汉塔病毒科目前涵盖7属53种。多种汉坦病毒,如汉坦病毒,首尔病毒,多布拉瓦-贝尔格莱德病毒,Puumala病毒,安第斯山脉病毒,SinNombre病毒对人类有很高的致病性。在许多国家,它们会引起肾综合征出血热(HFRS)和汉坦病毒心肺综合征或汉坦病毒肺综合征(HCPS/HPS)。一些汉坦病毒感染野生或家畜而不会引起严重症状。啮齿动物,泼妇,蝙蝠是各种哺乳动物汉坦病毒的储库。近年来,汉坦病毒的研究取得了重大进展,包括基因组学,分类法,进化,复制,传输,致病性,control,和病人治疗。此外,新汉坦病毒感染蝙蝠,啮齿动物,泼妇,两栖动物,鱼已经被识别出来了.这篇综述汇编了这些进步,以帮助研究人员和公众更好地认识到这个具有全球公共卫生意义的人畜共患病毒家族。
Hantaviridae currently encompasses seven genera and 53 species. Multiple hantaviruses such as Hantaan virus, Seoul virus, Dobrava-Belgrade virus, Puumala virus, Andes virus, and Sin Nombre virus are highly pathogenic to humans. They cause hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome or hantavirus pulmonary syndrome (HCPS/HPS) in many countries. Some hantaviruses infect wild or domestic animals without causing severe symptoms. Rodents, shrews, and bats are reservoirs of various mammalian hantaviruses. Recent years have witnessed significant advancements in the study of hantaviruses including genomics, taxonomy, evolution, replication, transmission, pathogenicity, control, and patient treatment. Additionally, new hantaviruses infecting bats, rodents, shrews, amphibians, and fish have been identified. This review compiles these advancements to aid researchers and the public in better recognizing this zoonotic virus family with global public health significance.