PDF(Pubmed)
Abstract：
UNASSIGNED: The current study compared the postoperative quality of life (QOL) between the esophagogastrostomy method (PGEG) and double tract method (PGDT) after proximal gastrectomy using the Postgastretomy Syndrome Assessment Scale (PGSAS)-45.
UNASSIGNED: Among the 2364 patients who received the PGSAS-45 questionnaire, 300 PGEG and 172 PGDT cases responded. The main outcomes measures (MOMs) consisted of seven subscales (SS) covering symptoms, meals (amount and quality), ability to work, dissatisfaction with daily life, physical and mental component summary of the 8-Item Short Form Health Survey (SF-8), and change in body weight, and were compared between PGEG and PGDT.
UNASSIGNED: Overall, PGDT promoted significantly better constipation SS scores (p < 0.05), whereas PGEG tended to promote better body weight (BW) loss% (p < 0.10). A stratified analysis based on the remnant stomach size revealed that among those with a remnant stomach size of 1/2, PGDT had significantly better constipation and dumping SS scores (p < 0.05) and tended to have better working conditions (p < 0.10) compared to PGEG. Even among those with the remnant stomach size of 2/3, PGDT had significantly better diarrhea SS scores, lesser dissatisfaction with symptoms, and better dissatisfaction with daily life SS scores (p < 0.05) and tended to have better constipation SS scores and lesser dissatisfaction with work (p < 0.10) compared to PGEG.
UNASSIGNED: After comparing the QOLs of PGEG and PGDT, the stratified analysis according to remnant stomach sizes of 1/2 and 2/3 revealed that PGDT was relatively superior to PGEG for several MOMs.
UNASSIGNED: Among the 2364 patients who received the PGSAS-45 questionnaire, 300 PGEG and 172 PGDT cases responded. The main outcomes measures (MOMs) consisted of seven subscales (SS) covering symptoms, meals (amount and quality), ability to work, dissatisfaction with daily life, physical and mental component summary of the 8-Item Short Form Health Survey (SF-8), and change in body weight, and were compared between PGEG and PGDT.
UNASSIGNED: Overall, PGDT promoted significantly better constipation SS scores (p < 0.05), whereas PGEG tended to promote better body weight (BW) loss% (p < 0.10). A stratified analysis based on the remnant stomach size revealed that among those with a remnant stomach size of 1/2, PGDT had significantly better constipation and dumping SS scores (p < 0.05) and tended to have better working conditions (p < 0.10) compared to PGEG. Even among those with the remnant stomach size of 2/3, PGDT had significantly better diarrhea SS scores, lesser dissatisfaction with symptoms, and better dissatisfaction with daily life SS scores (p < 0.05) and tended to have better constipation SS scores and lesser dissatisfaction with work (p < 0.10) compared to PGEG.
UNASSIGNED: After comparing the QOLs of PGEG and PGDT, the stratified analysis according to remnant stomach sizes of 1/2 and 2/3 revealed that PGDT was relatively superior to PGEG for several MOMs.
摘要：
■本研究使用胃切除术后综合征评估量表（PGSAS）-45比较了近端胃切除术后食管胃吻合术（PGEG）和双道法（PGDT）的术后生活质量（QOL）。
■在接受PGSAS-45问卷的2364名患者中，300例PGEG和172例PGDT病例反应。主要结果测量(MOMs)包括七个涵盖症状的分量表(SS)，膳食（数量和质量），工作能力,对日常生活的不满，8项简短形式健康调查(SF-8)的身体和心理组成部分摘要，和体重的变化，并对PGEG和PGDT进行了比较。
■总的来说，PGDT促进明显优于便秘SS评分（p<0.05），而PGEG倾向于促进更好的体重(BW)损失%(p<0.10)。根据残胃大小进行的分层分析显示，在残胃大小为1/2的患者中，PGDT的便秘和倾倒SS评分明显更好（p<0.05），并且工作条件更好（p<0.10）。即使在残胃大小为2/3的人群中，PGDT的腹泻SS评分也明显更好，对症状的不满程度较低，与PGEG相比，对日常生活SS评分的不满意度更好（p<0.05），并且倾向于便秘SS评分和对工作的不满意度更低（p<0.10）。
■比较PGEG和PGDT的QOL后，根据1/2和2/3的残胃大小进行的分层分析显示，对于几种MOM，PGDT相对优于PGEG。
■在接受PGSAS-45问卷的2364名患者中，300例PGEG和172例PGDT病例反应。主要结果测量(MOMs)包括七个涵盖症状的分量表(SS)，膳食（数量和质量），工作能力,对日常生活的不满，8项简短形式健康调查(SF-8)的身体和心理组成部分摘要，和体重的变化，并对PGEG和PGDT进行了比较。
■总的来说，PGDT促进明显优于便秘SS评分（p<0.05），而PGEG倾向于促进更好的体重(BW)损失%(p<0.10)。根据残胃大小进行的分层分析显示，在残胃大小为1/2的患者中，PGDT的便秘和倾倒SS评分明显更好（p<0.05），并且工作条件更好（p<0.10）。即使在残胃大小为2/3的人群中，PGDT的腹泻SS评分也明显更好，对症状的不满程度较低，与PGEG相比，对日常生活SS评分的不满意度更好（p<0.05），并且倾向于便秘SS评分和对工作的不满意度更低（p<0.10）。
■比较PGEG和PGDT的QOL后，根据1/2和2/3的残胃大小进行的分层分析显示，对于几种MOM，PGDT相对优于PGEG。
