chest wall

胸墙
  • 文章类型: Journal Article
    背景:严重的胸部创伤是一种危及生命的疾病,需要迅速的多学科方法和适当的途径来有效恢复。虽然急性发病率和死亡率是众所周知的胸部创伤患者的结果,在手术治疗中幸存的患者的长期生活质量之前尚未得到广泛调查.
    方法:在2016年11月至2023年11月之间,连续32例患者因胸部外伤接受了手术。年龄,性别,合并症,胸部创伤的部位和程度,伤害严重程度评分(ISS),缩写损伤量表(AIS),器官损伤量表(OIS),胸腔内和胸腔外器官受累,损伤机制,外科手术类型,术后并发症,ICU和总住院时间,通过使用EQ-5D-3L量表和数字疼痛评分(NPRS)收集每位患者的即时临床结果和长期生活质量。结果:结果表明,基于AIS的胸外伤患者的EQOL.5D3L没有显着差异(p=0.55),但观察到与ISS相关的显着差异(p=0.000011)。
    结论:ISS与EQOL.5D3L长期生活质量问卷相关,就长期生活质量而言,代表了在严重胸外伤手术治疗中幸存的患者的最佳预后因素。
    BACKGROUND: Major thoracic trauma represents a life-threatening condition, requiring a prompt multidisciplinary approach and appropriate pathways for effective recovery. While acute morbidity and mortality are well-known outcomes in thoracic-traumatized patients, long-term quality of life in patients surviving surgical treatment has not been widely investigated before.
    METHODS: Between November 2016 and November 2023, thirty-two consecutive patients were operated on because of thoracic trauma. Age, sex, comorbidities, location and extent of thoracic trauma, Injury Severity Score (ISS), Abbreviated Injury Scale (AIS), Organ Injury Scale (OIS), intra and extrathoracic organ involvement, mechanism of injury, type of surgical procedure, postoperative complications, ICU and total length of stay, immediate clinical outcomes and long-term quality of life-by using the EQ-5D-3L scale and Numeric Rate Pain Score (NPRS)-were collected for each patient Results: Results indicated no significant difference in EQOL.5D3L among patients with thoracic trauma based on AIS (p = 0.55), but a significant difference was observed in relation to ISS (p = 0.000011).
    CONCLUSIONS: ISS is correlated with the EQOL.5D3L questionnaire on long-term quality of life, representing the best prognostic factor-in terms of long-term quality of life-in patients surviving major thoracic trauma surgical treatment.
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  • 文章类型: Journal Article
    由于这些肿瘤的异质性以及肿瘤位置和范围的变化,胸壁肉瘤很少见,并且其当前的治疗方案多种多样且复杂。它们仅占新诊断癌症的0.04%,其中约45%包括软组织肉瘤。大型队列研究很少,通常集中在一个特定的治疗项目上。因此,我们的目标是为治疗胸壁肉瘤患者的临床医生提供直升机视野,主要集中于软组织肉瘤。本概述包括新辅助系统或放疗的价值,手术切除,胸壁重建的方法,以及后续行动的必要性。如果存在异质性和相对稀有性,我们建议在参考肉瘤中心的多学科肿瘤委员会或肉瘤网络内讨论胸壁软组织肉瘤的治疗决策,以确保个性化。理性决策。专门从事肉瘤手术的外科肿瘤学家至关重要,对于涉及胸腔的广泛切除,我们建议胸外科医师参与。此外,需要专门的医学和放射肿瘤学家以及整形外科医生,以确保最佳的多模态治疗计划,以优化患者的预后。
    Sarcomas of the chest wall are rare and their current treatment regimen is diverse and complex due to the heterogeneity of these tumors as well as the variations in tumor location and extent. They only account for 0.04% of newly diagnosed cancers of whom about 45% comprise soft tissue sarcomas. Larger cohort studies are scarce and often focus on one specific treatment item. We therefore aim to provide helicopter view for clinicians treating patients with sarcomas of the chest wall, focusing mainly on soft tissue sarcomas. This overview includes the value of neoadjuvant systemic or radiotherapy, surgical resection, approaches for thoracic wall reconstruction, and the need for follow-up. Provided the heterogeneity and relative rarity, we recommend that treatment decisions in soft tissue sarcoma of the chest wall are discussed in a multidisciplinary tumor board at a reference sarcoma center or within sarcoma networks to ensure personalized, rational decision making. A surgical oncologist specialized in sarcoma surgery is crucial, and for extensive resections involving the thoracic cavity we recommend involvement of a thoracic surgeon. In addition, a specialized medical- and radiation oncologist as well as a plastic surgeon is required to ensure the best multimodality treatment plan to optimize patient outcome.
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  • 文章类型: Case Reports
    胸壁肿块可能是由从良性到远处转移部位的各种潜在疾病过程引起的。胸壁是食管腺癌(EAC)转移的罕见部位。当出现不典型的食管病理学症状时,可能会出现延迟诊断。晚期EAC发病率高,生存率低。我们的病例显示EAC的罕见且异常表现,由于诊断延迟,结果不佳。
    A chest wall mass can result from a diversity of underlying disease processes ranging from benign to a site of distant metastasis. The chest wall is a rare site for esophageal adenocarcinoma (EAC) metastasis. Delayed diagnosis can occur when presenting symptoms are not typical of esophageal pathology, and advanced-stage EAC has a high morbidity and low survival rates. Our case demonstrates a rare and unusual presentation of EAC with a poor outcome due to delayed diagnosis.
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  • 文章类型: Journal Article
    背景与目的:胸壁缺损重建是一项复杂的手术,旨在恢复创伤后胸部结构的完整性。肿瘤切除,或先天性问题。在这项研究中,对术后并发症进行调查,以改善对这些危重患者的护理。材料与方法:2004年至2023年在纽伦堡Klinikum和EvangelischesWaldkrankenhausSpandau-Berlin进行了胸壁重建的回顾性研究。数据包括患者人口统计,合并症,缺陷病因,手术细节,和使用Clavien-Dindo分类的并发症。结果:在纳入研究的30例患者中,35例胸壁缺损重建术共发生35例并发症。这些并发症分为22例主要病例和13例次要病例。主要并发症在癌症相关缺陷患者中更为常见,在游离皮瓣和带蒂皮瓣手术之间观察到相当大的差异。值得注意的是,使用股前外侧(ALT)皮瓣与股外侧肌表现出希望,在某些情况下表现出更少的并发症。胸壁缺损的重建与大量并发症有关,而与缺损的病因和所使用的特定外科手术无关。有趣的是,游离皮瓣手术的并发症发生率低于带蒂皮瓣。结论:带有股外侧肌的ALT皮瓣在重建领域值得进一步研究。在这个复杂的外科领域,多学科方法和知情的患者讨论至关重要。强调需要持续的研究和技术改进。
    Background and Objectives: Chest wall defect reconstruction is a complex procedure aimed at restoring thoracic structural integrity after trauma, tumor removal, or congenital issues. In this study, postoperative complications were investigated to improve the care of patients with these critical conditions. Materials and Methods: A retrospective study of chest wall reconstructions from 2004 to 2023 was conducted at Klinikum Nürnberg and Evangelisches Waldkrankenhaus Spandau-Berlin. Data included patient demographics, comorbidities, defect etiology, surgery details, and complications using the Clavien-Dindo classification. Results: Among the 30 patients included in the study, a total of 35 complications occurred in 35 thoracic wall defect reconstructions. These complications were classified into 22 major and 13 minor cases. Major complications were more common in patients with cancer-related defects, and considerable variations were observed between free flap and pedicled flap surgeries. Notably, the use of the anterolateral thigh (ALT) flap with vastus lateralis muscle demonstrated promise, exhibiting fewer complications in select cases. The reconstruction of chest wall defects is associated with substantial complications regardless of the etiology of the defect and the particular surgical procedure used. Interestingly, there was a lower complication rate with free flap surgery than with pedicled flaps. Conclusions: The ALT flap with vastus lateralis muscle deserves further research in this field of reconstruction. Multidisciplinary approaches and informed patient discussions are crucial in this complex surgical field, emphasizing the need for ongoing research and technique refinement.
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  • 文章类型: Case Reports
    我们报告了一例电视胸腔镜手术(VATS)后延迟出血的病例,该病例通过经导管动脉栓塞术成功治疗。一名81岁的妇女通过VATS进行了胸膜活检,以治疗肺癌的胸膜播散。术后病程良好,但8天后,她因右腋窝肿胀住院,并被诊断为术后延迟出血。进行纱布压缩,患者出院后未出现血肿加重。然而,4天后,她因肿胀和疼痛迅速恶化而住院。再出血时的胸部计算机断层扫描显示,周围右胸外侧动脉的血肿和外渗增加。病人立即接受紧急血管造影治疗,并进行线圈栓塞。经过这种治疗,患者表现良好,没有出血复发。
    We report a case of delayed bleeding after video-assisted thoracic surgery (VATS) that was successfully treated with transcatheter arterial embolization. An 81-year-old woman underwent a pleural biopsy via VATS for pleural dissemination of lung cancer. The postoperative course was good, but 8 days later she was hospitalized for swelling in the right axilla and was admitted to our hospital with a diagnosis of delayed postoperative hemorrhage. Gauze compression was performed, and the patient was discharged without exacerbation of hematoma. However, 4 days later, she was hospitalized for rapidly worsening swelling and pain. Chest computed tomography at the time of rebleeding showed an increase in the hematoma and extravasation in the peripheral right lateral thoracic artery. The patient was immediately treated with emergency angiography, and coil embolization was performed. After this treatment, the patient has done well and there has been no subsequent recurrence of bleeding.
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  • 文章类型: Case Reports
    胸壁重建是最具挑战性的手术之一,因为缺损包括多个组件,每个组件都需要用相似的组织单独重建。胸壁重建的范围从简单的皮肤覆盖到复杂的骨和或纵隔/心前重建。各种重建方法包括自体以及同种异体技术。自体技术包括有或没有骨的区域或远处皮瓣。而同种异体技术包括放置各种植入材料,如钛板/网,不锈钢网,medpore和生物相容性3D打印模型。我们在这篇文章中进行了广泛切除,旨在完全切除复发性胸壁软骨肉瘤和缺损,包括胸壁的所有组件,包括心前区衬里。重建是通过使用丙烯酸植入物结合自体和异体技术进行的。
    Chest wall reconstruction is among one of the most challenging surgeries because the defect comprises multiple components and each needs to be reconstructed separately with like tissues. Chest wall reconstruction ranges from simple skin cover to complex bony and or mediastinal/precordial reconstruction. Various methods of reconstruction include autologous as well alloplastic techniques. Autologous techniques include regional or distant flaps with or without bone. Whereas alloplastic techniques include the placement of a variety of implant materials like titanium plate/mesh, stainless steel mesh, medpore and biocompatible 3D-printed models. we present this article where extensive resection was performed, aiming to complete removal of recurrent chest wall chondrosarcoma and defect included all components of chest wall including precordial lining. The reconstruction was performed by using combined autologous as well as alloplastic techniques using acrylic implant.
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  • 文章类型: Journal Article
    原发性自发性气胸(PSP)主要影响苗条和高个子年轻男性。探索胸壁结构特征与PSP之间的病因联系对于改进治疗方法至关重要。在这项病例对照研究中,胸外科手术患者的胸部计算机断层扫描(CT)图像,有或没有PSP,使用人工智能进行分析。在Imagenet上使用EfficientNetB3和InceptionV3的卷积神经网络(CNN)模型与迁移学习进行比较。在胸部CT扫描上创建了热图,以增强互操作性,并采用尺度不变特征变换(SIFT)进一步比较图像水平。共选择26例非PSP患者的2,312张CT图像和26例PSP患者的1,122张CT图像。在25例PSP和3例非PSP患者中发现了胸壁尖坑(CAP)(p<0.001)。CNN通过识别CAP的存在,在基于胸壁特征区分PSP和非PSP方面实现了93.47%的测试准确度。热图分析证明了CNN在瞄准上胸壁方面的精确性,准确识别CAP,而不会受到类似结构的不当影响,或不适当地扩大或最小化测试区域。SIFT结果表明,与PSP和非PSP相比,组内平均相似性高10.55%(p<0.001)。总之,在PSP患者中观察到独特的X线胸壁结构,CAP可能是与PSP相关的病因。这项研究强调了AI辅助分析在完善PSP诊断方法和治疗策略方面的潜力。
    Primary spontaneous pneumothorax (PSP) primarily affects slim and tall young males. Exploring the etiological link between chest wall structural characteristics and PSP is crucial for advancing treatment methods. In this case-control study, chest computed tomography (CT) images from patients undergoing thoracic surgery, with or without PSP, were analyzed using Artificial Intelligence. Convolutional Neural Network (CNN) model of EfficientNetB3 and InceptionV3 were used with transfer learning on the Imagenet to compare the images of both groups. A heatmap was created on the chest CT scans to enhance interoperability, and the scale-invariant feature transform (SIFT) was adopted to further compare the image level. A total of 2,312 CT images of 26 non-PSP patients and 1,122 CT images of 26 PSP patients were selected. Chest-wall apex pit (CAP) was found in 25 PSP and three non-PSP patients (p < 0.001). The CNN achieved a testing accuracy of 93.47 % in distinguishing PSP from non-PSP based on chest wall features by identifying the existence of CAP. Heatmap analysis demonstrated CNN\'s precision in targeting the upper chest wall, accurately identifying CAP without undue influence from similar structures, or inappropriately expanding or minimizing the test area. SIFT results indicated a 10.55 % higher mean similarity within the groups compared to between PSP and non-PSP (p < 0.001). In conclusion, distinctive radiographic chest wall configurations were observed in PSP patients, with CAP potentially serving as an etiological factor linked to PSP. This study accentuates the potential of AI-assisted analysis in refining diagnostic approaches and treatment strategies for PSP.
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  • 文章类型: Journal Article
    背景:胸壁肉瘤通过广泛切除和复杂缺损重建来恢复胸壁完整性。这是一项艰难的外科手术,采用多学科方法获得最佳结果,预防矛盾的胸部运动问题并减少并发症。
    目的:我们的目的是描述我们使用聚丙烯网(Marlex®Mesh)结合甲基丙烯酸甲酯和软组织覆盖的胸壁重建的经验。
    方法:在米兰欧洲肿瘤研究所(IEO)接受原发性胸壁肉瘤治疗的53例患者中,意大利,从1998年到2020年,14例使用聚丙烯网进行了胸壁切除和重建,甲基丙烯酸甲酯和背阔肌皮瓣。局部晚期乳腺癌患者,局部晚期肺癌,鳞状细胞癌,其他继发性胸壁恶性肿瘤被排除在研究之外,不同类型的胸壁重建患者也是如此。
    结果:在这项研究中,纳入了14例患有各种原发性胸壁肉瘤的患者(6例男性和8例女性)。平均而言,手术中切除了2根肋骨(范围:1-5),胸壁缺损范围为20至150cm2,平均大小为73cm2。这些患者的平均随访期约为63.80个月。原发性肉瘤手术后低成本和有效的单期胸壁重建。
    BACKGROUND: Chest-wall sarcomas are treated with extensive resections and complex defect reconstruction to restore chest-wall integrity. It is a difficult surgical procedure that incorporates a multidisciplinary approach for the best outcome, preventing paradoxical chest movement issues and reducing complications.
    OBJECTIVE: We aimed to describe our experience of chest-wall reconstruction using polypropylene mesh (Marlex® Mesh) combined with methyl-methacrylate and soft-tissue coverage with a latissimus dorsi flap following sarcoma resection.
    METHODS: Among the 53 patients treated for primary chest-wall sarcomas at the European Institute of Oncology (IEO) in Milan, Italy, from 1998 to 2020, 14 cases underwent chest-wall resection and reconstruction using polypropylene mesh, methyl-methacrylate and the latissimus dorsi flap. Patients with locally advanced breast cancers, locally advanced lung cancers, squamous cell carcinomas, and other secondary chest-wall malignancies were excluded from the study, as were the patients with different types of chest-wall reconstruction.
    RESULTS: In this study, 14 patients (6 men and 8 women) with various primary chest-wall sarcomas were enrolled. On an average, 2 ribs (range: 1-5) were removed during the surgeries, and the chest-wall defects ranged from 20 to 150 cm2 with an average size of 73 cm2. The mean follow-up period for these patients was approximately 63.80 months CONCLUSION: The combination of Marlex® mesh filled with methyl-methacrylate and covered using latissimus dorsi myocutaneous flap provides safe, low-cost and effective single-stage chest-wall reconstruction after surgery for primary sarcomas.
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  • 文章类型: Case Reports
    软组织粘液瘤是通常在近端肢体的肌内成分中发现的良性间质瘤。然而,胸壁软组织粘液瘤很少见。我们报道了一名41岁的软组织粘液瘤妇女的病例,她的左前胸壁上有明显的肿块,已经存在了几年。乳房X光检查显示一个椭圆形,受限制,左乳内上象限的乳腺后脂肪层中的高密度肿块。超声检查发现一个椭圆形,受限制,和低回声肿块,内部回声和多个微囊间隙。还检测到与肿块极点和周围高回声边缘相邻的三角形高回声区域。患者行手术切除,诊断为皮下表现的软组织粘液瘤。
    Soft tissue myxomas are benign mesenchymal neoplasms typically found in the intramuscular components of the proximal extremities. However, soft tissue myxomas in the chest wall are rare. We report the case of a 41-year-old woman with soft tissue myxoma who presented with a slowly growing, palpable lump on her left anterior chest wall that has been present for several years. Mammography revealed an oval, circumscribed, and hyperdense mass in the retromammary fat layer of the upper inner quadrant of the left breast. Ultrasonography revealed an oval, circumscribed, and hypoechoic mass with internal echoes and multiple microcystic spaces. A triangular hyperechoic area adjacent to the pole of the mass and peripheral hyperechoic rim were also detected. The patient underwent surgical excision and was diagnosed with soft tissue myxoma with subcutaneous manifestation.
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  • 文章类型: Journal Article
    背景:儿童肿瘤大切除后的胸壁重建可以用刚性或柔性材料进行。骨水泥成形术通常与“三明治”方法一起使用,即围绕水泥两面的gore-tex网格。
    目的:负载抗生素的单侧gore-tex\“Tartine”甲基丙烯酸甲酯骨水泥成形术是否可以替代双侧“三明治”方法进行胸壁重建?
    方法:包括2011年至2023年在我们医院接受治疗的连续患者。
    结果:在10名接受中位5.6年随访的儿童中,没有与重建相关的手术并发症,功能丧失,感染,术后并发症(包括全球报道的50例刚性重建的荟萃分析为22.7%)和脊柱侧凸(25%).三名患者的胸壁外观不对称。
    结论:“Tartine”骨水泥成形术是一种简单的,用于小儿胸壁重建的低成本技术。它具有良好的耐受性,并检查了胸壁重建的关键要求。
    方法:IV;回顾性病例系列。
    BACKGROUND: Chest wall reconstruction in children after large resection of tumors may be performed with rigid or soft materials. Cementoplasty is commonly used with the \"Sandwich\" method i.e. gore-tex meshes surrounding both faces of the cement.
    OBJECTIVE: Is antibiotic loaded single-side gore-tex \"Tartine\" methyl-methacrylate cementoplasty an interesting alternative to the double-side \"sandwich\" method for chest wall reconstruction?
    METHODS: Consecutive patients who were treated from 2011 to 2023 in our hospital were included.
    RESULTS: Among the ten children treated with a median 5.6 years follow-up, there were no surgical complications related to the reconstruction, loss of function, infections, post operative complications (versus 22.7% in meta-analysis encompassing the 50 rigid reconstructions reported worldwide) nor scoliosis (versus 25%). Three patients have an asymmetric chest wall appearance.
    CONCLUSIONS: \"Tartine\" cementoplasty is a simple, low-cost technique for pediatric chest wall reconstruction. It is well tolerated and checks key demands for chest wall reconstructions.
    METHODS: IV; retrospective case series.
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