癌症,糖尿病,创伤是影响全球数百万人的重大健康挑战。癌症产生于正常细胞转化为肿瘤细胞,导致不受控制的生长和潜力扩散到身体的其他部位。糖尿病是一种以血糖水平升高为特征的慢性代谢紊乱,各种伤害和疾病都可能造成伤口。在这项研究中,我们研究了芙蓉的抗癌治疗潜力,抗糖尿病药,和体外伤口愈合活性。使用MTT(3-[4,5-二甲基噻唑-2-基]-2,5二苯基四唑溴化物)测定法评估了罗莎中华乙醇提取物的抗癌活性,显示细胞增殖和生长的浓度依赖性降低。提取物显示出有希望的抗癌潜力,这可以帮助控制癌症进展。对于抗糖尿病活性,我们使用比色法评估了α-淀粉酶的抑制作用。提取物表现出显著的α-淀粉酶抑制活性,与标准二甲双胍相当。这表明其降低糖尿病患者餐后血糖峰值的潜力。在体外伤口愈合活动中,进行划痕试验以测量细胞迁移和生长.结果表明,与对照组相似,红景天提取物促进伤口闭合。提取物的伤口愈合特性表明其在处理各种类型的伤口中的潜在用途。植物化学分析证实了红景天的乙醇和水提取物中存在关键的生物活性化合物。支持观察到的治疗效果。总之,H.rosa-sinensis有望成为癌症新型治疗剂的潜在来源,糖尿病,和伤口管理。这项研究的结果为植物的药理活性提供了有价值的见解,并可能为开发新的草药治疗方法铺平道路。
Cancer, diabetes, and wounds are critical health challenges affecting millions of people worldwide. Cancer arises from the transformation of normal cells into tumor cells, leading to uncontrolled growth and potential spread to other parts of the body. Diabetes is a chronic metabolic disorder characterized by elevated blood sugar levels, and wounds can result from various injuries and diseases. In this study, we investigated the therapeutic potential of Hibiscus rosa-sinensis for its anticancer, antidiabetic, and in vitro wound healing activities. The anticancer activity of the ethanolic extract of H. rosa-sinensis was evaluated using the MTT (3- [4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide) assay, which showed a concentration-dependent decrease in cell proliferation and growth. The extract exhibited promising anticancer potential, which could help control cancer progression. For the antidiabetic activity, we assessed α-amylase inhibition using a colorimetric method. The extract demonstrated substantial α-amylase inhibitory activity, comparable with the standard metformin. This indicates its potential in reducing postprandial blood sugar spikes in diabetic patients. In the in vitro wound healing activity, a scratch assay was performed to measure cell migration and growth. The results showed that H. rosa-sinensis extract promoted wound closure similar to the control. The extract\'s wound healing properties suggest its potential use in managing various types of wounds. Phytochemical analysis confirmed the presence of key bioactive compounds in both ethanolic and aqueous extracts of H. rosa-sinensis, supporting the observed therapeutic effects. In conclusion, H. rosa-sinensis holds promise as a potential source of novel therapeutic agent for cancer, diabetes, and wound management. The results from this study provide valuable insights into the plant\'s pharmacological activities and may pave the way for the development of new herbal-based treatments for these conditions.