esophagogastrostomy

食管胃吻合术
  • 文章类型: Journal Article
    一名74岁的男性患者在下床后被诊断为肋骨骨折5天后被转诊为败血症的迹象。在胸部X射线上可以看到新的低密度,实验室测试显示炎症参数升高。随后进行的胸部计算机断层扫描(CT)扫描显示第三胸椎爆裂骨折,创伤后同一水平食管破裂和纵隔炎。此外,存在明显的脊柱退行性变化(弥漫性特发性骨骼肥大)。患者接受了紧急开胸手术和食管切除术。食管胃吻合术的胃牵拉术被推迟3天。在重症监护病房(ICU)和12天的静脉注射抗生素后,患者被转移到普通病房,创伤后7周,患者无感染,无吞咽困难.受伤后41个月的最新随访,由于吻合口的收缩,已经进行了几次内窥镜扩张。与文献中以前的案例类似,食管损伤被诊断为延迟,患者已经出现严重并发症。高能量创伤后的年轻患者应该怀疑这种极其罕见的伤害,而且在低能创伤但已知脊柱退行性改变的老年患者中也是如此。
    A 74-year-old male patient was referred with signs of sepsis 5 days after having been diagnosed with a rib fracture following a fall out of bed. Novel hypodensities were visible on thoracic X‑rays and laboratory tests revealed elevated inflammatory parameters. Subsequently performed thoracic computed tomography (CT) scan showed burst fracture of the 3rd thoracic vertebra, posttraumatic esophageal rupture at the same level and mediastinitis. Furthermore, marked degenerative changes of the spinal column (diffuse idiopathic skeletal hyperostosis) were present. The patient underwent emergency thoracotomy and esophagectomy. Gastric pull-up with esophagogastrostomy was postponed for 3 days. After 14 days on the intensive care unit (ICU) and 12 days of i.v. antibiotics, the patient was transferred to the general ward and 7 weeks after trauma the patient was infection-free without difficulties in swallowing. Up to the latest follow-up 41 months following injury, several endoscopic dilations with a bougie due to constrictions at the anastomosis have been performed. Similar to previous cases in the literature, esophageal injury was diagnosed delayed, with the patient already having developed severe complications. This extremely seldom injury should be suspected in young patients following high-energy trauma, but also in older patients after low-energy trauma but known degenerative changes of the vertebral column.
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  • 文章类型: Journal Article
    目的:腹腔镜近端胃切除术(LPG)的最佳重建方法仍存在争议。本研究旨在比较短期结果,包括营养参数和骨骼肌的评估,在两种不同的方法之间,双道重建术(DTR)与食管胃吻合术(EG)。
    方法:回顾性分析了2018年至2021年期间接受LPG治疗胃肿瘤患者的数据。将患者分为两组:DTR(n=11)和EG(n=17)。自2020年以来,作者通过Yamashita(mSOFY)方法将改良的侧重叠与胃底折叠术作为EG技术。
    结果:与DTR相比,EG与较短的重建时间相关(p=0.003)。仅EG组发生≥3级并发症[n=4(23.5%)],EG组术后内镜检查结果异常的发生率在数值上较高(n=2vs.n=9;p=0.047)。在线图上几乎所有的数据点上,EG组出院后营养参数变化较大,骨骼肌指数也显示出显著的优越性(0.83vs.0.89;p=0.045)。
    结论:在液化石油气的重建方法中,EG在保持营养参数和骨骼肌质量方面优于DTR。然而,进一步研究,包括更大的队列和更长期的随访,是必要的,以验证这一发现。
    OBJECTIVE: The optimal reconstruction method for laparoscopic proximal gastrectomy (LPG) remains controversial. The present study aimed to compare short-term outcomes, including assessment of nutritional parameters and skeletal muscle, between two different methods, double-tract reconstruction (DTR) versus esophagogastrostomy (EG).
    METHODS: Data from patients who underwent LPG for gastric tumor(s) between 2018 and 2021, were retrospectively analyzed. Patients were divided into two group: DTR (n=11) and EG (n=17). Since 2020, the authors have applied the modified side overlap with fundoplication by Yamashita (mSOFY) method as the EG technique.
    RESULTS: Compared with DTR, EG was associated with a shorter reconstruction time (p=0.003). Complications of grade ≥3 occurred only in the EG group [n=4 (23.5%)] and the incidence of abnormal endoscopic findings after surgery was numerically higher in the EG group (n=2 vs. n=9; p=0.047). Across virtually all data points on the line graph, the EG group exhibited greater changes in post-discharge nutritional parameters, with Skeletal Muscle Index also demonstrating significant superiority (0.83 vs. 0.89; p=0.045).
    CONCLUSIONS: Among reconstruction methods for LPG, EG demonstrated superiority over DTR in preserving nutritional parameters and skeletal muscle mass. However, further research, including larger cohorts and longer-term follow-up, is necessary to validate this finding.
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  • 文章类型: Journal Article
    背景:随着上三胃早期胃癌的近端胃切除术(PG)的机会不断增加,PG的安全性和可行性近年来一直备受关注。这项研究旨在比较接受食管胃造口术(EG)的患者和接受PG术后双道重建(DTR)的患者的短期和长期结果。
    方法:我们回顾性回顾了2011年至2022年在我院接受EG治疗的34例患者和接受DTR治疗的39例患者的病历。我们比较了手术数据和术后并发症,包括术后1年内吻合口并发症,作为短期结局和营养状况的变化率,骨骼肌质量,和3年生存率作为长期结果。
    结果:尽管DTR组的手术时间明显长于EG组,两组患者术后并发症差异无统计学意义。关于内窥镜检查结果,EG组吻合口狭窄和反流性食管炎的发生率明显高于DTR组(26.5%vs0%,p<0.001;15.2%对0%,p=0.020)。在长期结果中,体重没有显著差异,BMI,实验室数据,两组间的骨骼肌质量指数为3年。两组的3年总生存率相似。
    结论:与EG相比,PG后DTR可以预防吻合口并发症的发生。这两种类型的重建的长期结果相似。
    BACKGROUND: As the opportunities for proximal gastrectomy (PG) for early gastric cancer in the upper third stomach have been increasing, the safety and feasibility of PG have been a great concern in recent years. This study aimed to compare the short-term and long-term outcomes between patients who underwent esophagogastrostomy (EG) and those who underwent double-tract reconstruction (DTR) after PG.
    METHODS: We retrospectively reviewed the medical records of 34 patients who underwent EG and 39 who underwent DTR at our hospital between 2011 and 2022. We compared the procedure data and postoperative complications including anastomotic complications within 1 year after surgery as short-term outcomes and the rates of change in nutritional status, skeletal muscle mass, and 3-year survival as long-term outcomes.
    RESULTS: Although operation time of the DTR group was significantly longer than that of the EG group, there were no significant differences in postoperative complications between 2 groups. Regarding the endoscopic findings, the incidence of anastomotic stenosis and reflux esophagitis was significantly higher in the EG group than in the DTR group (26.5% vs 0%, p < 0.001; 15.2% vs 0%, p = 0.020). In long-term outcomes, there were no significant differences in body weight, BMI, laboratory data, and skeletal muscle mass index between 2 groups for 3 years. The 3-year overall survival rates of 2 groups were similar.
    CONCLUSIONS: DTR after PG could prevent the occurrence of anastomotic complications in comparison to EG. The long-term outcomes were similar between these 2 types of reconstruction.
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  • 文章类型: Journal Article
    背景:近端胃切除术后没有最佳的重建方法。瓣膜性食管胃吻合术可减少术后反流性食管炎,但是它在技术上很复杂,运行时间很长。胃管吻合术技术简单,但反流性食管炎和吻合口狭窄的发生率较高。
    方法:我们设计了腹腔镜辅助近端胃切除术(LAPG)后改良的瓣膜性食管胃造口术,拱桥吻合术.在回顾了我们前瞻性维护的胃癌数据库后,从2021年11月至2023年4月接受LAPG的43例患者纳入本队列研究,其中25例患者接受了拱桥吻合术,18例患者接受了胃管吻合术。比较两组的近期疗效,评价拱桥吻合术的疗效。报告与STROCSS2021指南一致。
    结果:拱桥组的中位手术时间为180分钟,显著短于胃管组(p=0.003)。在拱桥组中,25例患者均未出现吻合口漏,而1例患者(4%)经历了需要内窥镜球囊扩张术的吻合口狭窄。拱桥组术后住院时间较短(9vs.11,p=0.034)。拱桥组的患者均未出现胃食管反流并使用质子泵抑制剂(PPI),而胃管组中有4例(22.2%)患者使用了PPI(p=0.025)。通过内窥镜检查,反流性食管炎(洛杉矶B级或更严重)的发生率在拱桥组中较低(0%vs.25.0%)。
    结论:拱桥吻合术是安全的,节省时间,可行的重建方法。它可以减少腹腔镜辅助近端胃切除术患者的术后反流和吻合口狭窄发生率。
    BACKGROUND: There is no optimal reconstruction method after proximal gastrectomy. The valvuloplastic esophagogastrostomy can reduce postoperative reflux esophagitis, but it is technically complex with a long operation time. The gastric tube anastomosis is technically simple, but the incidences of reflux esophagitis and anastomotic stricture are higher.
    METHODS: We have devised a modified valvuloplastic esophagogastrostomy after laparoscopy-assisted proximal gastrectomy (LAPG), the arch-bridge anastomosis. After reviewing our prospectively maintained gastric cancer database, 43 patients who underwent LAPG from November 2021 to April 2023 were included in this cohort study, with 25 patients received the arch-bridge anastomosis and 18 patients received gastric tube anastomosis. The short-term outcomes were compared between the two groups to evaluate the efficacy of the arch-bridge anastomosis. Reporting was consistent with the STROCSS 2021 guideline.
    RESULTS: The median operation time was 180 min in the arch-bridge group, significantly shorter than the gastric tube group (p = 0.003). In the arch-bridge group, none of the 25 patients experienced anastomotic leakage, while one patient (4%) experienced anastomotic stricture requiring endoscopic balloon dilation. The postoperative length of stay was shorter in the arch-bridge group (9 vs. 11, p = 0.034). None of the patients in the arch-bridge group experienced gastroesophageal reflux and used proton pump inhibitor (PPI), while four (22.2%) patients in the gastric tube group used PPI (p = 0.025). The incidence of reflux esophagitis (Los Angeles grade B or more severe) by endoscopy was lower in the arch-bridge group (0% vs. 25.0%).
    CONCLUSIONS: The arch-bridge anastomosis is a safe, time-saving, and feasible reconstruction method. It can reduce postoperative reflux and anastomotic stricture incidences in a selected cohort of patients undergoing laparoscopy-assisted proximal gastrectomy.
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  • 文章类型: Journal Article
    背景:对于近端胃切除术后的最佳重建技术尚无共识。这项研究的目的是回顾性比较食管胃造口术(EG)吻合术的手术结果,行腹腔镜近端胃切除术(LPG)的患者的胃管(GT)重建和双路(DT)重建,以阐明优越的重建方法。
    方法:本研究纳入了2017年1月至2022年1月在江苏省苏北人民医院接受LPG治疗的164例患者(EG:51例;GT:77例;DT:36例)。我们比较了临床和病理特征,手术特点,术后并发症,营养状况,以上三组的生活质量(QOL)。
    结果:DT组的平均手术时间长于其余两组(p=0.001)。关于术后并发症,发现三组之间的术后反流症状(p=0.042)和反流性食管炎(p=0.040)存在相当大的差异。关于营养状况,总蛋白质,术后12个月时,GT组的血红蛋白和白蛋白减少率显著高于其他两组.在PGSAS-45中,DT组的三个评估项目明显优于食管反流亚量表(p=0.047,Cohen\sd=0.44),对膳食的不满(p=0.009,科恩的d=0.58),和对日常生活分量表的不满(p=0.012,科恩的d=0.56)。
    结论:液化石油气后DT是一种有价值的重建技术,具有令人满意的手术效果,尤其是反流症状减少,改善术后营养状况和生活质量。
    BACKGROUND: There is no consensus on the optimal reconstruction technique after proximal gastrectomy. The purpose of this study was to retrospectively compare the surgical outcomes among esophagogastrostomy (EG) anastomosis, gastric tube (GT) reconstruction and double-tract (DT) reconstruction in patients who underwent laparoscopic proximal gastrectomy (LPG) to clarify the superior reconstruction method.
    METHODS: This study enrolled 164 patients who underwent LPG at the Northern Jiangsu People\'s Hospital in Jiangsu between January 2017 to January 2022 (EG: 51 patients; GT: 77 patients; DT: 36 patients). We compared the clinical and pathological characteristics, surgical features, postoperative complications, nutritional status, and quality of life (QOL) among the above three groups.
    RESULTS: Mean operative time was longer with the DT group than the remaining two groups (p = 0.001). With regard to postoperative complications, considerable differences in the postoperative reflux symptoms (p = 0.042) and reflux esophagitis (p = 0.040) among the three groups were found. For the nutritional status, total protein, hemoglobin and albumin reduction rates in the GT group were significantly higher than the other two groups at 12 months postoperatively. In the PGSAS-45, three assessment items were better in the DT group significantly compared with the esophageal reflux subscale (p = 0.047, Cohen\'s d = 0.44), dissatisfaction at the meal (p = 0.009, Cohen\'s d = 0.58), and dissatisfaction for daily life subscale (p = 0.012, Cohen\'s d = 0.56).
    CONCLUSIONS: DT after LPG is a valuable reconstruction technique with satisfactory surgical outcomes, especially regarding reduced reflux symptoms, improving the postoperative nutritional status and QOL.
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  • 文章类型: Journal Article
    背景:吻合口漏(AL)是食管癌患者食管次全切除术后最严重的术后并发症之一。本研究试图开发一种最佳评分系统,以对AL的风险进行分层。
    方法:本研究纳入了从2011年1月至2021年4月在名古屋大学医院接受食道癌次全食管切除术后颈部食管胃吻合术的171例患者。使用某些方式,通过放射学或内窥镜检查吻合口破裂的证据来定义AL。使用多变量分析中确定的因素建立了早期诊断AL的风险评分系统。计算每个病人的分数,根据AL的风险将患者分为三类:低,中等风险和高风险。评估了类别中AL的风险趋势。
    结果:29例患者(17%)发展为AL。多变量分析表明,引流液的总体特征(P<0.001;比值比(OR),10.2),放射性气泡征(P<0.001;OR,15.0)和术后第7天的引流淀粉酶水平≥280U/L(P<0.001;OR,9.0)与AL显著相关。根据以上三个风险因素的匹配数,将其分为三个风险组,低危组AL的发生率为6.1%(8/131),中危组的45.5%(15/33)和高风险组的85.7%(6/7)(曲线下面积,0.81;95%置信区间,0.72-0.90)。
    结论:目前的AL风险评分系统可能对食管次全切除术后的患者护理有用。
    BACKGROUND: Anastomotic leakage (AL) is one of the most critical postoperative complications after subtotal esophagectomy in patients with esophageal cancer. This study attempted to develop an optimal scoring system for stratifying the risk for AL.
    METHODS: The study included 171 patients who underwent subtotal esophagectomy for esophageal cancer followed by esophagogastrostomy in the cervical region from January 2011 to April 2021 at Nagoya University Hospital. AL was defined by radiologic or endoscopic evidence of anastomotic breakdown using some modalities. A risk scoring system for an early diagnosis of AL was established using factors determined in the multivariate analysis. A score was calculated for each patient, and the patients were classified into three categories according to the risk for AL: low-, intermediate- and high-risk. The trend of the risk for AL among the categories was evaluated.
    RESULTS: Twenty-nine patients (17%) developed AL. Multivariate analysis demonstrated that sinistrous gross features of drain fluid (P < 0.001; odds ratio (OR), 10.2), radiologic air bubble sign (P < 0.001; OR, 15.0) and the level of drain amylase ≥280 U/L on postoperative Day 7 (P < 0.001; OR, 9.0) were significantly associated with AL. According to the matching number of the above three risk factors and categorization into three risk groups, the incidence of AL was 6.1% (8/131) in the low-risk group, 45.5% (15/33) in the intermediate-risk group and 85.7% (6/7) in the high-risk group (area under curve, 0.81; 95% confidence interval, 0.72-0.90).
    CONCLUSIONS: The present AL-risk scoring system may be useful in postoperative patient care after subtotal esophagectomy.
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  • 文章类型: Review
    食管穿孔或破裂的治疗是复杂和有争议的,尤其是在先进的情况下。事实上,人们普遍认为,这种疾病必须根据位置单独治疗,破裂或穿孔的原因和临床特征。我们部门收治了一个非常罕见的病例,5天前,他被运行中的空气压缩机的高压气体炸伤,导致胸段食管长期纵向破裂。尽管患者同时患有脓胸和纵隔炎,他的情况很严重,脓胸的清创和脱屑仍在实施,随后在同一时期进行了左胸食管切除术和左颈入路食管胃吻合术。病人最终取得了良好的结果。
    Treatment of esophageal perforation or rupture is complicated and controversial, especially in advanced cases. In fact, it is generally accepted that this disease must be treated individually according to the location, causes and clinical features of rupture or perforation. A very rare case was admitted to our department, who was injured 5 days ago by high-pressure gas of a running air compressor and resulted in a long-term longitudinal rupture of the thoracic esophagus. Although the patient suffered from empyema and mediastinitis at the same time, and his condition was very serious, the debridement and desquamation of empyema were still implemented, followed by left thoracic esophagectomy and left neck approach esophagogastrostomy in the same period successfully. The patient got a good result finally.
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  • 文章类型: Journal Article
    本研究使用胃切除术后综合征评估量表(PGSAS)-45比较了近端胃切除术后食管胃吻合术(PGEG)和双道法(PGDT)的术后生活质量(QOL)。
    在接受PGSAS-45问卷的2364名患者中,300例PGEG和172例PGDT病例反应。主要结果测量(MOMs)包括七个涵盖症状的分量表(SS),膳食(数量和质量),工作能力,对日常生活的不满,8项简短形式健康调查(SF-8)的身体和心理组成部分摘要,和体重的变化,并对PGEG和PGDT进行了比较。
    总的来说,PGDT促进明显优于便秘SS评分(p<0.05),而PGEG倾向于促进更好的体重(BW)损失%(p<0.10)。根据残胃大小进行的分层分析显示,在残胃大小为1/2的患者中,PGDT的便秘和倾倒SS评分明显更好(p<0.05),并且工作条件更好(p<0.10)。即使在残胃大小为2/3的人群中,PGDT的腹泻SS评分也明显更好,对症状的不满程度较低,与PGEG相比,对日常生活SS评分的不满意度更好(p<0.05),并且倾向于便秘SS评分和对工作的不满意度更低(p<0.10)。
    比较PGEG和PGDT的QOL后,根据1/2和2/3的残胃大小进行的分层分析显示,对于几种MOM,PGDT相对优于PGEG。
    UNASSIGNED: The current study compared the postoperative quality of life (QOL) between the esophagogastrostomy method (PGEG) and double tract method (PGDT) after proximal gastrectomy using the Postgastretomy Syndrome Assessment Scale (PGSAS)-45.
    UNASSIGNED: Among the 2364 patients who received the PGSAS-45 questionnaire, 300 PGEG and 172 PGDT cases responded. The main outcomes measures (MOMs) consisted of seven subscales (SS) covering symptoms, meals (amount and quality), ability to work, dissatisfaction with daily life, physical and mental component summary of the 8-Item Short Form Health Survey (SF-8), and change in body weight, and were compared between PGEG and PGDT.
    UNASSIGNED: Overall, PGDT promoted significantly better constipation SS scores (p < 0.05), whereas PGEG tended to promote better body weight (BW) loss% (p < 0.10). A stratified analysis based on the remnant stomach size revealed that among those with a remnant stomach size of 1/2, PGDT had significantly better constipation and dumping SS scores (p < 0.05) and tended to have better working conditions (p < 0.10) compared to PGEG. Even among those with the remnant stomach size of 2/3, PGDT had significantly better diarrhea SS scores, lesser dissatisfaction with symptoms, and better dissatisfaction with daily life SS scores (p < 0.05) and tended to have better constipation SS scores and lesser dissatisfaction with work (p < 0.10) compared to PGEG.
    UNASSIGNED: After comparing the QOLs of PGEG and PGDT, the stratified analysis according to remnant stomach sizes of 1/2 and 2/3 revealed that PGDT was relatively superior to PGEG for several MOMs.
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  • 文章类型: Journal Article
    背景:近端胃切除术后没有标准的重建方法,其中胃食管反流和吻合口并发症备受关注。尽管已经设计了几种技术来克服这些术后并发症,如双道重建,山下双瓣技术和侧重叠胃底折叠术,他们都不被认为是一个完美的解决方案。在这里,我们设计了一种腹腔镜近端胃切除术(LPG)后食管胃吻合术的新方法,命名为右侧重叠和单瓣瓣膜成形术(ROSF)。
    方法:在2021年3月至2021年12月之间,有20名连续患者在胃肠外科接受了LPG-ROSF,苏州大学附属第二医院.记录手术效果及术后并发症。所有患者均随访至2022年12月。手术后1年进行内镜检查和胃肠道症状评估。营养相关参数,包括总体重,血红蛋白,淋巴细胞计数,血清总蛋白,术后1年评估血清白蛋白和血清前白蛋白,并与手术前进行比较。
    结果:平均手术时间和吻合时间分别为285.3±71.3和61.3±11.2分钟。所有患者均未出现术后早期胃肠道并发症。在一名患者(5%)中观察到有症状的反流,而在另一名患者(5%)中观察到反流性食管炎(洛杉矶A级)。4例患者(20%)有轻度吞咽困难(Visick评分=II),但均无吻合口狭窄。术后营养状况无明显变化。
    结论:ROSF可以安全地在LPG后进行,并且在预防反流和狭窄方面具有令人满意的结果,保持营养状况。该技术需要进一步验证。
    BACKGROUND: There is no standard reconstruction method following proximal gastrectomy, of which gastroesophageal reflux and anastomotic complications are of great concern. Though several techniques have been devised to overcome these postoperative complications, such as double tract reconstruction, double-flap technique and side overlap fundoplication by Yamashita, none of them is considered a perfect solution. Herein, we designed a novel method of esophagogastrostomy after laparoscopic proximal gastrectomy (LPG), named right-sided overlap and single-flap valvuloplasty (ROSF).
    METHODS: Between March 2021 and December 2021, 20 consecutive patients underwent LPG-ROSF at Department of Gastrointestinal Surgery, Second Affiliated Hospital of Soochow University. Surgical outcomes and postoperative complications were recorded. All patients were followed-up until December 2022. Endoscopy and assessment of gastrointestinal symptoms were performed 1 year after surgery. Nutrition-related parameters including total body weight, hemoglobin, lymphocyte count, serum total protein, serum albumin and serum prealbumin were evaluated 1 year after surgery and compared with those before surgery.
    RESULTS: The mean surgery time and anastomosis time was 285.3 ± 71.3 and 61.3 ± 11.2 min respectively. None of the patients had gastrointestinal early postoperative complications. Symptomatic reflux was observed in one patient (5%) while reflux esophagitis (Los Angeles Grade A) was observed in another patient (5%). Four patients (20%) had mild dysphagia (Visick score = II) but none of them had anastomotic stenosis. There were no significant changes in nutritional status postoperatively.
    CONCLUSIONS: ROSF can be safely performed after LPG and has satisfactory outcomes in preventing reflux and stenosis, and maintaining nutritional status. This technique requires further validation.
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  • 文章类型: Clinical Trial
    背景:近端胃癌的外科手术仍是一个备受争议的话题。全胃切除术(TG)被广泛接受为标准的根治性手术。然而,食管次全切除术,近端胃切除术(PG)甚至胃大部切除术,当胃的一小部分在技术上可以被保存时,是当前临床实践中的替代方案。
    方法:使用PGSASNEXT试验的队列,由1909名患者组成,对2018年7月至2019年12月期间发送到70个机构的调查问卷做出回应,胃切除术类型,重建方法,此外,还评估了残余胃的大小和PG的抗反流程序。
    结果:TG是最常见的程序(63.0%),其次是PG(33.4%)。无论食管肿瘤侵袭如何,TG后优先使用Roux-en-Y,而空肠袋在8.5%的腹部食管残端病例中被采用。食管胃造口术最常见于PG后,其次是双道法。前者优先用于较大的残余胃(≥3/4),在残胃2/3大小的情况下,与没有食道侵袭的肿瘤相比,肿瘤的使用频率略低。随着残胃大小的减小,双道法的应用逐渐增加。食管胃造口术后的抗反流程序差异显着。
    结论:在目前的日本近端胃癌临床实践中,TG是主流,PG仍然是一种替代方法。剩余的胃大小和食管残端位置似乎会影响PG后重建方法的选择。
    BACKGROUND: Surgical procedures for proximal gastric cancer remain a highly debated topic. Total gastrectomy (TG) is widely accepted as a standard radical surgery. However, subtotal esophagectomy, proximal gastrectomy (PG) or even subtotal gastrectomy, when a small upper portion of the stomach can technically be preserved, are alternatives in current clinical practice.
    METHODS: Using a cohort of the PGSAS NEXT trial, consisting of 1909 patients responding to a questionnaire sent to 70 institutions between July 2018 and December 2019, gastrectomy type, reconstruction method, and furthermore the remnant stomach size and the anti-reflux procedures for PG were evaluated.
    RESULTS: TG was the procedure most commonly performed (63.0%), followed by PG (33.4%). Roux-en-Y was preferentially employed following TG irrespective of esophageal tumor invasion, while jejunal pouch was adopted in 8.5% of cases with an abdominal esophageal stump. Esophagogastrostomy was most commonly selected after PG, followed by the double-tract method. The former was preferentially employed for larger remnant stomachs (≧3/4), while being used slightly less often for tumors with as compared to those without esophageal invasion in cases with a remnant stomach 2/3 the size of the original stomach. Application of the double-tract method gradually increased as the remnant stomach size decreased. Anti-reflux procedures following esophagogastrostomy varied markedly.
    CONCLUSIONS: TG is the mainstream and PG remains an alternative in current Japanese clinical practice for proximal gastric cancer. Remnant stomach size and esophageal stump location appear to influence the choice of reconstruction method following PG.
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