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Abstract：
This article reports a simple hydrothermal method for synthesizing nickel disulfide (NiS2) on the surface of fluorine-doped tin oxide (FTO) glass, followed by the deposition of 5 nm Au nanoparticles on the electrode surface by physical vapor deposition. This process ensures the uniform distribution of Au nanoparticles on the NiS2 surface to enhance its conductivity. Finally, an Au@NiS2-FTO electrochemical biosensor is obtained for the detection of dopamine (DA). The composite material is characterized using transmission electron microscopy (TEM), UV-Vis spectroscopy, X-ray diffraction, and X-ray photoelectron spectroscopy. The electrochemical properties of the sensor are investigated using cyclic voltammetry (CV), differential pulse voltammetry (DPV), and time current curves in a 0.1 M PBS solution (pH = 7.3). In the detection of DA, Au@NiS2-FTO exhibits a wide linear detection range (0.1~1000 μM), low detection limit (1 nM), and fast response time (0.1 s). After the addition of interfering substances, such as glucose, L-ascorbic acid, uric acid, CaCl2, NaCl, and KCl, the electrode potential remains relatively unchanged, demonstrating its strong anti-interference capability. It also demonstrates strong sensitivity and reproducibility. The obtained Au@NiS2-FTO provides a simple and easy-to-operate example for constructing nanometer catalysts with enzyme-like properties. These results provide a promising method utilizing Au coating to enhance the conductivity of transition metal sulfides.
摘要：
本文报道了一种在氟掺杂氧化锡（FTO）玻璃表面合成二硫化镍（NiS2）的简单水热法，然后通过物理气相沉积在电极表面上沉积5nmAu纳米颗粒。该过程确保Au纳米颗粒在NiS2表面上的均匀分布以增强其导电性。最后,获得了用于检测多巴胺（DA）的Au@NiS2-FTO电化学生物传感器。使用透射电子显微镜（TEM）对复合材料进行表征，紫外-可见光谱,X射线衍射,和X射线光电子能谱。使用循环伏安法（CV）研究了传感器的电化学性质，差分脉冲伏安法（DPV），和0.1MPBS溶液（pH=7.3）中的时间电流曲线。在DA的检测中,Au@NiS2-FTO具有较宽的线性检测范围(0.1~1000μM),低检测限（1nM），和快速的响应时间（0.1秒）。添加干扰物质后，如葡萄糖，L-抗坏血酸,尿酸,CaCl2、NaCl、和KCl,电极电势保持相对不变，展示了其强大的抗干扰能力。它还显示出强的灵敏度和再现性。所获得的Au@NiS2-FTO为构建具有酶样性质的纳米催化剂提供了简单且易于操作的示例。这些结果提供了一种利用Au涂层增强过渡金属硫化物导电性的有前途的方法。
