在意大利,鱼卵尚未被描述为过敏反应的诱因,特别是在儿科年龄;他们更频繁地参与在东方国家的过敏反应,比如日本。对于这份报告,我们报告了一例2岁男孩出现过敏反应,该男孩因疑似过敏反应入院至我院儿科急诊室.饭后15分钟,他提出了全身性荨麻疹,血管性水肿,喘息,打喷嚏,还有两次呕吐.这顿饭是烟熏鲑鱼,黄油,蛋黄酱,凤尾鱼,和鱼卵(鲑鱼和块状鱼卵)。类胰蛋白酶血清水平在急性期升高,24小时后正常。鲑鱼和其他鱼类的血清食物特异性IgE检测呈阴性,如皮肤点刺试验。血清食物特异性IgE显示患者对牛奶和鸡蛋敏感,但他没有食物过敏。在过敏反应之前和之后,他经常食用牛奶和鸡蛋,没有临床问题。逐刺测试显示鱼卵(鲑鱼和块状鱼卵)呈阳性。根据病人的病史,体内过敏测试结果,和类胰蛋白酶血清水平,诊断为鱼卵引起的过敏反应。总之,据我们所知,这是意大利报道的首例儿童鱼卵致过敏反应病例.
Fish roe are not yet described as triggers of allergic reactions in Italy, especially during the pediatric age; they are more frequently involved in anaphylaxis in Eastern countries, such as Japan. For this report, we reported a case of anaphylaxis in a 2-year-old boy admitted to our Hospital Pediatric Emergency Room with a suspected allergic reaction. 15 min after the meal, he presented generalized urticaria, angioedema, wheezing, sneezing, and two vomiting episodes. The meal was smoked salmon, butter, mayonnaise, anchovies, and fish roe (salmon and lumpfish roe). Tryptase serum levels presented as elevated in the acute phase and normal after 24 h. Serum food-specific IgE tested negative for salmon and other fish, such as skin prick tests. Serum food-specific IgE showed that the patient was sensitized to cow\'s milk and eggs, but he doesn\'t have a food allergy. He had regularly consumed milk and eggs before and after the allergic reaction without clinical problems. A prick-by-prick test resulted positive for fish roe (salmon and lumpfish roe). Based on patient\'s history, allergy test results in vivo, and tryptase serum levels, the diagnosis of anaphylaxis induced by fish roe was confirmed. In conclusion, to the best of our knowledge, this is the first pediatric case of fish roe-induced anaphylaxis reported in Italy.