目的:调查FreeStyleLibre,间歇性扫描连续血糖监测(isCGM)系统,影响1型糖尿病成人患者治疗低血糖的信心.
方法:这种纵向,在一家机构进行的观察性研究包括121名1型糖尿病成人患者.参与者在使用isCGM之前使用常规的手指刺法进行血糖自测。在基线和开始isCGM后12个月,低血糖信心量表(HCS),糖尿病治疗满意度问卷(DTSQ),和HbA1c进行。12个月时,观察到使用isCGM趋势箭头进行血糖管理的个体百分比.主要终点是使用isCGM引起的低血糖信心变化。
结果:使用isCGM后,HCS评分从2.89(2.56,3.22)显着提高到3.00(2.20,3.33)(p<.001);中位数(25%,75%)。在基线时出现3级低血糖的参与者中,睡眠期间的低血糖信心(p<0.05),在社交场合(p<0.05),在避免严重低血糖相关问题方面(p<0.05)得到改善。尽管有低血糖风险,参与者可以通过使用isCGM继续日常活动(p<0.05),百分之六十九的人有效地利用了趋势箭头。
结论:使用isCGM改善了1型糖尿病成人的低血糖信心。数据分析表明,1型糖尿病患者可以更自由地生活,并使用isCGM更好地管理低血糖。
OBJECTIVE: To investigate whether the FreeStyle Libre, an intermittent scanning continuous glucose monitoring (
isCGM) system, influences confidence in managing hypoglycemia in adults with type 1 diabetes.
METHODS: This longitudinal, observational study conducted at one facility included 121 adults with type 1 diabetes. Participants used the conventional finger-prick method for self-testing glucose before using
isCGM. At baseline and 12 months after initiating isCGM, the Hypoglycemic Confidence Scale (HCS), Diabetes Treatment Satisfaction Questionnaire (DTSQ), and HbA1c were performed. At 12 months, the percentage of individuals utilizing isCGM trend arrows for glucose management was observed. The primary endpoint was hypoglycemic confidence change attributed to using
isCGM.
RESULTS: After using
isCGM, HCS scores improved significantly from 2.89 (2.56, 3.22) to 3.00 (2.20, 3.33) (p < 0.001); median (25%, 75%). Among participants with level 3 hypoglycemia at baseline, hypoglycemic confidence during sleep (p < 0.05), in social situations (p < 0.05), and in avoiding serious hypoglycemia-related problems (p < 0.05) were improved. Despite hypoglycemia risk, participants could continue daily activities by using
isCGM (p < 0.05), and sixty-nine percent utilized trend arrows effectively.
CONCLUSIONS: Using isCGM improved hypoglycemic confidence among adults with type 1 diabetes. Data analysis indicated that people with type 1 diabetes could live more freely and better manage hypoglycemia using isCGM.