背景技术常规制造的义齿基托树脂已经使用超过150年。较新的义齿基托树脂可以提供优越的配合,可以根据患者的特点进行定制,但是关于它们的清洁性的文献仍然有限。口腔可以是数千个微生物群的枢纽。无牙患者对全口义齿的维护不仅取决于患者的维护,还取决于所使用的材料,生物膜粘附,和抛光性。
方法:使用Meshmixer3.5版软件(Meshmixer,澳大利亚)。标准镶嵌(STL)文件已导入并发送用于打印(NextDent,荷兰)(第1组),在聚甲基丙烯酸甲酯(PMMA)中研磨(Ivotion,伊沃克拉,Schaan,列支敦士登)(第2组),和蜡研磨(Upcera,中国),接着是飞溅,反拍打,和使用热固化丙烯酸树脂(DPI,印度)(第3组)。使用浮石抛光获得的样品,并使用UV灭菌单元灭菌。然后将样品浸入念珠菌肉汤的悬浮液中。生物膜形成三天后,进行菌落计数并记录为每毫升菌落形成单位(CFU/mL).使用安全义齿清洁片(根特,NewYork),食盐(碘化食盐,塔塔,印度),Clinsodent(ICPA,孟买,印度),和Polident义齿清洁粉(Polident,安大略省,加拿大)。治疗后进行菌落计数,并将数据制成表格。使用SPSS软件进行统计学分析,比较三组义齿清洁剂的效率。统计学意义为0.05。进行了Kolmogorov-Smirnov检验以确认数据的正常性,然后进行单向方差分析(ANOVA)测试,以比较义齿清洁剂去除念珠菌菌落的效率。
结果:与印刷和常规制造的义齿基托树脂相比,研磨的义齿基托树脂显示出明显更低的菌落数。义齿清洁剂在所有组中都显示出很高的功效,最重要的是安全,显示平均差范围为8.114至9.887CFU/mL,其次是Clinsodent,显示平均值为6.699-9.863CFU/mL,紧随其后的是Polident,显示4.964-7.114CFU/mL,其次是食盐,为5.254-8.920CFU/mL。95%置信区间证实有统计学意义。
结论:传统的念珠菌菌落计数最高,然后是快速成型,并且最少使用研磨的义齿基托树脂。用义齿清洁剂治疗后,安全证明几乎完全消灭了殖民地,使其成为最有效的选择。盐表现出最低的效率,紧随其后的是Polident和Clinsodent,最有效的是安全义齿清洁剂。
BACKGROUND: Conventionally fabricated denture base resins have been used for over 150 years. Newer denture base resins can provide a superior fit and may be customized to the patient\'s characteristics, but the literature on their cleansibility remains limited. The oral cavity can be a hub for thousands of microflora. The maintenance of complete dentures by edentulous patients depends not only on the maintenance of the patient but also on the material used, biofilm adherence, and polishability.
METHODS: Cuboid specimens of 10 × 5 × 2 mm were designed using the Meshmixer version 3.5 software (Meshmixer, Australia). The standard tessellation (STL) file was imported and sent for printing (NextDent, Netherlands) (Group 1), milling in polymethyl methacrylate (PMMA) (Ivotion, Ivoclar, Schaan, Liechtenstein) (Group 2), and wax milling (Upcera, China), followed by flasking, counter flasking, and packing using heat-cured acrylic resin (DPI, India) (Group 3). The obtained specimens were polished using pumice and sterilized using a UV sterilization unit. The specimens were then immersed in a suspension of candida broth. After three days of biofilm formation, a colony count was performed and noted as colony-forming units per milliliter (CFU/mL). Specimens were treated using Secure denture cleansing tablets (Ghent, New York), table salt (iodized table salt, Tata, India), Clinsodent (ICPA, Mumbai, India), and Polident denture cleansing powder (Polident, Ontario, Canada). A colony count was done after treatment, and the data were tabulated. Statistical analysis was done using SPSS software to compare the efficiency of denture cleansers in all three groups, and statistical significance was set at 0.05. The Kolmogorov-Smirnov test was done to confirm the normality of the data, followed by a one-way analysis of variance (ANOVA) test to compare the efficiency of denture cleansers on the removal of candida colonies.
RESULTS: Milled denture base resins showed a significantly lower colony count when compared to printed and conventionally fabricated denture base resins. The denture cleansers showed high efficacy in all groups, with the most significant being Secure, which showed a mean difference ranging from 8.114 to 9.887 CFU/mL, followed by Clinsodent, showing a mean of 6.699-9.863 CFU/mL, followed closely by Polident, showing 4.964-7.114 CFU/mL, followed by table salt, being 5.254-8.920 CFU/mL. The 95% confidence interval confirmed statistical significance.
CONCLUSIONS: The highest candida colony count was demonstrated by the conventional, followed by rapid prototyping, and was least with milled denture base resins. Following treatment with denture cleansers, Secure demonstrated almost complete eradication of colonies, making it the most effective option. Salt exhibited the lowest efficiency, followed closely by Polident and Clinsodent, and the most effective was Secure denture cleanser.