free tissue flaps

自由组织皮瓣
  • 文章类型: Journal Article
    修复外科医生通常使用游离的前臂皮瓣进行鼻重建,当前额皮瓣不是一种选择时,但是这种皮瓣有缺点。本文介绍了一系列使用股前外侧(ALT)皮瓣进行重建的复杂缺损患者。严重烧伤和癌症切除可能导致多个解剖单元的丢失,包括整个鼻子和附近的结构。对于涉及相邻区域的复杂的总鼻缺损的患者,需要多种材料进行重建。在这一系列患者中,收集嵌合ALT瓣并使其变薄以重建三维鼻腔结构并覆盖相邻区域.软骨和异体材料被用作鼻框架,皮瓣折叠成粘膜衬里。结果很好,轮廓很好,随访期间无并发症及气道阻塞。通过减薄ALT皮瓣,这种皮瓣可以替代需要面部或三维鼻结构的复杂重建。
    Reconstructive surgeons often use a free radial forearm flap for nasal reconstruction when a forehead flap is not an option, but this flap has drawbacks. This article presents a series of patients with complex defects who underwent reconstruction with an anterolateral thigh (ALT) flap. Severe burns and cancer resection may lead to the loss of multiple anatomical units, including the entire nose and nearby structures. Multiple materials are required for reconstruction in those with complex total nasal defects involving adjacent areas. In this series of patients, a chimeric ALT flap was harvested and thinned to recreate the three-dimensional nasal structure and cover the adjacent area. Cartilage and alloplastic materials were used as the nasal framework, and the skin flap was folded for the mucosal lining. The results were good with an excellent contour, and no complications or airway obstruction were observed during follow-up. By thinning the ALT flap, this flap can be an alternative for complex reconstructions that require a facial or three-dimensional nasal structure.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    口腔颌面部肿瘤术后组织缺损的游离皮瓣重建是重建手术的重要组成部分。确定皮瓣坏死的危险因素对于改善手术效果和患者生活质量至关重要。对2020年1月至2023年12月接受游离皮瓣重建的患者进行了回顾性研究。如果患者有全面的医疗记录和至少六个月的随访,则将其包括在内。我们排除了有皮瓣坏死史的人,不受控制的系统性疾病,不坚持术后护理,或同时进行恶性肿瘤治疗。人口统计数据,合并症,襟翼特性,收集手术细节,采用单因素分析和logistic回归检验进行分析.单因素分析未发现皮瓣坏死与高脂血症、淋巴结转移,或皮瓣类型。然而,糖尿病,口腔感染,白蛋白水平低于35g/L与皮瓣坏死显著相关。多因素logistic回归分析显示糖尿病使皮瓣坏死的几率增加了约九倍,口腔感染使其增加了十倍以上。糖尿病,口腔感染,在口腔颌面外科术后游离皮瓣重建中,低白蛋白水平是皮瓣坏死的重要危险因素。及时识别和管理这些因素对于减轻皮瓣坏死的风险至关重要。
    Free flap reconstruction for postoperative tissue defects in oral and maxillofacial tumors is a critical component of reconstructive surgery. Identifying risk factors for flap necrosis is essential for improving surgical outcomes and patient quality of life. A retrospective study was conducted on patients who underwent free flap reconstruction between January 2020 and December 2023. Patients were included if they had comprehensive medical records and at least a six-month follow-up. We excluded those with a history of flap necrosis, uncontrolled systemic diseases, non-adherence to postoperative care, or concurrent malignancy treatments. Data on demographics, comorbidities, flap characteristics, and operative details were collected and analyzed using univariate analysis and logistic regression tests. Univariate analysis did not find a significant correlation between flap necrosis and factors such as hyperlipidemia, lymph node metastasis, or flap type. However, diabetes mellitus, oral infections, and albumin levels below 35 g/L were significantly associated with flap necrosis. Multivariate logistic regression showed diabetes mellitus increased the odds of flap necrosis by approximately ninefold, and oral infection increased it by over tenfold. Diabetes mellitus, oral infection, and low albumin levels are significant risk factors for flap necrosis in free flap reconstruction after oral and maxillofacial surgery. Prompt identification and management of these factors are crucial to mitigate the risk of flap necrosis.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    目的:研究下颌骨重建后软到硬组织的反应,并建立预测软组织运动的预测模型。
    方法:在这项回顾性研究中,纳入18例使用血管化皮瓣进行下颌骨重建的患者。考虑了用于表征组织运动的各种指标,以识别用于预测软组织运动的有效预测因子。构建并评估了用于预测的面部区域特定线性回归模型。
    结果:延伸区域硬组织运动的算术平均值与局灶性软组织运动的相关性最强,而区域内的算术平均值(Ram)是更有效的预测指标。使用Ram的线性回归模型,全局极值和它们之间的距离,因为预测因子在面部的下边缘表现最好,平均误差为1.51±1.38mm。牙槽突软组织运动与牙列的存在无关,只能通过它下面的软组织运动来预测。咬肌的面积与公羊有很强的相关性,但没有其他因素。
    结论:通过考虑硬组织和邻近的软组织运动,可以实现对面部下缘和肺泡突软组织运动的准确预测。没有确定咬肌区域的有效预测因子。
    结论:我们研究了面部区域硬组织运动与软组织反应之间的关系。通过建立预测术后软组织运动的预测模型,我们获得了对面部手术美学结果的见解。
    背景:本研究已在中国临床试验注册中心注册(注册号:ChiCTR2100054103)。
    OBJECTIVE: To investigate soft-to-hard tissue response following mandibular reconstruction and to develop a predictive model for projecting soft tissue movement.
    METHODS: In this retrospective study, 18 patients receiving mandibular reconstruction using a vascularized iliac flap were enrolled. Various indicators for characterizing the movement of tissues were considered to identify the effective predictors for projecting soft tissue movements. Face-region-specific linear regression models for prediction were constructed and evaluated.
    RESULTS: The arithmetic mean of hard tissue movement in an extended area had the strongest correlation with the movement of the focal soft tissue, while the arithmetic mean in a regional area (Ram) was a more effective predictor. The linear regression model using Ram, global extrema and distances between them as the predictors performed the best in the lower margin of the face, with an average error of 1.51 ± 1.38 mm. Soft tissue movement in the alveolar process was not correlated with the existence of dentition, only can be predicted by the soft tissue movement below it. The area of the masseter was strongly correlation with Ram, but no other factors.
    CONCLUSIONS: An accurate prediction of soft tissue movements in the lower margin and the alveolar process of the face can be achieved by considering hard tissue and adjacent soft tissue movements. No effective predictor in the masseter area was identified.
    CONCLUSIONS: We investigated the relationship between hard tissue movements and the soft tissue responses in the facial area. Through building predictive models for projecting postoperative soft tissue movements, we derive insights for the aesthetic outcome of face surgeries.
    BACKGROUND: This study was registered on the Chinese Clinical Trial Registry (registration number: ChiCTR2100054103).
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Case Reports
    背景:对于月骨坏死有几种手术选择,确认各种手术方法的有效性仍然具有挑战性。这里,我们介绍了一例使用游离的股骨内侧髁骨皮瓣修复的月骨IIIB期骨坏死。
    方法:一名43岁男建筑工人因右腕部疼痛入院,行动不便,10个月的活动会加重疼痛。根据右手腕的正骨图和磁共振成像,该患者被诊断为月骨IIIB期骨坏死。考虑到病人的病史,体检,辅助检查,和愿望,使用游离的股骨内侧髁骨皮瓣进行重建。皮瓣完全存活后,手术后一个月拆除了K线,手术后两个月移除外部支架,并启动功能性腕关节康复。经过六个月的随访,手腕肿胀和疼痛缓解,重建的月骨是可行的。此外,末次随访于术后第6个月;受影响的手握力与健康方(40kg)相比,由约70%(28kg)提高至80%(32kg);视觉模拟量表评分由术前6.5分降低至1分;MAYO评分由术前60分提高至85分.
    结论:该病例的成功加强了游离股骨内侧髁骨皮瓣作为IIIB期月骨坏死新的治疗选择的潜力,并进一步扩展了现有的治疗方案。使用自由的股骨内侧髁骨皮瓣重建月骨并恢复腕骨解剖可能。
    BACKGROUND: There are several surgical options for osteonecrosis of the lunate, and confirming the effectiveness of various surgical methods remains challenging. Here, we present a case of stage IIIB osteonecrosis of the lunate repaired with a free medial femoral condyle osteocutaneous flap.
    METHODS: A 43-year-old male construction worker was admitted to our hospital due to right wrist pain, impaired mobility, and pain aggravated by activity for 10 months. The patient was diagnosed with stage IIIB osteonecrosis of the lunate based on the orthopantomogram and magnetic resonance imaging of the right wrist. Considering the patient\'s medical history, physical examination, auxiliary examination, and wishes, reconstruction was performed using a free medial femoral condyle osteocutaneous flap. After the flap survived completely, the K-wires were removed one month after the operation, the external brace was removed two months after the operation, and functional wrist rehabilitation was initiated. After six months of follow-up, the wrist swelling and pain resolved, and the reconstructed lunate bone was viable. Additionally, the last follow-up was conducted in the sixth month after surgery; the affected hand grip strength improved from about 70% (28 kg) to 80% (32 kg) compared with the healthy side (40 kg); the visual analog scale score decreased from 6.5 points before the operation to 1 point; and the MAYO score increased from 60 points before the operation to 85 points.
    CONCLUSIONS: The success of this case reinforces the potential of the free medial femoral condyle osteocutaneous flap as a new treatment option for stage IIIB osteonecrosis of the lunate and further expands the existing treatment options. Using a free medial femoral condyle osteocutaneous flap to reconstruct the lunate and restore the carpal anatomy may.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:在微血管头颈部重建中,游离皮瓣组织的缺血在显微外科吻合术中是不可避免的,并可能影响微血管游离皮瓣的灌注,这是皮瓣生存能力的先决条件,也是皮瓣监测常用的参数。本研究的目的是研究缺血间隔数和缺血持续时间对皮瓣灌注的影响。
    方法:术中和术后皮瓣血流量,血红蛋白浓度,组织深度为2和8毫米的血红蛋白氧饱和度,用O2C组织氧分析系统测量,对2011年至2020年间接受微血管头颈部重建的330例患者进行了回顾性分析。在没有(对照患者)和第二次缺血间隔(早期或晚期)的患者之间比较了灌注值,并检查了缺血持续时间。
    结果:早期第二次缺血间隔患者的术中和术后组织深度为8mm的皮瓣血流量低于对照组患者[102.0任意单位(AU)vs122.0AU,P=.030;107.0AU与128.0AU,P=.023]。两种差异在多变量分析中仍然存在。对照组患者术中和术后8mm组织深度的皮瓣血流量与缺血持续时间呈弱负相关(r=-.145,P=.020;r=-.124,P=.048)。在多变量分析中,这两种关联都不存在。
    结论:在早期第二次缺血间隔后观察到的微血管皮瓣血流量减少可能反映了缺血相关的血管皮瓣组织损伤,应被视为皮瓣灌注监测中的混杂变量。
    BACKGROUND: In microvascular head and neck reconstruction, ischemia of the free flap tissue is inevitable during microsurgical anastomosis and may affect microvascular free flap perfusion, which is a prerequisite for flap viability and a parameter commonly used for flap monitoring. The aim of this study was to investigate the influence of the number of ischemia intervals and ischemia duration on flap perfusion.
    METHODS: Intraoperative and postoperative flap blood flow, hemoglobin concentration, and hemoglobin oxygen saturation at 2 and 8 mm tissue depths, as measured with the O2C tissue oxygen analysis system, were retrospectively analyzed for 330 patients who underwent microvascular head and neck reconstruction between 2011 and 2020. Perfusion values were compared between patients without (control patients) and with a second ischemia interval (early or late) and examined with regard to ischemia duration.
    RESULTS: Intraoperative and postoperative flap blood flow at 8 mm tissue depth were lower in patients with early second ischemia intervals than in control patients [102.0 arbitrary units (AU) vs 122.0 AU, P = .030; 107.0 AU vs 128.0 AU, P = .023]. Both differences persisted in multivariable analysis. Intraoperative and postoperative flap blood flow at 8 mm tissue depth correlated weakly negatively with ischemia duration in control patients (r = -.145, P = .020; r = -.124, P = .048). Both associations did not persist in multivariable analysis.
    CONCLUSIONS: The observed decrease in microvascular flap blood flow after early second ischemia intervals may reflect ischemia-related vascular flap tissue damage and should be considered as a confounding variable in flap perfusion monitoring.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:重症监护病房(ICU)收治的头颈部癌症患者与游离皮瓣重建相关的术后并发症的流行病学和危险因素尚不清楚。
    方法:我们对2015年9月至2023年4月北京同仁医院ICU收治的头颈部肿瘤游离皮瓣重建患者进行回顾性队列研究。采用单因素和多因素分析探讨ICU游离皮瓣重建术后并发症的危险因素。包括皮瓣坏死,出血,瘘管,和感染。
    结果:本研究共纳入239例患者,38例(15.9%)患者出现游离皮瓣重建相关的术后并发症。ICU住院时间中位数为1天(四分位距,1-2天)。多因素分析发现低BMI(P<0.001),术后CRP升高(P=0.005),低血红蛋白(P=0.012),液体摄入不足(P<0.05)是并发症发生的独立危险因素。
    结论:与游离皮瓣重建相关的术后并发症在ICU人群中很常见。仔细的液体管理和CRP和血红蛋白水平的监测可以减少并发症。
    BACKGROUND: The epidemiology and risk factors for postoperative complications related to free flap reconstruction in head and neck cancer patients admitted to the Intensive Care Unit (ICU) are unknown.
    METHODS: We performed a retrospective cohort study of patients with free flap reconstruction of head and neck cancer between September 2015 and April 2023 admitted to the ICU of Beijing Tongren Hospital. The univariate and multivariate analyses were used to explore the risk factors for postoperative complications related to free flap reconstruction admitted to ICU, including flap necrosis, bleeding, fistula, and infection.
    RESULTS: A total of 239 patients were included in this study, and 38 (15.9%) patients had postoperative complications related to free flap reconstruction. The median length of ICU stay was 1 day (interquartile range, 1-2 days). Multivariate analysis found that low BMI (P < 0.001), high postoperative CRP (P = 0.005), low hemoglobin (P = 0.012), and inadequate fluid intake (P < 0.05) were independent risk factors for complications.
    CONCLUSIONS: Postoperative complications related to free flap reconstruction were common in this ICU population. Careful fluid management and monitoring of CRP and hemoglobin levels may reduce complications.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    暂无摘要。
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    暂无摘要。
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    精心的术后皮瓣监测对于防止皮瓣失败和在游离皮瓣手术中达到最佳效果至关重要,体检仍然是标准。尽管体检的可靠性很高,过度使用临床医生时间的要求被认为是主要缺点。
    要开发使用人工智能(AI)的自动自由皮瓣监测系统,尽量减少人的参与,同时保持效率。
    在这项预后研究中,设计的系统包括安装在具有最佳襟翼可见性的位置的智能手机摄像头,以定期拍摄照片。自动程序识别襟翼区域,检查其外观是否有明显的异常,如果发现异常,通知医务人员。实施需要2种基于AI的模型:用于照片中自动皮瓣识别的分割模型和用于评估已识别皮瓣的灌注状态的分级模型。为了开发这个系统,用于监测的皮瓣照片收集自2020年3月1日至2023年8月31日接受游离皮瓣重建的患者.在开发了这两种模型之后,他们被整合来构建系统,2023年11月在临床上应用。
    执行开发的基于AI的自动襟翼监测系统。
    开发模型的准确性和系统临床应用的可行性。
    照片来自305名患者(中位年龄,62年[范围,8-86岁];男性为178[58.4%])。根据2068张照片,FS-net程序(定制模型)是为皮瓣分割开发的,证明平均(SD)骰子相似系数为0.970(0.001),具有5倍交叉验证。对于襟翼分级系统,使用了305名患者的11112张照片,包括10115张具有正常特征的照片和997张具有异常特征的照片。在5506张照片上测试,DenseNet121模型表现出最高的性能,接收器工作特征曲线下面积为0.960(95%CI,0.951-0.969)。检测静脉功能不全的灵敏度为97.5%,动脉功能不全的灵敏度为92.8%。当应用于10名患者时,该系统成功进行了143次自动监控会话,没有出现重大问题。
    这项研究的结果表明,一种新颖的自动化系统可以在最少使用临床医生时间的情况下实现有效的皮瓣监测。可以预期作为术后游离皮瓣监测的有效监测工具。需要进一步的研究来验证其可靠性。
    UNASSIGNED: Meticulous postoperative flap monitoring is essential for preventing flap failure and achieving optimal results in free flap operations, for which physical examination has remained the criterion standard. Despite the high reliability of physical examination, the requirement of excessive use of clinician time has been considered a main drawback.
    UNASSIGNED: To develop an automated free flap monitoring system using artificial intelligence (AI), minimizing human involvement while maintaining efficiency.
    UNASSIGNED: In this prognostic study, the designed system involves a smartphone camera installed in a location with optimal flap visibility to capture photographs at regular intervals. The automated program identifies the flap area, checks for notable abnormalities in its appearance, and notifies medical staff if abnormalities are detected. Implementation requires 2 AI-based models: a segmentation model for automatic flap recognition in photographs and a grading model for evaluating the perfusion status of the identified flap. To develop this system, flap photographs captured for monitoring were collected from patients who underwent free flap-based reconstruction from March 1, 2020, to August 31, 2023. After the 2 models were developed, they were integrated to construct the system, which was applied in a clinical setting in November 2023.
    UNASSIGNED: Conducting the developed automated AI-based flap monitoring system.
    UNASSIGNED: Accuracy of the developed models and feasibility of clinical application of the system.
    UNASSIGNED: Photographs were obtained from 305 patients (median age, 62 years [range, 8-86 years]; 178 [58.4%] were male). Based on 2068 photographs, the FS-net program (a customized model) was developed for flap segmentation, demonstrating a mean (SD) Dice similarity coefficient of 0.970 (0.001) with 5-fold cross-validation. For the flap grading system, 11 112 photographs from the 305 patients were used, encompassing 10 115 photographs with normal features and 997 with abnormal features. Tested on 5506 photographs, the DenseNet121 model demonstrated the highest performance with an area under the receiver operating characteristic curve of 0.960 (95% CI, 0.951-0.969). The sensitivity for detecting venous insufficiency was 97.5% and for arterial insufficiency was 92.8%. When applied to 10 patients, the system successfully conducted 143 automated monitoring sessions without significant issues.
    UNASSIGNED: The findings of this study suggest that a novel automated system may enable efficient flap monitoring with minimal use of clinician time. It may be anticipated to serve as an effective surveillance tool for postoperative free flap monitoring. Further studies are required to verify its reliability.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:广泛的胸壁重建的一种重建选择是游离的肌皮肤股外侧肌(VL)皮瓣,可以单独进行,也可以与股前外侧筋膜(cVLALT)和/或肌筋膜肌筋膜肌筋膜肌筋膜筋膜瓣(cVLTFL)联合进行。我们旨在直接比较这些重建方案的结果。
    方法:接受自由VL的肿瘤胸壁重建的患者,cVLALT,本回顾性研究包括2010年2月至2022年之间的cVLTFL皮瓣。患者人口统计学,手术特点,以及医疗和重建结果,进行了评估。肌皮VL,cVLALT,和cVLTFL皮瓣重建进行了比较。
    结果:共有41例患者接受了游离肌皮VL的胸壁重建(n=25;61%),cVLALT(n=14;34%),或cVLTFL在整个队列中发生了三个急性皮瓣血栓形成(3/41,7%),在抢救过程中,由于反复的静脉血栓形成,一个肌皮瓣VL失败。2例(5%;VL皮瓣:n=1;cVLALT皮瓣:n=1),一个VL皮瓣(1/25,4%)和三个cVLALT皮瓣的远端ALT部分(3/14,21%)的部分皮瓣坏死。在部分(p=.28)或全部皮瓣坏死率(p=.9)方面,分离的VL和连体VL皮瓣之间没有显着差异。
    结论:游离(连体)VL皮瓣为消除死腔提供了可靠的结果,可实现复杂胸壁缺损的持久重建。
    BACKGROUND: A reconstructive option for extensive chest wall reconstruction is the free myocutaneous vastus lateralis muscle (VL) flap which can be performed in isolation or in conjunction with a fasciocutaneus anterolateral thigh (cVLALT) and/or myofasciocutaneous tensor fascia lata flap (cVLTFL). We aimed to directly compare the outcomes of these reconstructive options.
    METHODS: Patients who underwent oncological chest wall reconstruction with a free VL, cVLALT, or cVLTFL flap between February 2010 and 2022 were included in this retrospective study. Patient demographics, surgical characteristics, as well as medical and reconstructive outcomes, were evaluated. The operative outcomes between myocutaneous VL, cVLALT, and cVLTFL flap reconstructions were compared.
    RESULTS: A total of 41 patients underwent chest wall reconstruction with a free myocutaneous VL (n = 25; 61%), cVLALT (n = 14; 34%), or cVLTFL Three acute flap thromboses occurred in the entire cohort (3/41, 7%), with one myocutaneous VL flap failing because of recurrent venous thrombosis during the salvage procedure. Total flap necrosis was seen in two cases (5%; VL flap: n = 1; cVLALT flap: n = 1), and partial flap necrosis in one VL flap (1/25, 4%) and in the distal ALT portion of three cVLALT flaps (3/14, 21%). No significant difference was seen between isolated VL and conjoined VL flaps regarding the partial (p = .28) or total flap necrosis rate (p = .9).
    CONCLUSIONS: The free (conjoined) VL flap provides reliable outcomes for obliterating dead space achieving durable reconstruction of complex chest wall defects.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

公众号