{Reference Type}: Journal Article
{Title}: Predictors of the effectiveness of isCGM usage in adults with type 1 diabetes mellitus: post-hoc analysis of the ISCHIA study.
{Author}:  ;Murata T;Hirota Y;Hosoda K;Kato K;Kouyama K;Kouyama R;Kuroda A;Matoba Y;Matsuhisa M;Meguro S;Miura J;Nishimura K;Sakane N;Shimada A;Suzuki S;Tone A;Toyoda M;
{Journal}: Diabetol Int
{Volume}: 15
{Issue}: 3
{Year}: 2024 Jul
暂无{DOI}: 10.1007/s13340-023-00683-5
{Abstract}: <B>UNASSIGNED: </B>The Effect of Intermittent-Scanning Continuous Glucose Monitoring to Glycemic Control Including Hypoglycemia and Quality of Life of Patients with Type 1 Diabetes Mellitus (ISCHIA) study was a randomized, crossover trial that reported the decrease in time below range (TBR) by the use of intermittent-scanning continuous glucose monitoring (isCGM) combined with structured education in adults with type 1 diabetes (T1D) treated by multiple daily injections. The participants were instructed to perform frequent scanning of the isCGM sensor (10 times a day or more) and ingest sugar when impending hypoglycemia is suspected by tracking the sensor glucose levels and the trend arrow. We conducted post-hoc analysis to identify factors affecting difference in TBR (∆TBR), in time in range (∆TIR), and in time above range (∆TAR).<BR><B>UNASSIGNED: </B>Data from 93 participants who completed the ISCHIA study were used. Multiple regression analyses were performed to identify factors affecting CGM metrics.<BR><B>UNASSIGNED: </B>Pearson's correlation analysis showed the negative association between log-transformed scan frequency and with ∆TBR (r = - 0.255, P = 0.015), while there was no significant association of log-transformed scan frequency with ∆TIR (r = 0.172, P = 0.102) and ∆TAR (r = 0.032, P = 0.761), respectively. The log-transformed scan frequency was an independent predictor of ∆TBR (Beta = - 7.712, P = 0.022), but not of ∆TIR(Beta = 7.203, P = 0.091) and of ∆TAR (Beta = 0.514, P = 0.925).<BR><B>UNASSIGNED: </B>Our findings suggest that more frequent scanning of isCGM may be beneficial to reduce TBR in T1D adults.