关键词: Hantaviridae ICTV Report hantavirus orthohantavirus taxonomy

Mesh : Animals Humans RNA Viruses Negative-Sense RNA Viruses Virion / genetics Nucleoproteins Open Reading Frames Mammals

来  源:   DOI:10.1099/jgv.0.001975   PDF(Pubmed)

Abstract:
Hantaviridae is a family for negative-sense RNA viruses with genomes of about 10.5-14.6 kb. These viruses are maintained in and/or transmitted by fish, reptiles, and mammals. Several orthohantaviruses can infect humans, causing mild, severe, and sometimes-fatal diseases. Hantavirids produce enveloped virions containing three single-stranded RNA segments with open reading frames that encode a nucleoprotein (N), a glycoprotein precursor (GPC), and a large (L) protein containing an RNA-directed RNA polymerase (RdRP) domain. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family Hantaviridae, which is available at ictv.global/report/hantaviridae.
摘要:
Hantaviridae是负义RNA病毒的家族,基因组约为10.5-14.6kb。这些病毒保存在鱼类中和/或由鱼类传播,爬行动物,和哺乳动物。几种正强病毒可以感染人类,导致温和,严重,有时是致命的疾病。Hantavirids产生包膜病毒粒子,包含三个单链RNA片段,具有编码核蛋白(N)的开放阅读框,糖蛋白前体(GPC),和含有RNA指导的RNA聚合酶(RdRP)结构域的大(L)蛋白。这是国际病毒分类委员会(ICTV)关于汉塔病毒科的报告的摘要,可以在ictv上找到。全球/报告/hantaviridae.
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