PDF(Pubmed)
Abstract：
Lemierre\'s syndrome is characterized by internal jugular vein thrombophlebitis and bacteremia, primarily from anaerobic organisms. The condition usually arises after a recent oropharyngeal infection. Young, healthy people with prolonged pharyngitis that progresses into septicemia, pneumonia, or lateral neck stiffness should be suspected of having Lemierre\'s syndrome. Identifying internal jugular vein thrombophlebitis and developing anaerobic bacterial growth on blood culture are frequently used to confirm the diagnosis. Treatment consists of long-term antibiotic treatment, sometimes in conjunction with anticoagulant medication. In this case report, we describe the unique case of a 29-year-old male with Mycobacterium tuberculosis with pulmonary tuberculosis, tubercular meningitis, tuberculosis-related acute ischemic stroke with septic thrombophlebitis. The patient presented with sudden onset altered sensorium for 4 hours. Magnetic resonance imaging of the brain was done, which suggested obstructive hydrocephalus with periventricular ooze. The patient was started on antibacillary treatment, antibiotics, anticoagulants, and systemic steroids. The patient was vitally stable when he was discharged. Therefore, it is crucial to consider the likelihood of such atypical tuberculosis presentations while providing a prompt and relevant diagnosis and recommending the right course of therapy.
摘要：
Lemierre综合征的特征是颈内静脉血栓性静脉炎和菌血症，主要来自厌氧生物。这种情况通常在最近的口咽感染后出现。年轻,健康人长期咽炎进展为败血症，肺炎,或侧颈僵硬应怀疑患有Lemierre综合征。识别颈内静脉血栓性静脉炎和在血液培养上发展厌氧性细菌生长通常用于确认诊断。治疗包括长期抗生素治疗，有时与抗凝药物一起使用。在这个案例报告中,我们描述了一名29岁男性结核分枝杆菌合并肺结核的独特病例，结核性脑膜炎,结核相关性急性缺血性卒中合并化脓性血栓性静脉炎.患者出现突然发作的感觉改变4小时。对大脑进行了磁共振成像，提示梗阻性脑积水伴脑室周围渗出.病人开始接受抗菌治疗,抗生素,抗凝剂,和全身性类固醇。患者出院时非常稳定。因此,至关重要的是，在提供及时和相关的诊断并推荐正确的治疗方案的同时，考虑这种非典型结核病表现的可能性。
