑正中静脉的罕见先天性动静脉瘘,导致其病理性扩张。如果不及时治疗,在新生儿期会导致多种严重的并发症,其中包括梗阻性脑积水。我们提供了一例6岁男性患者的病例报告,该患者患有严重的癫痫持续状态,并有VGAM和阻塞性脑积水的临床病史。通过MRI和MR血管造影诊断。脑积水在六个月大时通过脑室造口术治疗,而VGAM在患者4岁时接受了部分经动脉血管内栓塞。程序成功了,并且没有观察到明显的术后并发症。癫痫发作在稍后的时间点开始,并成功地用丙戊酸盐治疗。然而,由于患者父母降低了药物剂量,他们恢复了。患者给予适当剂量的新丙戊酸方案,他的父母报告没有进一步的癫痫发作。该病例报告强调对VGAM使用适当的产前和新生儿诊断方法,并探讨了与可能的特发性共病相关的病理及其并发症的多程序治疗方法的性质。即癫痫。
    The vein of Galen aneurysmal malformation (VGAM) is a rare congenital arteriovenous fistula of the embryonic median prosencephalic vein of Markowski, resulting in its pathological dilation. If left untreated, it can lead to multiple severe complications in the neonatal period, among which obstructive hydrocephalus. We present a case report of a six-year-old male patient with severe status epilepticus and a clinical history of VGAM and obstructive hydrocephalus, diagnosed via an MRI and an MR-angiography. The hydrocephalus was treated via a ventriculostomy at the age of six months, while the VGAM underwent a partial transarterial endovascular embolization when the patient was four years old. The procedures were successful, and there were no significant post-operative complications observed. The epileptic seizures began at a later point and were successfully medicated with valproate. However, they resumed due to a lowering of the medication dosage by the patient\'s parents. The patient was given a new valproic acid regimen with an appropriate dosage, and his parents reported no further seizures. This case report emphasizes the use of appropriate prenatal and neonatal diagnostic methods for VGAM and explores the nature of the multi-procedural therapy approach towards the pathology and its complications in relation to a possibly idiopathic co-pathology, namely epilepsy.
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  • 文章类型: Case Reports
    Lemierre综合征的特征是颈内静脉血栓性静脉炎和菌血症,主要来自厌氧生物。这种情况通常在最近的口咽感染后出现。年轻,健康人长期咽炎进展为败血症,肺炎,或侧颈僵硬应怀疑患有Lemierre综合征。识别颈内静脉血栓性静脉炎和在血液培养上发展厌氧性细菌生长通常用于确认诊断。治疗包括长期抗生素治疗,有时与抗凝药物一起使用。在这个案例报告中,我们描述了一名29岁男性结核分枝杆菌合并肺结核的独特病例,结核性脑膜炎,结核相关性急性缺血性卒中合并化脓性血栓性静脉炎.患者出现突然发作的感觉改变4小时。对大脑进行了磁共振成像,提示梗阻性脑积水伴脑室周围渗出.病人开始接受抗菌治疗,抗生素,抗凝剂,和全身性类固醇。患者出院时非常稳定。因此,至关重要的是,在提供及时和相关的诊断并推荐正确的治疗方案的同时,考虑这种非典型结核病表现的可能性。
    Lemierre\'s syndrome is characterized by internal jugular vein thrombophlebitis and bacteremia, primarily from anaerobic organisms. The condition usually arises after a recent oropharyngeal infection. Young, healthy people with prolonged pharyngitis that progresses into septicemia, pneumonia, or lateral neck stiffness should be suspected of having Lemierre\'s syndrome. Identifying internal jugular vein thrombophlebitis and developing anaerobic bacterial growth on blood culture are frequently used to confirm the diagnosis. Treatment consists of long-term antibiotic treatment, sometimes in conjunction with anticoagulant medication. In this case report, we describe the unique case of a 29-year-old male with Mycobacterium tuberculosis with pulmonary tuberculosis, tubercular meningitis, tuberculosis-related acute ischemic stroke with septic thrombophlebitis. The patient presented with sudden onset altered sensorium for 4 hours. Magnetic resonance imaging of the brain was done, which suggested obstructive hydrocephalus with periventricular ooze. The patient was started on antibacillary treatment, antibiotics, anticoagulants, and systemic steroids. The patient was vitally stable when he was discharged. Therefore, it is crucial to consider the likelihood of such atypical tuberculosis presentations while providing a prompt and relevant diagnosis and recommending the right course of therapy.
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  • 文章类型: Journal Article
    背景:孤立的脑毛霉菌病在免疫功能正常的成年人中很少见,据报道仅与阻塞性脑积水有关。
    方法:这里,作者报告了一例继发于中枢神经系统毛霉菌病的梗阻性脑积水,但没有其他系统或犀牛眶受累,并对其进行了技术手术治疗。一个23岁的年轻人,被监禁,有静脉(IV)药物使用史的免疫功能正常的患者出现晕厥。尽管临床和影像学检查结果未能阐明感染性病理学,内窥镜检查显示第三脑室水平有阻塞性肿块病变,which,关于微生物测试,被证实为根霉真菌性脑室炎。围手术期脑脊液改道,内镜下第三脑室造瘘术,内镜活检技术,患者结果,并在这里回顾了文献。该患者接受鞘内注射和静脉注射两性霉素B,然后进行口服抗真菌治疗,目前仍处于缓解状态。
    结论:患者对孤立性脑毛霉菌病的独特表现和诊断表明,这种病原体是免疫功能正常的成年患者的脑室炎和阻塞性脑积水的原因,即使在神经影像学上没有感染性后遗症。
    BACKGROUND: Isolated cerebral mucormycosis is rare in immunocompetent adults and is only sparsely reported to be associated with obstructive hydrocephalus.
    METHODS: Here, the authors report a case of obstructive hydrocephalus secondary to central nervous system mucormycosis without other systems or rhino-orbital involvement and its technical surgical management. A 23-year-old, incarcerated, immunocompetent patient with history of intravenous (IV) drug use presented with syncope. Although clinical and radiographic findings failed to elucidate an infectious pathology, endoscopy revealed an obstructive mass lesion at the level of the third ventricle, which, on microbiological testing, was confirmed to be Rhizopus fungal ventriculitis. Perioperative cerebrospinal fluid diversion, endoscopic third ventriculostomy, endoscopic biopsy technique, patient outcomes, and the literature are reviewed here. The patient received intrathecal and IV amphotericin B followed by a course of oral antifungal treatment and currently remains in remission.
    CONCLUSIONS: The patient\'s unique presentation and diagnosis of isolated cerebral mucormycosis reveal this pathogen as a cause of ventriculitis and obstructive hydrocephalus in immunocompetent adult patients, even in the absence of infectious sequelae on neuroimaging.
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  • 文章类型: Case Reports
    发育静脉异常(DVA)是相关实质的静脉引流,通常无症状。然而,位于导水管附近的DVA可通过阻断脑脊液的流动而导致梗阻性脑积水。我们描述了由于DVA继发的导水管狭窄引起的罕见梗阻性脑积水。一名43岁的男子在举重训练中突然出现双侧颞部疼痛。使用3特斯拉扫描仪,进行头颅磁共振成像(MRI),发现脑积水,侧脑室和第三脑室轻度增大。磁敏感加权成像和对比后MRI显示,来自双侧丘脑的DVA在通向Galen静脉的引流路线上缩小了渡槽的孔口。我们假设在举重训练期间施加的力可能导致异常静脉扩张,导致他的症状。对相关英语文献的回顾仅产生了19例因DVA引起的导水管狭窄。与这些案例相比,在我们的病例中,症状持续时间极短,因为患者有在普通计算机断层扫描中检测到的脑室增宽病史,并根据DVA的特征性发现:caputmedusae外观迅速诊断.
    A developmental venous anomaly (DVA) is a venous drainage of the associated parenchyma that is normally asymptomatic. However, a DVA located adjacent to the aqueduct can cause obstructive hydrocephalus by blocking the flow of cerebrospinal fluid. We describe a rare case of obstructive hydrocephalus due to aqueductal stenosis secondary to a DVA. A 43-year-old man presented with sudden bilateral temporal pain during weight training. Using a 3-Tesla scanner, cranial magnetic resonance imaging (MRI) was performed, and hydrocephalus was found with mild enlargement of the lateral and third ventricles. Susceptibility-weighted imaging and postcontrast MRI revealed that the DVA from the bilateral thalami narrowed the orifice of the aqueduct on its drainage route towards the vein of Galen. We assumed that force exerted during weight training may have caused dilation of the anomalous veins, leading to his symptom. A review of the relevant English-language literature yielded only 19 cases of aqueductal stenosis due to DVA. In comparison to these cases, the duration of symptom in our case was extremely short because the patient had a history of ventriculomegaly detected on plain computed tomography and was diagnosed quickly based on the characteristic finding of DVA: the caput medusae appearance.
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  • 文章类型: Editorial
    暂无摘要。
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  • 文章类型: Journal Article
    背景:血管周围空间(PVSs)是脑实质中充满间质液的小脑血管周围的空间。PVSs的大量扩大被称为“巨大的管状血管周围空间”(GTPVSs),根据它们的本地化可以分为三种类型。这些病变很罕见,主要无症状,通常最初被误解为囊性肿瘤的形成。然而,有报道的几个病例中,GTPVSs由于其大小而引起神经系统症状,质量效应,和位置,最终导致梗阻性脑积水,需要神经外科干预。这里介绍了GTPVS的三种不同的临床表现。
    方法:这里,作者观察到一个无症状的1型GTPVS病例和两个有症状的3型GTPVS病例,一个引起局部肿块效应,另一个引起脑积水。
    结论:GTPVSs大多为无症状性病变。没有症状的患者应密切监测,活检是不鼓励的。由GTPVS引起的脑积水需要手术干预。在这些情况下,第三脑室造瘘术,分流植入,或直接囊肿开窗术是手术选择。对于出现局部肿块效应症状的患者,对潜在的神经外科干预进行全面评估势在必行.建议在3型GTPVS中跟进,特别是在未经治疗的情况下。鉴于GTPVS的频率不高,神经外科治疗和后续随访的最终指南仍然难以捉摸。
    BACKGROUND: Perivascular spaces (PVSs) are spaces in brain parenchyma filled with interstitial fluid surrounding small cerebral vessels. Massive enlargements of PVSs are referred to as \"giant tumefactive perivascular spaces\" (GTPVSs), which can be classified into three types depending on their localization. These lesions are rare, predominantly asymptomatic, and often initially misinterpreted as cystic tumor formations. However, there are several reported cases in which GTPVSs have induced neurological symptoms because of their size, mass effect, and location, ultimately leading to obstructive hydrocephalus necessitating neurosurgical intervention. Presented here are three diverse clinical presentations of GTPVS.
    METHODS: Here, the authors observed an asymptomatic case of type 1 GTPVS and two symptomatic cases of type 3 GTPVS, one causing local mass effect and the other hydrocephalus.
    CONCLUSIONS: GTPVSs are mostly asymptomatic lesions. Patients without symptoms should be closely monitored, and biopsy is discouraged. Hydrocephalus resulting from GTPVS necessitates surgical intervention. In these cases, third ventriculostomy, shunt implantation, or direct cyst fenestration are surgical options. For patients presenting with symptoms from localized mass effect, a thorough evaluation for potential neurosurgical intervention is imperative. Follow-up in type 3 GTPVS is recommended, particularly in untreated cases. Given the infrequency of GTPVS, definitive guidelines for neurosurgical treatment and subsequent follow-up remain elusive.
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  • 文章类型: Case Reports
    室管膜下瘤是脑室的良性肿瘤,从脑室壁生长到脑内的脑脊液空间,阻塞脑脊液的流动并引起梗阻性脑积水。据估计,室管膜瘤占所有颅内肿瘤的0.2%至0.7%。它们最常见于第四脑室(50-60%)和侧脑室(30-40%)。我们介绍一个50岁的病人,以前被诊断患有脑室内过程,在我们的诊所住院。在神经系统检查中,病人很合作,Bradylalic,和bradypsychic,右偏瘫,姿势和平衡障碍,偶尔括约肌性尿失禁。增强MRI描述了左心室内肿瘤,在左侧脑室的额角具有均匀的外观,最大直径为50毫米,底部插入门罗孔的相邻室管膜,这决定了梗阻性脑积水。实现了左心室脑肿瘤的完全切除。组织病理学分析显示室管膜下瘤。术后恢复缓慢良好,神经明显改善。在三个月随访的神经系统检查中,患者的右偏瘫和非系统平衡障碍得到改善。进行了对比增强CT扫描,突出显示与手术肿瘤相对应的左额叶后遗症低密度,左心室扩大,无活动性脑积水,没有肿瘤复发的迹象.在六个月的随访中,临床放射学发现与三个月的随访结果一致。室管膜下瘤是生长缓慢的(1级)肿瘤,通常预后良好。不幸的是,由于它们的解剖水平,可能会出现多种并发症,由梗阻性脑积水并发症引起,如认知功能障碍和失禁。肿瘤切除应该完成,成功的手术对每个神经外科医生来说都是一个挑战。
    Subependymomas are benign tumors of the ventricles that grow from the ventricular wall into the cerebrospinal fluid spaces within the brain, obstructing the flow of the cerebrospinal fluid and causing obstructive hydrocephalus. It is estimated that ependymomas represent between 0.2% and 0.7% of all intracranial tumors. They arise most frequently in the fourth ventricle (50-60%) and the lateral ventricles (30-40%). We present the case of a 50-year-old patient, previously diagnosed with an intraventricular process, admitted in our clinic. At neurological examination, the patient was cooperative, bradylalic, and bradypsychic, with right hemiparesis, postural and balance disorders, and occasionally sphincteric incontinence. MRI with contrast described a left intraventricular tumor, in the frontal horn of the left lateral ventricle with homogeneous appearance, with a maximum diameter of 50 mm and base of insertion at the adjacent ependyma of the foramen of Monro, which determined obstructive hydrocephalus. Total resection of the left intraventricular cerebral tumor was achieved. Histopathological analysis revealed a subependymoma. Postoperative recovery was slowly favorable, with significant neurological improvement. At neurological examination at three-month follow-up, the patient\'s right hemiparesis and unsystematized balance disorders improved. A contrast-enhanced CT scan was performed, highlighting left frontal sequelae hypodensity corresponding to the operated tumor, enlarged left lateral ventricle without active hydrocephalus, and no sign of tumor recurrence. At six-month follow-up, clinico-radiologic findings coincide with those from three-month follow-up. Subependymomas are slow-growing (grade 1) tumors and generally have a favorable prognosis. Unfortunately, due to their anatomical level, multiple complications can arise, caused from obstructive hydrocephalus complications, such as cognitive dysfunction and incontinence. Tumor resection should be complete, a successful operation being a challenge for every neurosurgeon.
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