背景:中国儿童缺乏心血管磁共振(心脏MR)参考范围。
目的:在中国健康儿童队列中建立特定年龄和性别的心脏MR参数参考范围。
方法:回顾性。
方法:一百九十六名健康儿童(平均年龄9.5±3.6岁,111男孩)。
■1.5T;平衡稳态自由进动。
结果:双心室容积和射血分数(EF),左心房(LA)容积,右心房(RA)面积,左心室(LV)质量和厚度,主动脉根部(AR),测量主肺动脉(MPA)尺寸。在年龄组和性别之间比较参数。参数和年龄之间的关系,身体质量指数(BMI)和体表面积(BSA)进行了调查。
方法:独立样本t检验;皮尔逊相关性。P值<0.05被认为是统计学上显著的。
结果:一般来说,男孩表现出更大的左心室容积绝对测量值(舒张末期:94.4±29.5vs.81.3±31.0mL),LA容积(舒张末期:42.6±13.4vs.38.0±13.3mL),RA面积(舒张末期:11.6±2.5vs.10.8±2.6cm2),低压厚度(基础:4.4±1.1vs.3.8±0.9mm),AR尺寸(环形:16.3±2.7与15.0±2.8mm),和MPA尺寸(14.3±2.3vs.13.1±2.4mm)比女孩多。然而,当测量值归一化为BSA时,未观察到这些差异(LV体积:75.3±11.7vs.71.9±12.3mL/m2,P=0.052;LA体积:34.8±8.9vs.34.5±7.6mL/m2,P=0.783;RA面积:9.7±2.3。10.2±2.3cm2/m2,P=0.107;LV厚度:3.6±0.7vs.3.6±0.9mm/m2,P=0.990;AR:13.6±2.7vs.14.3±3.4mm/m2,P=0.108;MPA:11.9±2.3vs.12.4±2.4mm/m2,P=0.118)。男孩的RV容量更大(舒张末期:98.7±33.5vs.82.7±33.1mL)和左心室质量(52.6±20.2vs.41.4±16.0g)与女孩相比,无论这些值是否针对BSA进行索引。此外,年龄之间有显著的关联,BMI,和具有双心室容积的BSA,洛杉矶卷,RA区,低压质量和厚度,男孩和女孩的AR和MPA维度。
结论:本研究建议中国儿童的参考范围为1.5T。
方法:3技术效果:阶段2。
BACKGROUND: Cardiovascular magnetic resonance (cardiac MR) reference ranges in Chinese children are lacking.
OBJECTIVE: To establish age- and sex-specific reference ranges for cardiac MR parameters in a cohort of healthy Chinese children.
METHODS: Retrospective.
METHODS: One hundred ninety-six healthy children (mean age 9.5 ± 3.6 years, 111 boys).
UNASSIGNED: 1.5 T; balanced steady-state free precession.
RESULTS: Biventricular volume and ejection fractions (EF), left atrial (LA) volume, right atrial (RA) area, left ventricular (LV) mass and thickness, aortic root (AR), and main pulmonary artery (MPA) dimensions were measured. Parameters were compared between age groups and sex. The relationships between parameters and age, body mass index (BMI) and body surface area (BSA) were investigated.
METHODS: Independent-samples t tests; Pearson\'s correlation. A P value <0.05 was considered statistically significant.
RESULTS: Generally, boys exhibited greater absolute measurements of LV volume (end-diastolic: 94.4 ± 29.5 vs. 81.3 ± 31.0 mL), LA volume (end-diastolic: 42.6 ± 13.4 vs. 38.0 ± 13.3 mL), RA area (end-diastolic: 11.6 ± 2.5 vs. 10.8 ± 2.6 cm2), LV thickness (base: 4.4 ± 1.1 vs. 3.8 ± 0.9 mm), AR dimensions (annuls: 16.3 ± 2.7 vs. 15.0 ± 2.8 mm), and MPA dimensions (14.3 ± 2.3 vs. 13.1 ± 2.4 mm) than girls did. However, these differences were not observed when the measurements were normalized to BSA (LV volume: 75.3 ± 11.7 vs. 71.9 ± 12.3 mL/m2, P = 0.052; LA volume: 34.8 ± 8.9 vs. 34.5 ± 7.6 mL/m2, P = 0.783; RA area: 9.7 ± 2.3 vs. 10.2 ± 2.3 cm2/m2, P = 0.107; LV thickness: 3.6 ± 0.7 vs. 3.6 ± 0.9 mm/m2, P = 0.990; AR: 13.6 ± 2.7 vs. 14.3 ± 3.4 mm/m2, P = 0.108; MPA: 11.9 ± 2.3 vs. 12.4 ± 2.4 mm/m2, P = 0.118). Boys had greater RV volume (end-diastolic: 98.7 ± 33.5 vs. 82.7 ± 33.1 mL) and LV mass (52.6 ± 20.2 vs. 41.4 ± 16.0 g) compared to girls, irrespective of whether the values were indexed or not for BSA. Additionally, there were significant associations between age, BMI, and BSA with biventricular volume, LA volume, RA area, LV mass and thickness, AR and MPA dimensions in both boys and girls.
CONCLUSIONS: This study suggests reference ranges at 1.5 T for Chinese children.
METHODS: 3 TECHNICAL EFFICACY: Stage 2.