OBJECTIVE: Isokinetic knee extensor strength is poorly evaluated in geriatric day hospitals (GDHs), despite its potential functional significance compared to grip strength. This study aimed to investigate age-related effects on absolute and relative isokinetic knee extensor peak torque (KEPT) data in community-dwelling older GDH patients.
METHODS: A total of 472 French GDH patients (179 men and 293 women, aged 75-94 years) participated in this study. Absolute and relative KEPT were measured at six distinct angular velocities between 0.52 and 3.14 rad/s. In addition, comfortable gait speed and grip strength were assessed. Participants were stratified by sex and age using 5-year intervals. One-way ANOVAs were used to examine age-related effects on KEPT values. Multiple linear regression models were employed to investigate the associations between gait speed and both mean KEPT values and grip strength, with separate models conducted on absolute and relative values.
RESULTS: The recruited GDH patients presented lower absolute and relative KEPT values in comparison with established reference values for healthy community-dwelling older individuals, with men being consistently stronger than women. Notably, there was a significant decline in both absolute and relative KEPT values beyond the age of 85 for both sexes. Importantly, the multiple linear regression analyses conducted revealed a significant positive relationship between gait speed and mean KEPT values, surpassing the association with grip strength.
CONCLUSIONS: These findings underscore the clinical importance of assessing isokinetic knee extensor strength in community-dwelling older GDH patients, particularly for tailoring personalized physical activity interventions.

暂无摘要。

OBJECTIVE: To investigate the potential of virtual contrast-enhanced MRI (VCE-MRI) for gross-tumor-volume (GTV) delineation of nasopharyngeal carcinoma (NPC) using multi-institutional data.
METHODS: This study retrospectively retrieved T1-weighted (T1w), T2-weighted (T2w) MRI, gadolinium-based contrast-enhanced MRI (CE-MRI) and planning CT of 348 biopsy-proven NPC patients from three oncology centers. A multimodality-guided synergistic neural network (MMgSN-Net) was trained using 288 patients to leverage complementary features in T1w and T2w MRI for VCE-MRI synthesis, which was independently evaluated using 60 patients. Three board-certified radiation oncologists and two medical physicists participated in clinical evaluations in three aspects: image quality assessment of the synthetic VCE-MRI, VCE-MRI in assisting target volume delineation, and effectiveness of VCE-MRI-based contours in treatment planning. The image quality assessment includes distinguishability between VCE-MRI and CE-MRI, clarity of tumor-to-normal tissue interface and veracity of contrast enhancement in tumor invasion risk areas. Primary tumor delineation and treatment planning were manually performed by radiation oncologists and medical physicists, respectively.
RESULTS: The mean accuracy to distinguish VCE-MRI from CE-MRI was 31.67%; no significant difference was observed in the clarity of tumor-to-normal tissue interface between VCE-MRI and CE-MRI; for the veracity of contrast enhancement in tumor invasion risk areas, an accuracy of 85.8% was obtained. The image quality assessment results suggest that the image quality of VCE-MRI is highly similar to real CE-MRI. The mean dosimetric difference of planning target volumes were less than 1Gy.
CONCLUSIONS: The VCE-MRI is highly promising to replace the use of gadolinium-based CE-MRI in tumor delineation of NPC patients.

UNASSIGNED: Dega osteotomy is becoming more widely used for the treatment of developmental dysplasia of the hip (DDH).
UNASSIGNED: A thorough description of this procedure is needed as many of the technical aspects are not fully defined. Moreover, more follow-up series are also needed to evaluate its outcomes.
UNASSIGNED: In this study, we gave a detailed anatomic description for this procedure and also presented our experience as a retrospective radiographic and case-note study. We examined the clinical and radiographic records of 44 patients (48 hips) with varying degrees of DDH.
UNASSIGNED: The average age of the patients was 2 months and 7 months while the average follow up period was 41 months. Clinical and radiographic assessment including CT with 3D reconstruction to examine the anatomic characteristics of the osteotomy were undertaken. We found that concentric reduction was achieved in 93.7% with excellent clinical and radiographic outcomes. Only 3 cases needed revision of the Dega osteotomy. The re-operation rate was 12.5%. CT scan revealed that the arcuate line was crossed by the osteotomy in the majority of cases. In 20.7% of cases, a bone cut that was intended to be a Dega osteotomy was found to have been inadvertently implemented as another osteotomy variant. However, this bore no significant effect on the outcome.
UNASSIGNED: We found that a well-implemented Dega osteotomy is a reliable tool to cope with the acetabular changes in DDH.

Despite the importance of communication, radiology departments often depend on communication tools that were not created for the unique needs of imaging workflows, leading to frequent radiologist interruptions. The objective of this study was test the hypothesis that a novel asynchronous communication tool for the imaging workflow (RadConnect) reduces the daily average number of synchronous (in-person, telephone) communication requests for radiologists. We conducted a before-after study. Before adoption of RadConnect, technologists used three conventional communication methods to consult radiologists (in-person, telephone, general-purpose enterprise chat (GPEC)). After adoption, participants used RadConnect as a fourth method. Technologists manually recorded every radiologist consult request related to neuro and thorax CT scans in the 40 days before and 40 days after RadConnect adoption. Telephone traffic volume to section beepers was obtained from the hospital telephone system for the same period. The value and usability experiences were collected through an electronic survey and structured interviews. RadConnect adoption resulted in 53% reduction of synchronous (in-person, telephone) consult requests: from 6.1 ± 4.2 per day to 2.9 ± 2.9 (P < 0.001). There was 77% decrease (P < 0.001) in telephone volume to the neuro and thorax beepers, while no significant volume change was noted to the abdomen beeper (control group). Survey responses (46% response rate) and interviews confirmed the positive impact of RadConnect on interruptions. RadConnect significantly reduced radiologists\' telephone interruptions. Study participants valued the role-based interaction and prioritized worklist overview in the survey and interviews. Findings from this study will contribute to a more focused work environment.

BACKGROUND: For a long time, chronic pruritus was considered difficult to treat. Modern therapy options and detailed guidelines have created new opportunities for patients to improve their quality of life. However, due to the complexity of the disease, the need for multimodal treatment remains.
OBJECTIVE: This article aims to investigate whether dermatological rehabilitation offers additional benefits to those affected and whether it should therefore be part of the treatment concept for chronic pruritus.
METHODS: After introduction of the pruritus program of a rehabilitation clinic, a prospective study is presented that focuses on the patient-relevant benefits of therapy. It used standardized questionnaires to record pruritus intensity, the presence of depression, anxiety, itch-related limitations, and quality of life in patients with chronic pruritus before and after rehabilitation.
RESULTS: Of the patients surveyed, 91.7% achieved a patient-relevant benefit through rehabilitation. Pruritus intensity, depression, anxiety, itch-related limitations, and restrictions on quality of life decreased significantly. Almost half of all participating patients had been initially diagnosed more than 10 years ago.
CONCLUSIONS: Dermatological rehabilitation with a multimodal concept for the treatment of chronic pruritus can help affected patients and should be part of the therapy concept. This should be done as early as possible before the disease progresses over a long period of time and makes treatment more difficult.
UNASSIGNED: HINTERGRUND: Chronischer Pruritus galt lange Zeit als schwer therapierbar. Durch moderne Therapieoptionen und eine ausführliche Leitlinie wurden für die Patienten neue Möglichkeiten geschaffen, ihre Lebensqualität zu verbessern. Es bleibt allerdings durch die Komplexität der Erkrankung die Notwendigkeit einer multimodalen Behandlung.
UNASSIGNED: In diesem Beitrag soll untersucht werden, ob eine dermatologische Rehabilitation den Betroffenen einen zusätzlichen Nutzen bietet und somit ein Bestandteil im Therapiekonzept des chronischen Pruritus sein sollte.
METHODS: Nach einem Einblick in das Pruritus-Programm einer Rehabilitationsklinik folgt die Vorstellung einer prospektiven Studie, die den patientenrelevanten Nutzen der Therapie in den Mittelpunkt rückt. Diese erfasste anhand von standardisierten Fragebögen die Pruritusintensität, das Vorliegen von Depression, Angst, Pruritus-bezogene Einschränkungen und Lebensqualität bei Patienten mit chronischem Pruritus vor und nach der Rehabilitation.
UNASSIGNED: Es erreichten 91,7 % der befragten Patienten durch die Rehabilitation einen patientenrelevanten Nutzen. Die Scores für die Pruritusintensität, das Vorliegen von Depression, Angst, Pruritus-bezogenen Einschränkungen und Einschränkungen der Lebensqualität sanken signifikant. Fast die Hälfte aller teilnehmenden Patienten hatte zuvor einen mehr als 10 Jahre dauernden Krankheitsverlauf.
UNASSIGNED: Eine dermatologische Rehabilitation mit einem multimodalen Konzept zur Therapie des chronischen Pruritus kann den betroffenen Patienten helfen und sollte beim Erstellen eines Therapiekonzeptes einen festen Stellenwert haben. Dies soll möglichst frühzeitig geschehen, noch bevor sich die Erkrankung durch einen langen Verlauf aggraviert und dadurch die Therapie erschwert.

暂无摘要。

Entrustable professional activities (EPAs) are the tasks or responsibilities which can be entrusted to a learner competent in that task to allow for unsupervised practice. The concept of EPAs is well documented in medical education literature, but only recently in nursing education. A paucity of literature exists on the application of an EPA framework specifically in nurse anesthesia. Based on the successful application of EPAs in competency-based medical and nursing education, we are of the opinion that this framework may also be utilized in the transition to competency-based education for nurse anesthesia learners. Many certified registered nurse anesthetists clinical preceptors lack training in competency-based education and teaching. The concept of EPAs may assist clinical preceptors in the translation of competencies and performance evaluation of learners. EPAs are defined for the nurse anesthesia clinical education setting. Examples of EPAs specific to nurse anesthesia include anesthesia machine checks, intubation, invasive line placement, regional anesthesia blocks, and preoperative assessment. Criteria of EPAs, barriers to use, and concrete examples are provided. Deliberate use of the EPA framework by clinical preceptors may lead to a more effective evaluation of the learner, thus resulting in purposeful progression to competence.

暂无摘要。

OBJECTIVE: To investigate the best predictor of muscle strength assessed with both Modified Sphygmomanometer Test (MST) methods (bag adaptation and non-adapted) and to provide normative values for these two MST methods for the strength assessment of the trunk, upper, and lower limb muscles.
METHODS: Cross-sectional study.
METHODS: The strength of 42 muscle groups were assessed with the MST in the bag adaptation and non-adapted methods in 120 healthy individuals, 50 % males, divided into three age groups (20-39, 40-59, 60-79) with 40 subjects per group. Stepwise multiple regression analysis was performed to investigate which independent variables (sex, age, and limb dominance) is the best predictor of muscle strength (α = 5 %).
RESULTS: Sex was the best independent predictor for all muscle groups for both MST methods (8.8 % < R2<57.8 %, p < 0.0001), except for the ankle plantar flexors assed with the non-adapted sphygmomanometer, in which age was the best independent predictor (R2 = 25.6 %; p < 0.0001). The normative values of muscle strength were reported for both MST methods considering the subgroups (sex, age, and limb dominance). Ceiling effect was observed when the MST bag adaptation was used to assess some muscles (8.8 %).
CONCLUSIONS: Sex was the best predictor of muscle strength, as commonly found for muscle strength assessment with the dynamometer. The normative values provided have high clinical utility and can be used to interpret results of muscle strength assessment using both MST methods. For the MST in the bag adaptation method, caution is advised for the assessment of some muscles.