一部小说,基于杂原子(S,N,P,O)掺杂的碳纳米片(SNPO-CPL)改性铅笔石墨(LPG)已通过碳化独特的杂原子(S,N,P,含O)的新型聚合物,聚(环三磷腈-co-2,5-二氧基-1,4-二噻烷)(PCD),精确筛选多巴胺(DA)。设计的电极,SNPO-CPL-800,具有优化的S百分比,N,P,通过sp2碳链掺杂O,和大量的表面缺陷(从而导致最大数量的催化活性位点的暴露)导致分子通过微孔结构的快速扩散,并促进与电极-电解质界面处的交互式信号传导器中的目标分子的强结合相互作用。设计的SNPO-CPL-800电极对DA监测表现出灵敏和选择性的反应,检测限(LOD)为0.01nM。我们还使用SNPO-CPL-800电极监测市售鸡样品中的DA水平,即使存在干扰物种,从而证明了所设计的电极在实际样品中精确监测DA的有效性。这项研究表明,使用无金属电极为超灵敏的DA监测打开新窗口的潜力很大。
A novel, metal-free electrode based on heteroatom (S, N, P, O)-doped carbon nanoplates (SNPO-CPL) modifying lead pencil graphite (LPG) has been synthesized by carbonizing a unique heteroatom (S, N, P, O)-containing novel polymer, poly(cyclcotriphosphazene-co-2,5-dioxy-1,4-dithiane) (PCD), for precise screening of dopamine (DA). The designed electrode, SNPO-CPL-800, with optimized percentage of S, N, P, O doping through the sp2-carbon chain, and a large number of surface defects (thus leading to a maximum exposition number of catalytic active sites) led to fast molecular diffusion through the micro-porous structure and facilitated strong binding interaction with the targeted molecules in the interactive signaling transducer at the electrode-electrolyte interface. The designed SNPO-CPL-800 electrode exhibited a sensitive and selective response towards DA monitoring, with a limit of detection (LOD) of 0.01 nM. We also monitored DA levels in commercially available chicken samples using the SNPO-CPL-800 electrode even in the presence of interfering species, thus proving the effectiveness of the designed electrode for the precise monitoring of DA in real samples. This research shows there is a strong potential for opening new windows for ultrasensitive DA monitoring with metal-free electrodes.