free tissue flaps

自由组织皮瓣
  • 文章类型: Case Reports
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  • 文章类型: Journal Article
    钛板和螺钉是用于乙状结肠后颅开颅手术如微血管减压术(MVD)后刚性骨瓣固定的常用材料。我们进行了这项研究,以评估MVD中无固定的游离骨瓣颅骨修补术的结果,并比较其与常规方法的术后并发症发生率。我们回顾性分析了2017年5月至2022年8月在我们机构接受MVD的所有患者。根据骨瓣是否固定分为两组。手术后6-28个月的随访期。通过乙状窦后入路接受MVD的189例患者中,79例(42%)在开颅手术后(<3cmx3cm)没有钛固定的情况下更换了骨瓣。与固定骨瓣组相比,游离骨瓣组手术时间较短(105.56±15.87minvs.113.72±17.80min,P=0.001),住院费用少(¥23059.66±4488.54vs.¥27714.82±2705.74,P<0.001),术后头痛和切口疼痛的比例较低(43.0%vs.60.9%,P=0.015)。游离骨瓣组发生切口脑脊液漏1例,固定骨瓣组发生切口感染1例。骨瓣位移无统计学差异,发现两组患者术后住院时间或并发症发生率。游离骨瓣组19例接受了长期CT随访,均证实颅骨愈合良好。本研究证明,无钛板固定的MVD游离骨瓣颅骨修补术可缩短手术时间,减少住院费用,且不增加并发症发生率。
    Titanium plates and screws are common material used for rigid bone flap fixation after retrosigmoid craniotomy such as microvascular decompression (MVD). We conducted this study to evaluate outcomes of the free bone flap cranioplasty without fixation in MVD and compared its postoperative complication rate with routine methods. We retrospectively reviewed all patients who underwent MVD at our institution from May 2017 to August 2022. Patients were divided into two groups according to whether the bone flap was fixed or not. Follow-ups periods spanned 6-28 months after the operation. Of 189 patients who underwent MVDs via retrosigmoid approach, 79 cases (42%) had their bone flaps replaced without titanium fixation after craniotomies (< 3 cm x 3 cm). Compared to fixed bone flap group, free bone flap group had shorter operative time (105.56 ± 15.87 min vs. 113.72 ± 17.80 min, P = 0.001), less in-patient costs (¥23059.66 ± 4488.54 vs. ¥27714.82 ± 2705.74, P < 0.001), and less proportion of postoperative headache and incisional pain (43.0% vs. 60.9%, P = 0.015). One case of incisional cerebrospinal fluid leak happened in free bone flap group while one case of incisional infection happened in fixed bone flap group. No statistical difference in bone flap displacement, duration of postoperative hospital stays or complication rate was found between the two groups. Nineteen patients in free bone flap group received long-term CT follow-up and all were proved to have good skull union. This study proves that free bone flap cranioplasty in MVD without titanium plate fixation can shorten the operation time and reduce hospitalization expenditure without increasing complication rates.
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  • 文章类型: English Abstract
    Objective:To investigate the therapeutic effect of free forearm flaps in repairing the postoperative defect of external nasal malignant tumor. Methods:Six patients with nasal malignant tumor were treated with radical operation of external nasal malignant tumor and simultaneous reconstruction of external nasal defects with free forearm flap. Preoperative Allen experiment, ultrasonic Doppler blood flow meter or CT angiography confirmed that the forearm blood vessels were in good condition. Results:The free forearm flaps were obtained from six patients, and completely survived. During the follow-up period of 6-12months, all patients had good external nasal morphology, good nasal function, no nasal obstruction and anterior nostril stenosis, no obvious complications in donor hand and no local cancer recurrence. Conclusion:The free forearm flap is a reliable method to reconstruction the postoperative defect of external nasal malignant tumor, with a high success rate and good recovery of morphology and function recovery.
    目的:探讨游离前臂皮瓣在外鼻恶性肿瘤术后缺损修复中的应用效果。 方法:对6例鼻部恶性肿瘤患者行外鼻恶性肿瘤根治性切除并同期行游离前臂皮瓣修复外鼻缺损,术前Allen实验及超声多普勒血流测量仪或CT血管造影确定前臂血管状态良好。 结果:6例患者游离前臂皮瓣制备及修复外鼻部缺损均成功,随访6~12个月,所有患者外鼻形态恢复良好,鼻腔功能良好,无鼻塞及前鼻孔狭窄出现,供区手部无明显并发症,局部无癌症复发。 结论:游离前臂皮瓣修复外鼻恶性肿瘤术后缺损成功率高,形态和功能恢复良好,是一种修复外鼻恶性肿瘤术后缺损的可靠方法。.
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  • 文章类型: Journal Article
    口腔颌面部肿瘤术后组织缺损的游离皮瓣重建是重建手术的重要组成部分。确定皮瓣坏死的危险因素对于改善手术效果和患者生活质量至关重要。对2020年1月至2023年12月接受游离皮瓣重建的患者进行了回顾性研究。如果患者有全面的医疗记录和至少六个月的随访,则将其包括在内。我们排除了有皮瓣坏死史的人,不受控制的系统性疾病,不坚持术后护理,或同时进行恶性肿瘤治疗。人口统计数据,合并症,襟翼特性,收集手术细节,采用单因素分析和logistic回归检验进行分析.单因素分析未发现皮瓣坏死与高脂血症、淋巴结转移,或皮瓣类型。然而,糖尿病,口腔感染,白蛋白水平低于35g/L与皮瓣坏死显著相关。多因素logistic回归分析显示糖尿病使皮瓣坏死的几率增加了约九倍,口腔感染使其增加了十倍以上。糖尿病,口腔感染,在口腔颌面外科术后游离皮瓣重建中,低白蛋白水平是皮瓣坏死的重要危险因素。及时识别和管理这些因素对于减轻皮瓣坏死的风险至关重要。
    Free flap reconstruction for postoperative tissue defects in oral and maxillofacial tumors is a critical component of reconstructive surgery. Identifying risk factors for flap necrosis is essential for improving surgical outcomes and patient quality of life. A retrospective study was conducted on patients who underwent free flap reconstruction between January 2020 and December 2023. Patients were included if they had comprehensive medical records and at least a six-month follow-up. We excluded those with a history of flap necrosis, uncontrolled systemic diseases, non-adherence to postoperative care, or concurrent malignancy treatments. Data on demographics, comorbidities, flap characteristics, and operative details were collected and analyzed using univariate analysis and logistic regression tests. Univariate analysis did not find a significant correlation between flap necrosis and factors such as hyperlipidemia, lymph node metastasis, or flap type. However, diabetes mellitus, oral infections, and albumin levels below 35 g/L were significantly associated with flap necrosis. Multivariate logistic regression showed diabetes mellitus increased the odds of flap necrosis by approximately ninefold, and oral infection increased it by over tenfold. Diabetes mellitus, oral infection, and low albumin levels are significant risk factors for flap necrosis in free flap reconstruction after oral and maxillofacial surgery. Prompt identification and management of these factors are crucial to mitigate the risk of flap necrosis.
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  • 文章类型: Journal Article
    目的:研究下颌骨重建后软到硬组织的反应,并建立预测软组织运动的预测模型。
    方法:在这项回顾性研究中,纳入18例使用血管化皮瓣进行下颌骨重建的患者。考虑了用于表征组织运动的各种指标,以识别用于预测软组织运动的有效预测因子。构建并评估了用于预测的面部区域特定线性回归模型。
    结果:延伸区域硬组织运动的算术平均值与局灶性软组织运动的相关性最强,而区域内的算术平均值(Ram)是更有效的预测指标。使用Ram的线性回归模型,全局极值和它们之间的距离,因为预测因子在面部的下边缘表现最好,平均误差为1.51±1.38mm。牙槽突软组织运动与牙列的存在无关,只能通过它下面的软组织运动来预测。咬肌的面积与公羊有很强的相关性,但没有其他因素。
    结论:通过考虑硬组织和邻近的软组织运动,可以实现对面部下缘和肺泡突软组织运动的准确预测。没有确定咬肌区域的有效预测因子。
    结论:我们研究了面部区域硬组织运动与软组织反应之间的关系。通过建立预测术后软组织运动的预测模型,我们获得了对面部手术美学结果的见解。
    背景:本研究已在中国临床试验注册中心注册(注册号:ChiCTR2100054103)。
    OBJECTIVE: To investigate soft-to-hard tissue response following mandibular reconstruction and to develop a predictive model for projecting soft tissue movement.
    METHODS: In this retrospective study, 18 patients receiving mandibular reconstruction using a vascularized iliac flap were enrolled. Various indicators for characterizing the movement of tissues were considered to identify the effective predictors for projecting soft tissue movements. Face-region-specific linear regression models for prediction were constructed and evaluated.
    RESULTS: The arithmetic mean of hard tissue movement in an extended area had the strongest correlation with the movement of the focal soft tissue, while the arithmetic mean in a regional area (Ram) was a more effective predictor. The linear regression model using Ram, global extrema and distances between them as the predictors performed the best in the lower margin of the face, with an average error of 1.51 ± 1.38 mm. Soft tissue movement in the alveolar process was not correlated with the existence of dentition, only can be predicted by the soft tissue movement below it. The area of the masseter was strongly correlation with Ram, but no other factors.
    CONCLUSIONS: An accurate prediction of soft tissue movements in the lower margin and the alveolar process of the face can be achieved by considering hard tissue and adjacent soft tissue movements. No effective predictor in the masseter area was identified.
    CONCLUSIONS: We investigated the relationship between hard tissue movements and the soft tissue responses in the facial area. Through building predictive models for projecting postoperative soft tissue movements, we derive insights for the aesthetic outcome of face surgeries.
    BACKGROUND: This study was registered on the Chinese Clinical Trial Registry (registration number: ChiCTR2100054103).
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  • 文章类型: Case Reports
    背景:对于月骨坏死有几种手术选择,确认各种手术方法的有效性仍然具有挑战性。这里,我们介绍了一例使用游离的股骨内侧髁骨皮瓣修复的月骨IIIB期骨坏死。
    方法:一名43岁男建筑工人因右腕部疼痛入院,行动不便,10个月的活动会加重疼痛。根据右手腕的正骨图和磁共振成像,该患者被诊断为月骨IIIB期骨坏死。考虑到病人的病史,体检,辅助检查,和愿望,使用游离的股骨内侧髁骨皮瓣进行重建。皮瓣完全存活后,手术后一个月拆除了K线,手术后两个月移除外部支架,并启动功能性腕关节康复。经过六个月的随访,手腕肿胀和疼痛缓解,重建的月骨是可行的。此外,末次随访于术后第6个月;受影响的手握力与健康方(40kg)相比,由约70%(28kg)提高至80%(32kg);视觉模拟量表评分由术前6.5分降低至1分;MAYO评分由术前60分提高至85分.
    结论:该病例的成功加强了游离股骨内侧髁骨皮瓣作为IIIB期月骨坏死新的治疗选择的潜力,并进一步扩展了现有的治疗方案。使用自由的股骨内侧髁骨皮瓣重建月骨并恢复腕骨解剖可能。
    BACKGROUND: There are several surgical options for osteonecrosis of the lunate, and confirming the effectiveness of various surgical methods remains challenging. Here, we present a case of stage IIIB osteonecrosis of the lunate repaired with a free medial femoral condyle osteocutaneous flap.
    METHODS: A 43-year-old male construction worker was admitted to our hospital due to right wrist pain, impaired mobility, and pain aggravated by activity for 10 months. The patient was diagnosed with stage IIIB osteonecrosis of the lunate based on the orthopantomogram and magnetic resonance imaging of the right wrist. Considering the patient\'s medical history, physical examination, auxiliary examination, and wishes, reconstruction was performed using a free medial femoral condyle osteocutaneous flap. After the flap survived completely, the K-wires were removed one month after the operation, the external brace was removed two months after the operation, and functional wrist rehabilitation was initiated. After six months of follow-up, the wrist swelling and pain resolved, and the reconstructed lunate bone was viable. Additionally, the last follow-up was conducted in the sixth month after surgery; the affected hand grip strength improved from about 70% (28 kg) to 80% (32 kg) compared with the healthy side (40 kg); the visual analog scale score decreased from 6.5 points before the operation to 1 point; and the MAYO score increased from 60 points before the operation to 85 points.
    CONCLUSIONS: The success of this case reinforces the potential of the free medial femoral condyle osteocutaneous flap as a new treatment option for stage IIIB osteonecrosis of the lunate and further expands the existing treatment options. Using a free medial femoral condyle osteocutaneous flap to reconstruct the lunate and restore the carpal anatomy may.
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  • 文章类型: Journal Article
    背景:重症监护病房(ICU)收治的头颈部癌症患者与游离皮瓣重建相关的术后并发症的流行病学和危险因素尚不清楚。
    方法:我们对2015年9月至2023年4月北京同仁医院ICU收治的头颈部肿瘤游离皮瓣重建患者进行回顾性队列研究。采用单因素和多因素分析探讨ICU游离皮瓣重建术后并发症的危险因素。包括皮瓣坏死,出血,瘘管,和感染。
    结果:本研究共纳入239例患者,38例(15.9%)患者出现游离皮瓣重建相关的术后并发症。ICU住院时间中位数为1天(四分位距,1-2天)。多因素分析发现低BMI(P<0.001),术后CRP升高(P=0.005),低血红蛋白(P=0.012),液体摄入不足(P<0.05)是并发症发生的独立危险因素。
    结论:与游离皮瓣重建相关的术后并发症在ICU人群中很常见。仔细的液体管理和CRP和血红蛋白水平的监测可以减少并发症。
    BACKGROUND: The epidemiology and risk factors for postoperative complications related to free flap reconstruction in head and neck cancer patients admitted to the Intensive Care Unit (ICU) are unknown.
    METHODS: We performed a retrospective cohort study of patients with free flap reconstruction of head and neck cancer between September 2015 and April 2023 admitted to the ICU of Beijing Tongren Hospital. The univariate and multivariate analyses were used to explore the risk factors for postoperative complications related to free flap reconstruction admitted to ICU, including flap necrosis, bleeding, fistula, and infection.
    RESULTS: A total of 239 patients were included in this study, and 38 (15.9%) patients had postoperative complications related to free flap reconstruction. The median length of ICU stay was 1 day (interquartile range, 1-2 days). Multivariate analysis found that low BMI (P < 0.001), high postoperative CRP (P = 0.005), low hemoglobin (P = 0.012), and inadequate fluid intake (P < 0.05) were independent risk factors for complications.
    CONCLUSIONS: Postoperative complications related to free flap reconstruction were common in this ICU population. Careful fluid management and monitoring of CRP and hemoglobin levels may reduce complications.
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  • 文章类型: Journal Article
    软组织肌上皮癌是罕见的,大多数是恶性的。最佳治疗方法是手术切除。足弓是一种复合结构,负责承重和压力分布,所以重建是一个巨大的挑战。我们报告了一例使用游离腓骨骨瓣和肌腱移植物重建中足的病例。我们回顾了文献,以比较足部重建中的各种选择,并整理出不同骨瓣的结果。游离腓骨骨皮瓣由于其足够的长度,是中足重建的首选,力量,灵活的皮肤桨,易于承受的截骨,同时收获肌腱移植物。
    UNASSIGNED: Myoepithelial carcinomas of soft tissue are rare, and most are malignant. The optimal treatment is surgical excision. The arches of the foot are a composite structure responsible for weight bearing and pressure distribution, so it is a vast challenge in reconstruction. We report a case of reconstruction of the midfoot with a free fibular bone flap and tendon graft. We review the literature to compare various options in foot reconstructions and sort out the outcomes of different bone flaps. The free fibula osteocutaneous flap is the superior choice for midfoot reconstruction owing to its sufficient length, strength, flexible skin paddles, easy-to-withstand osteotomy, and simultaneous tendon graft harvesting.
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  • 文章类型: Case Reports
    背景:由于挤压机制引起的高能创伤后腕部或前臂远端截肢与复杂的组织缺损有关,正在修理,重建具有挑战性。鉴于这种打捞的难度,不幸的是,患者的翻修截肢率高。然而,据报道,重建成功的患者的生活质量更高.在这里,我们描述了使用股前外侧皮瓣(ALT)从粉碎机制进行创伤性截肢后的功能性手抢救的血运重建和重建方法。
    方法:2016年10月至2023年10月对所有接受单阶段紧急清创的患者进行了回顾性研究,血运重建,在高能量挤压伤继发的腕部或前臂远端截肢后,使用ALT覆盖软组织。检查术前复杂肢体挽救评分的图表,术中细节,包括哪些结构受伤和重建方法,和术后数据,如随访时间,结果,和并发症。
    结果:11例患者符合纳入标准,平均年龄为35.5(21-49)岁。皮肤软组织缺损的平均大小为17.3×8cm(范围,长度:13-25厘米,宽度:6-13厘米),所有病例都对下面的骨骼有相关的损伤,神经,和血管。用于重建的ALT皮瓣的平均大小为19.2×9.8cm(范围,长度:14-27厘米,宽度:7-15厘米)。所有患者都有再植肢体的存活。一名患者出现部分皮瓣坏死,需要二次清创和皮肤移植。9例患者愈合,无需任何额外的清创程序。患者平均随访24.6(12-38)个月。所有患者均达到满意的功能恢复,符合陈氏标准的II至III级。
    结论:对于外伤性腕部挤压截肢伴周围软组织损伤的患者,彻底清创,血运重建,截肢的重建可以使用ALT在一个阶段进行。提出了来自两个机构的协议化方法,证明创伤肢体的生存率提高,并发症减少,患者的长期预后得到改善。
    BACKGROUND: Amputation of the wrist or distal forearm after high-energy trauma due to a crushing mechanism is associated with complex tissue defects, making repair, and reconstruction challenging. Given the difficulty of this type of salvage, patients unfortunately experience a high revision amputation rate. However, a higher quality of life has been reported in patients with successful reconstructions. Herein, we described a protocolized approach for revascularization and reconstruction for functional hand salvage after traumatic amputation from a crushing mechanism using an anterolateral thigh flap (ALT).
    METHODS: A retrospective review was performed between October 2016 and October 2023 for all patients who underwent single-stage emergent debridement, revascularization, and soft tissue coverage using the ALT after amputation at the level of the wrist or distal forearm secondary to high-energy crush injury. Charts were reviewed for the preoperative Mangled Extremity Salvage Score, intraoperative details including what structures were injured and the reconstructive method performed, and postoperative data such as follow-up duration, outcomes, and complications.
    RESULTS: Eleven patients met the inclusion criteria with an average age of 35.5 (21-49) years old. The average size of the skin soft tissue defects was 17.3 × 8 cm (range, length: 13-25 cm, width: 6-13 cm), and all cases had associated injury to the underlying bone, nerves, and blood vessels. The average size of the ALT flap used for reconstruction was 19.2 × 9.8 cm (range, length: 14-27 cm, width: 7-15 cm). All patients had survival of the replanted limb. One patient experienced partial flap necrosis that required secondary debridement and skin graft. Nine patients healed without requiring any additional debridement procedures. Patient follow-up averaged 24.6 (12-38) months. All patients achieved satisfactory functional recovery with Grade II to III of Chen\'s criteria.
    CONCLUSIONS: For patients with traumatic crush amputation to the wrist with surrounding soft tissue injury, thorough debridement, revascularization, and reconstruction of amputated limbs can be performed in a single stage using the ALT. A protocolized approach from two institutions is presented, demonstrating improved survival and reduced complications of the traumatized limb with improved long-term patient outcomes.
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