■我们旨在通过确定出院时的喂养方式并在2-3天进行随访,来评估母体COVID-19感染和母婴分离对喂养方式的影响,14天,出院后1个月。
■这是一项在菲律宾总医院进行的前瞻性观察性队列研究,马尼拉的三级政府COVID-19转诊中心。在2021年7月至8月期间分娩的母亲,其COVID-19状态已知,在2-3天随访婴儿的喂养方式,14天,出院后1个月通过电话。对于COVID-19阳性母亲的婴儿,还确定了任何症状的存在(仅在14天时间点之前)以及对感染预防和控制措施的依从性.
■对于放电后的所有时间点,COVID-19阴性母亲所生婴儿的母乳喂养率较高。然而,差异无统计学意义。在108个婴儿中,72.90%的人在1月龄时仍然完全母乳喂养,配方饲喂4.67%,混合饲喂22.43%。对牛奶供应不足的认识是转向配方奶或混合喂养的最常见原因。我们发现,与入住NICU的人群相比,入住人群出院时的直接母乳喂养率明显更高。影响1月龄母乳喂养的危险因素是,由于NICU入院,母婴分离中存在COVID-19感染,COVID-19阳性母亲在1个月时仍母乳喂养的可能性较低66.02%(p=0.016,95%CI0.1411至0.8183),并且未发现分离是重要的危险因素。
喂养方式不仅会受到母亲感染COVID-19的影响,以及随之而来的困难,如住院时间长、身体和社会隔离,而且由于医院环境的限制,可能会对母乳喂养教育产生影响,支持,和母子结合的机会。
UNASSIGNED: We aimed to evaluate the impact of maternal COVID-19 infection and separation of the mother-baby dyad on feeding practices by determining modes of feeding upon discharge and following up at 2-3 days, 14 days, and 1 month post-discharge.
UNASSIGNED: This was a prospective observational cohort study conducted at the Philippine General Hospital, a tertiary government COVID-19 referral center in Manila. Mothers who delivered between the months of July and August 2021, and whose COVID-19 status was known were followed up on their baby\'s mode of feeding at 2-3 days, 14 days, and 1 month post-discharge via phone call. For babies of COVID-19 positive mothers, presence of any symptoms (up to the 14-day time point only) as well as adherence to infection prevention and control practices were also identified.
UNASSIGNED: For all time points post-discharge, breastfeeding rates were higher in babies born to COVID-19-negative mothers and in those who were roomed in. However, the differences were not statistically significant. Of the 108 infants, 72.90% remained exclusively breastfed by 1 month of age, with 4.67% formula-fed and 22.43% on mixed feeding. Perception of insufficient milk supply was the most common reason for shifting to formula or mixed feeding. We found a significantly higher direct breastfeeding rate upon discharge in the roomed-in population compared to those admitted to the NICU. Risk factors affecting breastfeeding at 1 month of age was the presence of COVID-19 infection in the mother and mother-baby separation due to NICU admissionCOVID-19-positive mothers were 66.02% less likely (p=0.016, 95% CI 0.1411 to 0.8183) to still be breastfeeding at 1 month, and separation was not found to be a significant risk factor.
UNASSIGNED: Feeding practices can be affected not only by COVID-19 infection in the mother and its attendant difficulties such as prolonged hospital stay and physical and social isolation, but also by limitations in the hospital environment that can have an impact on breastfeeding education, support, and opportunities for mother-child bonding.