UNASSIGNED: Web-based physical activity interventions often fail to reach the anticipated public health impact due to insufficient use by the intended audiences.
UNASSIGNED: The purpose of this study was to use a human-centered design process to optimize the user experience of the Interrupting Prolonged sitting with ACTivity (InPACT) at Home website to promote youth physical activity participation.
UNASSIGNED: Qualitative interviews were conducted to assess engagement and pain points with the InPACT at Home website. Interview data were used to create affinity maps to identify themes of user responses, conduct a heuristic evaluation according to Nielsen\'s usability heuristics framework, and complete a competitive analysis to identify the strengths and weaknesses of competitors who offered similar products.
UNASSIGNED: Key themes from end user interviews included liking the website design, finding the website difficult to navigate, and wanting additional features (eg, library of watched videos). The website usability issues identified were lack of labeling and categorization of exercise videos, hidden necessary actions and options hindering users from decision-making, error-prone conditions, and high cognitive load of the website. Competitive analysis results revealed that YouTube received the highest usability ratings followed by the Just Dance and Presidential Youth Fitness Program websites.
UNASSIGNED: Human-centered design approaches are useful for bringing end users and developers together to optimize user experience and impact public health. Future research is needed to examine the effectiveness of the InPACT at Home website redesign to attract new users and retain current users, with the end goal of increasing youth physical activity engagement.

The Hybridization problem asks to reconcile a set of conflicting phylogenetic trees into a single phylogenetic network with the smallest possible number of reticulation nodes. This problem is computationally hard and previous solutions are limited to small and/or severely restricted data sets, for example, a set of binary trees with the same taxon set or only two non-binary trees with non-equal taxon sets. Building on our previous work on binary trees, we present FHyNCH, the first algorithmic framework to heuristically solve the Hybridization problem for large sets of multifurcating trees whose sets of taxa may differ. Our heuristics combine the cherry-picking technique, recently proposed to solve the same problem for binary trees, with two carefully designed machine-learning models. We demonstrate that our methods are practical and produce qualitatively good solutions through experiments on both synthetic and real data sets.

I propose that moral distress may function as a moral heuristic, and one that misses its mark in signifying a fundamental source for nurses\' moral suffering. Epistemic injustice is an insidious workplace wrongdoing that is glossed over or avoided in explicit explanations for nurse moral suffering and is substituted by an emphasis on the nurse\'s own wrongdoing. I discuss reasons and evidence for considering moral distress as a moral heuristic that obfuscates the role of epistemic injustice as a fundamental constraint on nurses\' moral reasoning underlying moral suffering.

In this column, the author describes a heuristic framework for teaching-learning nursing made of the humanbecoming paradigm, living the art of humanbecoming, and the humanbecoming teaching-learning model. A story helps to clarify the heuristic framework.

This paper studies a variant of the Pollution Traveling Salesman Problem (PTSP) focused on fuel consumption and pollution emissions (PTSPC). The PTSPC generalizes the well-known Traveling Salesman Problem (TSP), classified as NP-Hard. In the PTSPC, a vehicle must deliver a load to each customer through a Hamiltonian cycle, minimizing an objective function that considers the speed of each edge, the mass of the truck, the mass of the load pending delivery, and the distance traveled. We have proposed a three-phase algorithm for the PTSPC. The first phase solves the Traveling Salesman Problem (TSP) exactly with a time limit and heuristically using a Nearest Neighborhood Search approach. This phase considers the constraints associated with the PTSPC by using commercial software. In the second phase, both the obtained solutions and their inverse sequences from the initial phase undergo enhancement utilizing metaheuristic algorithms tailored for the PTSPC. These algorithms include Variable Neighborhood Search (VNS), Tabu Search (TS), and Simulated Annealing (SA). Subsequently, for the third phase, the best solution identified in the second phase-determined by having the minimum value by the PTSPC objective function-is subjected to resolution by a mathematical model designed for the PTSPC, considering the heuristic emphasis of commercial software. The efficiency of the former algorithm has been validated through experimentation involving the adaptation of instances from the Pollution Routing Problem (PRP) to the PTSPC. This approach demonstrates the capacity to yield high-quality solutions within acceptable computing times.

In this research, a bio-inspired heuristic computing approach has been developed to solve the nonlinear behavior of the human liver, which is categorized into the liver and blood. The solutions of the human liver model are presented by using the stochastic computation procedure based on the artificial neural network (ANN) along with the optimization of genetic algorithm (GA) and interior-point (IP). A fitness function is designed through the differential form of the nonlinear human liver model and then optimized by using the hybrid competency of GAIP scheme. The correctness and exactness of the proposed approach are observed through the overlapping of the obtained (GAIP) and reference (Adams scheme) solutions, while the calculated absolute error values in good order enhance the worth of the proposed solver. The log-sigmoid transfer function together with ten numbers of neurons is executed to perform the solutions of the human liver nonlinear model. Furthermore, the statistical approaches have been applied in order to observe the reliability of the designed approach for solving the nonlinear human liver model.

Cognitive bias may lead to diagnostic error in the patient encounter. There are hundreds of different cognitive biases, but certain biases are more likely to affect patient diagnosis and management. As during morbidity and mortality rounds, retrospective evaluation of a given case, with comparison to an optimal diagnosis, can pinpoint errors in judgment and decision-making. The study of cognitive bias also illuminates how we might improve the diagnostic process. In Part 1 of this series, cognitive bias is defined and placed within the background of dual process theory, emotion, heuristics, and the more neutral term judgment and decision-making bias.

Cognitive bias may lead to medical error, and awareness of cognitive pitfalls is a potential first step to addressing the negative consequences of cognitive bias (see Part 1). For decision-making processes that occur under uncertainty, which encompass most physician decisions, a so-called \"adaptive toolbox\" is beneficial for good decisions. The adaptive toolbox is inclusive of broad strategies like cultural humility, emotional intelligence, and self-care that help combat implicit bias, negative consequences of affective bias, and optimize cognition. Additionally, the adaptive toolbox includes situational-specific tools such as heuristics, narratives, cognitive forcing functions, and fast and frugal trees. Such tools may mitigate against errors due to cultural, affective, and cognitive bias. Part 2 of this two-part series covers metacognition and cognitive bias in relation to broad and specific strategies aimed at better decision-making.

BACKGROUND: Large language models (LLMs) have shown remarkable capabilities in natural language processing (NLP), especially in domains where labeled data are scarce or expensive, such as the clinical domain. However, to unlock the clinical knowledge hidden in these LLMs, we need to design effective prompts that can guide them to perform specific clinical NLP tasks without any task-specific training data. This is known as in-context learning, which is an art and science that requires understanding the strengths and weaknesses of different LLMs and prompt engineering approaches.
OBJECTIVE: The objective of this study is to assess the effectiveness of various prompt engineering techniques, including 2 newly introduced types-heuristic and ensemble prompts, for zero-shot and few-shot clinical information extraction using pretrained language models.
METHODS: This comprehensive experimental study evaluated different prompt types (simple prefix, simple cloze, chain of thought, anticipatory, heuristic, and ensemble) across 5 clinical NLP tasks: clinical sense disambiguation, biomedical evidence extraction, coreference resolution, medication status extraction, and medication attribute extraction. The performance of these prompts was assessed using 3 state-of-the-art language models: GPT-3.5 (OpenAI), Gemini (Google), and LLaMA-2 (Meta). The study contrasted zero-shot with few-shot prompting and explored the effectiveness of ensemble approaches.
RESULTS: The study revealed that task-specific prompt tailoring is vital for the high performance of LLMs for zero-shot clinical NLP. In clinical sense disambiguation, GPT-3.5 achieved an accuracy of 0.96 with heuristic prompts and 0.94 in biomedical evidence extraction. Heuristic prompts, alongside chain of thought prompts, were highly effective across tasks. Few-shot prompting improved performance in complex scenarios, and ensemble approaches capitalized on multiple prompt strengths. GPT-3.5 consistently outperformed Gemini and LLaMA-2 across tasks and prompt types.
CONCLUSIONS: This study provides a rigorous evaluation of prompt engineering methodologies and introduces innovative techniques for clinical information extraction, demonstrating the potential of in-context learning in the clinical domain. These findings offer clear guidelines for future prompt-based clinical NLP research, facilitating engagement by non-NLP experts in clinical NLP advancements. To the best of our knowledge, this is one of the first works on the empirical evaluation of different prompt engineering approaches for clinical NLP in this era of generative artificial intelligence, and we hope that it will inspire and inform future research in this area.

Assembly line efficiency is one of the most important parameters that determine the overall efficiency of a manufacturing company. The production of a product under optimum conditions is ensured by a balanced assembly. With a balanced assembly line, machinery, material and labour costs are reduced. Within the scope of this research, real data about the daily production capacity and assembly line efficiency of a company producing Emergency Luminaire were taken, the same assembly line was balanced with 4 different Heuristic ALB methods and the results were compared. According to the results obtained, a high line efficiency of 93.955% was achieved using the Hoffman, Comsoal and Moodie&Young (M&Y) methods, and 84.414% was achieved with the Ranked Positional Weight (RPW) method. As a result of this, it was observed that the daily production capacity increased from 250 units to 375 units. As a result of the study, it was revealed that the efficiency of the existing assembly line and accordingly the daily production capacity increased. In addition, the study results of this assembly line were taught to an artificial neural network model for training purposes, and the work station results of the operations of a different assembly line were obtained with 99.940 accuracy. In this context, it has been revealed that the artificial neural networks method can be used in addition to the use of the heuristic method in the solution of ALB problems.