lens subluxation

晶状体半脱位
  • 文章类型: Journal Article
    本研究旨在分析韩国白内障手术后人工晶状体(IOL)脱位的发生率和特征。
    我们回顾性分析了2002年至2021年之间诊断的白内障手术后IOL脱位的发生率。从韩国国家健康保险系统(KNHIS)数据库和韩国疾病标准分类-7代码中提取所有由于IOL脱位而接受二次IOL或IOL交换手术的假晶状体患者的数据。计算每1,000,000人年的发病率和相应的95%置信区间(CI)。
    在2002年至2021年之间,4,848,125例假晶状体患者中有39,965例(0.82%)被诊断为IOL脱位并接受手术治疗。人工晶状体患者需要手术治疗的人工晶状体脱位发生率为28,900/1,000,000人年(95%CI:28,431-29,369),包括男性57,800例,女性患者10,800例(95%CI:男性:56,730-58,87095%CI:女性患者:10523-11077),平均男女比例为5.35。发病率在40岁以下的年轻年龄组达到峰值,显示每100万人年107,000(95%CI:102,900-111,100),需要手术治疗的人工晶状体脱位平均年龄为68.1±10.7岁。由于人工晶状体脱位,从白内障手术到二次人工晶状体手术的平均时间为4.1±4.7年(中位数,2.2年),在所有年龄段的白内障手术后10年,由于人工晶状体脱位而导致的二次IOL手术数量迅速发生。
    需要手术的人工晶状体脱位在年轻和男性患者中的发生率较高。我们的发现有望为白内障手术后IOL脱位风险增加的韩国人群制定未来的医疗保健政策。
    UNASSIGNED: This study aimed to analyze the incidence and characteristics of intraocular lens (IOL) dislocation after cataract surgery in South Korea.
    UNASSIGNED: We retrospectively analyzed the incidence of IOL dislocation after cataract surgery in patients diagnosed between 2002 and 2021. Data of all pseudophakic patients who underwent secondary IOL or IOL exchange surgeries due to IOL dislocation were extracted from the Korean National Health Insurance System (KNHIS) database and the Korean Standard Classification of Diseases-7 codes. The incidence per 1,000,000 person-years and corresponding 95% confidence intervals (CIs) were calculated.
    UNASSIGNED: Between 2002 and 2021, 39,965 (0.82 %) of the 4,848,125 pseudophakic patients were diagnosed with IOL dislocation and surgically treated. The incidence of IOL dislocation requiring surgery in pseudophakic patients was 28,900/1,000,000 person-years (95% CI: 28,431-29,369), comprising 57,800 cases in male and 10,800 in female patients (95% CI: male: 56,730-58,870 vs. 95% CI: female patients: 10,523-11,077), and mean male-to-female ratio was 5.35. The incidence rate peaked in younger age group below 40 years, showing 107,000 per 1,000,000 person-years (95% CI: 102,900-111,100), and the average age of IOL dislocation requiring surgery was 68.1 ± 10.7 years. The average time lapse from cataract surgery to secondary IOL surgery due to IOL dislocation was 4.1±4.7 years (median, 2.2 years), and the number of secondary IOL surgery due to dislocation of artificial lens rapidly occurred 10 years after cataract surgery among all age groups.
    UNASSIGNED: The incidence of IOL dislocation requiring surgery was higher in younger and male patients. Our findings could be expected to aid establishing future healthcare policies for South Korean populations with an increased risk of IOL dislocation after cataract surgery.
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  • 文章类型: Case Reports
    目的:描述一例双侧鼻上晶状体半脱位的马凡氏综合征患者。方法:以一名男性患者为例,18岁,自蹒跚学步以来,他抱怨双眼视力受损(BE),被介绍了。在检查病人时,揭示了暗示马凡氏综合征的特征,以及双侧人工晶状体半脱位。结果:患者折返,建议戴眼镜,这改善了他的视力。病人被转诊到心脏病学,骨科,和牙科部门的多学科方法,以防止并发症和进一步管理。讨论:晶状体半脱位通常是马凡氏综合征的主要临床表现。它可以从无症状的变化,只有在瞳孔扩张后才能看到,严重的半脱位,其中晶状体在瞳孔轴上的赤道导致复视或视力下降。结论:该病例强调了考虑马凡氏综合征罕见特征的重要性。
    Aim: To describe the case of a patient with Marfan syndrome who had bilateral superonasal lens subluxation. Method: The case of a male patient, aged 18, who complained of having impaired vision in both eyes (BE) since he was a toddler, was presented. On examination of the patient, features suggestive of Marfan syndrome were revealed, as well as bilateral intraocular lens subluxation. Results: The patient was refracted and glasses were recommended, which improved his vision. The patient was referred to the cardiology, orthopedic, and dental departments for a multidisciplinary approach to prevent complications and further management. Discussion: Lens subluxation is frequently presented as a primary clinical manifestation of Marfan syndrome. It can vary from asymptomatic, which is seen only after pupillary dilation, to significant subluxation, in which the equator of the lens in the pupillary axis causes diplopia or decreased vision. Conclusion: This case underscored the importance of considering the rare feature of Marfan syndrome.
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  • 文章类型: Journal Article
    背景:许多眼部或全身状况可导致小带减弱,导致晶状体半脱位或完全脱位进入前房或玻璃体腔。
    目的:评估晶状体半脱位和脱位的手术效果。
    方法:回顾性图表回顾了2019年1月至2019年12月在一年内接受手术的所有晶状体半脱位和脱位病例。人口概况,系统性合并症,初始和最终最佳矫正视力(BCVA),记录手术过程以及所有术中和术后并发症。
    结果:纳入60例患者的62只眼,平均年龄为50.18±15.18岁(18至87岁),模态表现持续时间为一周。其中,创伤是最常见的病因。55只眼睛出现半脱位,7只眼睛出现脱位。41例进行了白内障囊内摘除术(ICCE),21例进行了白内障囊外摘除术(ECCE);手术干预引起了视力的统计学显着提高(p<0.05)。假晶状体患者的BCVA在统计学上更好。术中最常见的并发症是玻璃体丢失,术后是严重的角膜水肿。
    结论:由于不同病因导致晶状体半脱位和脱位的患者摘除白内障可提高患者的视力。在无法执行ECCE的情况下,ICCE还导致相当的视觉改善。
    BACKGROUND: Many ocular or systemic conditions can cause weakening of the zonules, leading to subluxation or complete dislocation of lens into the anterior chamber or vitreous cavity.
    OBJECTIVE: To evaluate the outcome of surgery in cases with subluxated and dislocated lens.
    METHODS: Retrospective chart review of all cases with subluxated and dislocated lens who underwent surgery in a one-year period from 2019 January to 2019 December was conducted. Demographic profile, systemic comorbidities, initial and final best corrected visual acuity (BCVA), surgical procedure were recorded along with all the intraoperative and post-operative complications.
    RESULTS: A total of 62 eyes of 60 patients with mean age of 50.18 ± 15.18 years (18 to 87 years) were included with the modal duration of presentation of one week. Among these, trauma was found to be the most common etiology. Subluxation was present in 55 eyes and seven eyes had dislocation. Intracapsular Cataract Extraction (ICCE) was performed in 41 while 21 underwent Extracapsular Cataract Extraction (ECCE); and surgical intervention elicited a statistically significant (p < 0.05) improvement in the visual acuity. The BCVA was statistically better among the pseudophakic patient. Most common complication encountered intraoperatively was vitreous loss and post operatively was significant corneal edema.
    CONCLUSIONS: Cataract extraction in cases with subluxated and dislocated lens due to different etiology results in the improvement in the visual acuity of the patient. In cases where ECCE cannot be performed, ICCE also results in comparable visual improvement.
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  • 文章类型: English Abstract
    Congenital subluxation of the lens as a complication of Marfan syndrome, Weill-Marchesani syndrome, microspherophakia, etc. leads to the development of amblyopia and requires timely surgical treatment with removal of the subluxated lens and implantation of an artificial intraocular lens (IOL). IOL implantation in children with pathology of the ligamentous apparatus of the lens remains an urgent problem of ophthalmic surgery due to the lack of a consensus regarding the IOL fixation method among practitioners.
    OBJECTIVE: This study evaluated the effectiveness and safety of IOL implantation with transscleral fixation using the knotless Z-suture technique in pediatric patients with congenital lens subluxation.
    METHODS: The study included 24 children (36 eyes) with grade III congenital subluxation of the lens who underwent phacoaspiration of the subluxated lens with IOL implantation with transscleral fixation using the knotless Z-suture performed in the Kazakh Research Institute of Eye Diseases in Almaty in the period from 2017 to 2021. The average observation period was 31.7±11.3 months (2.0 to 4.5 years). The stability of the IOL position, the state of the intrascleral sutures, visual acuity after surgery, the presence and severity of complications in the long-term period were evaluated.
    RESULTS: All patients (100%) had a significant improvement in visual acuity after surgery. No intraoperative complications were registered in any of the cases. Postoperative complications were noted in 8.3% of cases (n=3). The final functional outcome of surgical treatment depended on the presence of concomitant pathology, the main cause of low vision was the development of refractive amblyopia due to refractive errors.
    CONCLUSIONS: The presented technique of transscleral fixation of IOL has proven to be reliable, which is especially important for pediatric patients considering their high physical activity and expected lifespan.
    Врожденная сублюксация хрусталика в детском возрасте при таких состояниях, как синдромы Марфана, Вейля—Марчезани, микросферофакия и др., приводит к развитию амблиопии и требует своевременного хирургического лечения с удалением сублюксированного хрусталика и имплантацией интраокулярной линзы (ИОЛ). Имплантация ИОЛ у детей с патологией связочного аппарата хрусталика остается актуальной проблемой офтальмохирургии ввиду отсутствия на сегодняшний день единого подхода к методу фиксации ИОЛ в мировой практике.
    UNASSIGNED: Оценка эффективности и безопасности имплантации ИОЛ с транссклеральной фиксацией с использованием метода безузлового Z-образного шва у пациентов детского возраста с врожденной сублюксацией хрусталика.
    UNASSIGNED: В исследование включено 24 ребенка (36 глаз) с врожденной сублюксацией хрусталика III степени, которым была проведена факоаспирация сублюксированного хрусталика с имплантацией ИОЛ с транссклеральной фиксацией безузловым Z-образным швом на базе КазНИИ глазных болезней (Алматы, Казахстан) в период с 2017 по 2021 г. Средний срок наблюдения составил 31,7±11,3 мес (от 2,0 до 4,5 года). Оценивали стабильность положения ИОЛ, состоятельность интрасклеральных швов, остроту зрения после операции, наличие и степень тяжести осложнений в отдаленном периоде.
    UNASSIGNED: У всех пациентов (100%) отмечалось достоверное улучшение остроты зрения после операции. Интраоперационных осложнений не было зарегистрировано ни в одном случае. Послеоперационные осложнения отмечены в 8,3% случаев (n=3). Окончательный функциональный результат хирургического лечения зависел от наличия сопутствующей патологии, основной причиной низкого зрения являлось развитие рефракционной амблиопии вследствие аномалий рефракции.
    UNASSIGNED: Представленная методика транссклеральной фиксации ИОЛ обеспечивает надежную фиксацию, что особенно актуально для пациентов детского возраста, учитывая их высокую физическую активность и предполагаемую продолжительность жизни.
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  • 文章类型: Case Reports
    一名29岁的男子被长期介绍,稳定,在远程彩弹伤的情况下单侧视力丧失。他的检查值得注意的是感觉外斜视以及后粘连的多个病灶,白色透镜状材料的片段和完全完整的囊内的透镜状细胞岛,以及受影响眼睛的严重小带性损害。大多数核晶状体材料不存在。患者被诊断为创伤后晶状体吸收,并接受了系统分析,囊切开术,切除残余透镜状材料,并放置了一个沟晶状体,手术后视力和眼线显着改善。我们的报告独特地强调了在存在完整的前囊和后囊的情况下,在吸收的晶状体中识别出Soemmering环,以及尽管治疗延迟了多年,但手术修复后成功的屈光和感觉运动结果。
    A 29-year-old man presented with longstanding, stable, unilateral vision loss in the setting of a remote paintball injury. His examination was notable for a sensory exotropia as well as multiple foci of posterior synechiae, segments of white lenticular material and islands of lenticular cells within a grossly intact capsule, and severe zonular compromise in the affected eye. The majority of the nuclear lens material was absent. The patient was diagnosed with post-traumatic lens absorption and underwent synechialysis, capsulotomy, excision of remnant lenticular material, and placement of a sulcus lens, with significant improvement in visual acuity and ocular alignment following surgery. Our report uniquely highlights identification of a Soemmering\'s ring in an absorbed lens in the presence of an intact anterior and posterior capsule as well as successful refractive and sensorimotor outcomes following surgical repair despite delay in treatment of many years.
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  • 文章类型: Journal Article
    目的:晶状体的半脱位(EctopiaLentis,EL)可导致明显的视力损害,并可作为诸如Marfan综合征之类的遗传性疾病的诊断标准。没有既定的标准来诊断和量化EL。我们前瞻性地研究了健康受试者的小带纤维插入与角膜缘(ZLD)之间的距离,作为评估晶状体位置的参数,量化EL并提供规范数据。
    方法:这种前瞻性,观察,横断面研究包括150名健康参与者的150只眼睛(平均年龄28岁,范围4-68)。用0.5%的托吡卡胺和2.5%的去氧肾上腺素滴眼液对学生进行扩张。ZLD在裂隙灯处的散瞳中测量为晶状体表面上带状纤维的最中心可见插入与角膜巩膜缘之间的距离。记录垂直瞳孔直径(PD)和屈光不正。如果带状纤维插入不可见,角膜缘和瞳孔边缘之间的距离记录为ZLD。
    结果:检查了145只右眼和5只左眼。93%的研究对象是白种人,7%是亚洲人。在可见小带纤维插入的眼睛中(n=76只眼睛),ZLD为1.30±0.28mm(平均值±SD,范围为0.7-2.1),PD为8.79±0.57mm(7.5-9.8)。在剩下的74只眼睛里,ZLD为1.38±0.28mm(0.7-2.1),PD为8.13±0.58mm(6.7~9.4)。对于所有的眼睛,ZLD为1.34±0.29mm(0.7-2.1),PD为8.47±0.66mm(6.7-9.8)。屈光不正和性别对ZLD无显著影响。较小的PD和年龄较大与较大的ZLD相关(分别为P<0.001和P=0.036)。
    结论:健康受试者的平均ZLD为1.34mm。年龄较大与ZLD较大相关。这些规范数据将有助于诊断和量化EL。
    OBJECTIVE: Subluxation of the crystalline lens (Ectopia Lentis, EL) can lead to significant visual impairment and serves as a diagnostic criterion for genetic disorders such as the Marfan syndrome. There is no established criterion to diagnose and quantify EL. We prospectively investigated the distance between the zonular fibre insertion and the limbus (ZLD) in healthy subjects as a parameter to assess the position of the lens, quantify EL and provide normative data.
    METHODS: This prospective, observational, cross-sectional study includes one-hundred-fifty eyes of 150 healthy participants (mean age 28 years, range 4-68). Pupils were dilated with tropicamide 0.5% and phenylephrine 2.5% eyedrops. ZLD was measured in mydriasis at the slit lamp as the distance between the most central visible insertions of the zonular fibres on the lens surface and the corneoscleral limbus. Vertical pupil diameter (PD) and refractive error were recorded. If zonular fibre insertions were not visible, the distance between limbus and the pupillary margin was recorded as ZLD.
    RESULTS: 145 right and 5 left eyes were examined. 93% of study subjects were Caucasian, 7% were Asian. In eyes with visible zonular fibre insertions (n = 76 eyes), ZLD was 1.30 ± 0.28 mm (mean ± SD, range 0.7-2.1) and PD was 8.79 ± 0.57 mm (7.5-9.8). In the remaining 74 eyes, ZLD was 1.38 ± 0.28 mm (0.7-2.1), and PD was 8.13 ± 0.58 mm (6.7-9.4). For all eyes, ZLD was 1.34 ± 0.29 mm (0.7-2.1), and PD was 8.47 ± 0.66 mm (6.7-9.8). Refractive error and sex did not significantly affect ZLD. Smaller PD and older age were associated with larger ZLD (P < 0.001 and P = 0.036, respectively).
    CONCLUSIONS: Average ZLD was 1.34 mm in eyes of healthy subjects. Older age correlated with larger ZLD. These normative data will aid in diagnosing and quantifying EL.
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  • 文章类型: Case Reports
    背景:Traboulsi综合征是一种散发性常染色体隐性遗传疾病。报道的病例很少,没有描述手术治疗。
    目的:本研究的目的是描述一例Traboulsi综合征伴cal间葡萄肿的手术治疗。
    结论:Traboulsi综合征[1-3]是一种自发性滤过泡。该病例是一名31岁的女士,患有平坦的前房和大的cal间葡萄肿,带有半脱位的透明晶状体。自由主义的peritomy已经完成。切割葡萄肿,并通过它输送移位的晶状体。用7-0vicryl连续缝合线将其封闭。在去除Descemet膜后使用交联的角膜。通过使用11和6mm的环钻对其进行修改以匹配角膜缘的新月形形状。产生了两个楔形缺损,并在它们之间切除了组织,然后缝合以增加圆弧半径。在角膜边缘处形成外围凸缘。在宿主角膜中形成口袋以容纳供体角膜凸缘。将供体角膜塞入并缝合移植物。巩膜用于预防性缝合另一侧,做一个360度的包围.患者术后有动态视力。以前没有描述过角膜作为生物包圈的用途。
    结论:使用交联角膜。在新月体角膜移植物中创建楔形缺损以增加圆弧半径。使用角膜作为包围。视频链接:https://youtu.be/T3b5rkvFmlc。
    BACKGROUND: Traboulsi syndrome is a sporadic autosomal recessive disorder. Very few cases reported and no surgical treatment has been described.
    OBJECTIVE: The purpose of the study was to describe the surgical treatment of a case of Traboulsi syndrome with intercalary staphyloma.
    CONCLUSIONS: Traboulsi syndrome[1-3] is a type of spontaneous filtering bleb. The case was of a 31-year-old lady with a flat anterior chamber and large intercalary staphyloma, with a subluxated clear lens. Liberal peritomy was done. The staphyloma was cut and the displaced lens was delivered through it. It was closed with 7-0 vicryl continuous suture. A cross-linked cornea was used after removing the Descemet membrane. It was modified to match the crescentic shape of the limbus by using 11 and 6 mm trephine. Two wedge-shaped defects were created and tissue was excised between them, which were then sutured to increase the arc radius. A peripheral flange at the corneal edge was created. A pocket was created in the host cornea to accommodate the donor corneal flange. The donor cornea was tucked in and the graft was sutured. The sclera was used to suture another side prophylactically, making a 360-degree encirclage. The patient got ambulatory vision postsurgery. The use of the cornea as biological encirclage has not been described previously.
    CONCLUSIONS: Using a cross-linked cornea. Creating wedge-shaped defects in crescentic corneal graft to increase arc radius. Use of cornea as encirclage.Link of video:https://youtu.be/T3b5rkvFmlc.
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  • 文章类型: Case Reports
    过成熟白内障是指白内障的晚期,没有进行及时的手术干预,导致进一步的进展,其特征是晶状体中的水含量降低,纤维的降解,以及其结构内的液化,这会导致体积减少,胶囊起皱,以及其表面的钙化或胆固醇结晶。此外,它可能导致前房加深。如果不及时治疗,这些并发症可能导致视力损害甚至失明。在过成熟的白内障中,晶状体核自发完全脱位进入前房的情况极为罕见。作者提出了一项案例研究,涉及一名74岁的女性患者,该患者被诊断为过度成熟的老年性白内障晶状体核完全脱位,没有任何明显的眼外伤或任何相关的医疗记录。在接受白内障摘除联合前路玻璃体切除术后,患者眼部不适得到缓解,并对手术结果表示满意;然而,她的视力没有显着改善。
    Overmature cataract refers to the advanced stage of cataract where timely surgical intervention is not performed, leading to further progression characterized by decreased water content in the lens, degradation of fibers, and liquefaction within its structure, which can cause a reduction in volume, wrinkling of the capsule, as well as calcification or cholesterol crystallization on its surface. In addition, it may result in deepening of the anterior chamber. If left promptly untreated, these complications may result in visual impairment or even blindness. The occurrence of spontaneous complete dislocation of the lens nucleus into the anterior chamber in overmature cataracts is extremely uncommon. The authors present a case study involving a 74-year-old female patient who was diagnosed with complete dislocation of the lens nucleus in an overmature senile cataract without any apparent ocular injury or any relevant medical records. After undergoing cataract removal combined with anterior vitrectomy, the patient experienced relief from eye discomfort and expressed satisfaction with the surgical outcome; however, her visual acuity did not show significant improvement.
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  • 文章类型: Case Reports
    背景:Parry-Romberg综合征(PRS)是一种病因不明的罕见进行性退行性疾病。本文报道1例罕见的PRS合并晶状体半脱位在复旦大学眼耳鼻喉科医院,上海。据我们所知,这是上海首例报告的PRS合并晶状体半脱位病例,通过超声乳化和CTR放置以及IOL植入手术治疗。
    方法:一名60岁女性因“右侧视觉模糊2年”被转诊,自12岁起患有病因不明的持续性右侧面瘫。她有右面部肌肉萎缩和瘫痪。眼部检查还显示右眼睑假性上下垂,眼球内陷,右眼存在年龄相关性白内障合并晶状体半脱位。患者被诊断为年龄相关性白内障和右眼晶状体半脱位以及进行性半面神经萎缩(Parry-Romberg综合征)。我们进行了联合超声乳化手术,全麻下患者行IOL和CTR植入及瞳孔成形术,术后UCVA为20/30,随访1年。
    结论:这里我们报道了一例罕见的PHA合并晶状体半脱位病例。经过适当的眼科手术,患者在右眼取得满意的视力结果。
    BACKGROUND: Parry-Romberg syndrome (PRS) is a rare progressive degenerative disorder of unknown etiology. Here we report a rare case of PRS combined with lens subluxation in Eye and ENT hospital of Fudan University, Shanghai. To our knowledge, it is the first reported case of PRS combined with lens subluxation that has been managed surgically with phacoemulsification and CTR placement and IOL implantation in Shanghai.
    METHODS: A 60-year-old woman was referred for \"right visual blur for 2 years\" and had persistent right facial paralysis of unknown etiology since the age 12. She had right facial muscle atrophy and paralysis. Eye examination also showed the right eyelid pseudoptosis, enophthalmos, age-related cataract combined with lens subluxation existed in the right eye. The patient was diagnosed as age-related cataract and lens subluxation in the right eye and progressive hemifacial atrophy (Parry-Romberg syndrome). We conducted a combined phacoemulsification, IOL and CTR implantation and pupilloplasty surgery for the patient under general anesthesia and the postoperative UCVA was 20/30 and remained for 1 year\'s follow up.
    CONCLUSIONS: Here we reported a rare case of PHA combined with lens subluxation in China. After appropriate eye surgery, the patient achieved satisfying vision result in the right eye.
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  • 文章类型: Case Reports
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