Abstract：
BACKGROUND: Chest-wall sarcomas are treated with extensive resections and complex defect reconstruction to restore chest-wall integrity. It is a difficult surgical procedure that incorporates a multidisciplinary approach for the best outcome, preventing paradoxical chest movement issues and reducing complications.
OBJECTIVE: We aimed to describe our experience of chest-wall reconstruction using polypropylene mesh (Marlex® Mesh) combined with methyl-methacrylate and soft-tissue coverage with a latissimus dorsi flap following sarcoma resection.
METHODS: Among the 53 patients treated for primary chest-wall sarcomas at the European Institute of Oncology (IEO) in Milan, Italy, from 1998 to 2020, 14 cases underwent chest-wall resection and reconstruction using polypropylene mesh, methyl-methacrylate and the latissimus dorsi flap. Patients with locally advanced breast cancers, locally advanced lung cancers, squamous cell carcinomas, and other secondary chest-wall malignancies were excluded from the study, as were the patients with different types of chest-wall reconstruction.
RESULTS: In this study, 14 patients (6 men and 8 women) with various primary chest-wall sarcomas were enrolled. On an average, 2 ribs (range: 1-5) were removed during the surgeries, and the chest-wall defects ranged from 20 to 150 cm2 with an average size of 73 cm2. The mean follow-up period for these patients was approximately 63.80 months CONCLUSION: The combination of Marlex® mesh filled with methyl-methacrylate and covered using latissimus dorsi myocutaneous flap provides safe, low-cost and effective single-stage chest-wall reconstruction after surgery for primary sarcomas.
OBJECTIVE: We aimed to describe our experience of chest-wall reconstruction using polypropylene mesh (Marlex® Mesh) combined with methyl-methacrylate and soft-tissue coverage with a latissimus dorsi flap following sarcoma resection.
METHODS: Among the 53 patients treated for primary chest-wall sarcomas at the European Institute of Oncology (IEO) in Milan, Italy, from 1998 to 2020, 14 cases underwent chest-wall resection and reconstruction using polypropylene mesh, methyl-methacrylate and the latissimus dorsi flap. Patients with locally advanced breast cancers, locally advanced lung cancers, squamous cell carcinomas, and other secondary chest-wall malignancies were excluded from the study, as were the patients with different types of chest-wall reconstruction.
RESULTS: In this study, 14 patients (6 men and 8 women) with various primary chest-wall sarcomas were enrolled. On an average, 2 ribs (range: 1-5) were removed during the surgeries, and the chest-wall defects ranged from 20 to 150 cm2 with an average size of 73 cm2. The mean follow-up period for these patients was approximately 63.80 months CONCLUSION: The combination of Marlex® mesh filled with methyl-methacrylate and covered using latissimus dorsi myocutaneous flap provides safe, low-cost and effective single-stage chest-wall reconstruction after surgery for primary sarcomas.
摘要：
背景：胸壁肉瘤通过广泛切除和复杂缺损重建来恢复胸壁完整性。这是一项艰难的外科手术，采用多学科方法获得最佳结果，预防矛盾的胸部运动问题并减少并发症。
目的：我们的目的是描述我们使用聚丙烯网（Marlex®Mesh）结合甲基丙烯酸甲酯和软组织覆盖的胸壁重建的经验。
方法：在米兰欧洲肿瘤研究所（IEO）接受原发性胸壁肉瘤治疗的53例患者中，意大利,从1998年到2020年，14例使用聚丙烯网进行了胸壁切除和重建，甲基丙烯酸甲酯和背阔肌皮瓣。局部晚期乳腺癌患者,局部晚期肺癌，鳞状细胞癌，其他继发性胸壁恶性肿瘤被排除在研究之外，不同类型的胸壁重建患者也是如此。
结果：在这项研究中，纳入了14例患有各种原发性胸壁肉瘤的患者（6例男性和8例女性）。平均而言,手术中切除了2根肋骨（范围：1-5），胸壁缺损范围为20至150cm2，平均大小为73cm2。这些患者的平均随访期约为63.80个月。原发性肉瘤手术后低成本和有效的单期胸壁重建。
目的：我们的目的是描述我们使用聚丙烯网（Marlex®Mesh）结合甲基丙烯酸甲酯和软组织覆盖的胸壁重建的经验。
方法：在米兰欧洲肿瘤研究所（IEO）接受原发性胸壁肉瘤治疗的53例患者中，意大利,从1998年到2020年，14例使用聚丙烯网进行了胸壁切除和重建，甲基丙烯酸甲酯和背阔肌皮瓣。局部晚期乳腺癌患者,局部晚期肺癌，鳞状细胞癌，其他继发性胸壁恶性肿瘤被排除在研究之外，不同类型的胸壁重建患者也是如此。
结果：在这项研究中，纳入了14例患有各种原发性胸壁肉瘤的患者（6例男性和8例女性）。平均而言,手术中切除了2根肋骨（范围：1-5），胸壁缺损范围为20至150cm2，平均大小为73cm2。这些患者的平均随访期约为63.80个月。原发性肉瘤手术后低成本和有效的单期胸壁重建。
