cancer survivor

癌症幸存者
  • 文章类型: Journal Article
    背景:癌症相关疼痛是与功能损害相关的全球健康相关问题,焦虑,抑郁症,降低了生活质量。已提出对患者及其护理人员使用教育干预措施作为克服癌症疼痛的有希望的工具。这项研究的目的是通过标准化的方法学系统修订来总结癌症患者及其护理人员的实际疼痛教育干预措施,并分析其对疼痛的影响。
    方法:通过PubMed进行搜索,WebofScience,Scopus和Cinhal从成立到2022年9月。确定了包括疼痛教育干预措施的随机对照试验。两名评审员对这些研究进行了独立的数据提取和方法学质量评估。
    结果:本研究共纳入7项研究。荟萃分析显示,疼痛教育干预对最严重的疼痛有显著影响;然而,对平均疼痛没有影响。
    结论:针对患者及其照顾者的疼痛教育干预措施可能对癌症相关疼痛产生积极影响。建议每周至少举行三次约一小时的会议。需要进行进一步的研究,并对长期影响进行分析。疼痛教育干预在改善癌症患者疼痛方面显示出积极的结果,无论癌症的病因或程度如何。应进行方法学质量更好的研究,以解决与教育干预措施有关的特定组成部分。
    BACKGROUND: Cancer-related pain is a global health-related problem associated with functional impairment, anxiety, depression, and reduced quality of life. The use of educational interventions for patients and their caregivers has been proposed as a promising tool for overcoming pain in cancer. The aim of this study was to summarize by means of a standardized methodological systematic revision the actual pain education intervention used in cancer patients and their caregivers and to analyze its effects on pain.
    METHODS: A search was conducted through PubMed, Web of Science, Scopus and Cinhal from their inception to September 2022. Randomized controlled trials which included pain education interventions were identified. Two reviewers performed independent data extraction and methodologic quality assessments of these studies.
    RESULTS: A total of seven studies was included in the study. The meta-analysis showed that pain education interventions have a significant effect on the worst pain; however, there was no effect on average pain.
    CONCLUSIONS: Pain education interventions addressed to patients and their caregivers could have positive effects on cancer-related pain. It is recommended that a minimum of three sessions of about one hour\'s duration be held once a week. Further research needs to be carried out and analyzed on the effects over the long term. Pain education interventions show positive results in improving pain in cancer patients regardless of etiology or extent of the cancer. Studies with better methodological quality should be carried out to address specific components related to education interventions.
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  • 文章类型: Journal Article
    背景:这项研究的目的是描述日本膀胱癌手术后患者的健康相关生活质量(HRQOL),并进行日本和美国患者之间的跨文化比较。
    方法:首先,我们使用膀胱癌指数(BCI-Japan)对日本371例患者的HRQOL进行了横断面评估.四组患者的HRQOL(未经膀胱内治疗的天然膀胱,天然膀胱与膀胱内治疗,回肠导管膀胱切除术,和新膀胱切除术)进行评估。其次,我们从原始BCI论文中比较了日本人和美国人(n=315)。在调整了年龄和性别后,分析各BCI亚域评分的差异.
    结果:在日本患者中,膀胱切除合并新膀胱组的尿区功能评分明显较低,与回肠导管膀胱切除术组相比(p<0。01).尽管如此,两组之间的排尿障碍相当。尽管日本和美国患者之间存在明显差异,泌尿和肠道HRQOL几乎没有差异。在四个治疗组中的三个(除了膀胱内治疗的天然膀胱),日本患者比美国人更有可能报告性功能差(p<0.05)。然而,日本患者比美国人更不容易被他们较低的性功能所困扰,与治疗无关(p<0.05)。
    结论:日本膀胱癌治疗后的HRQOL结果与美国相当,除了性功能和性烦恼。BCI可用于膀胱癌患者HRQOL的跨文化评估。
    BACKGROUND: The aim of this study is to characterize health related quality of life (HRQOL) in Japanese patients after bladder cancer surgery and to perform cross-cultural comparison between Japanese and American patients.
    METHODS: Firstly, we cross-sectionally assessed HRQOL of 371 patients in Japan using the Bladder Cancer Index (BCI-Japanese). HRQOL of the four groups of patients (native bladder without intravesical therapy, native bladder with intravesicaltherapy, cystectomy with ileal conduit, and cystectomy with neobladder) were assessed. Secondly, we compared the Japanese with the American cohort (n = 315) from the original BCI paper. After adjusting for age and gender, the differences in each BCI subdomain score was analyzed.
    RESULTS: Among Japanese patients, the urinary domain function score was significantly lower among the cystectomy with neobladder group, compared to the cystectomy with ileal conduit group (p < 0. 01). Despite this, the urinary bother was comparable between the two groups. Although there were apparent differences between Japanese and American patients, there were few differences in Urinary and Bowel HRQOL. In three of the four treatment groups (other than native bladder with intravesical therapy), Japanese patients were more likely than Americans to report poor sexual function (p < 0.05). However, Japanese patients were less likely than Americans to be bothered by their lower sexual function, regardless of treatment (p < 0.05).
    CONCLUSIONS: HRQOL outcomes following treatment of bladder cancer in Japan are comparable to those in the USA, except for sexual functioning and sexual bother. The BCI can be used for cross-cultural assessments of HRQOL in bladder cancer patients.
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  • 文章类型: Journal Article
    本文回顾了癌症生存的当代和包容性定义,包括已完成或继续接受治疗的有或无疾病患者。西班牙医学肿瘤学会(SEOM)在本文中描述了这些患者的需求,并概述了基于癌症发病率估计和患者需求识别的护理模式,能够提供实际行动来实现有效的护理。本综述的目的是确定癌症对幸存者的主要影响,并建立适当的方法来测量这些影响,以及讨论物理管理,心理和社会,职业,金融,以及其他与健康相关的需求。我们建议为参与护理的不同专业人员提供多学科护理模式和培训计划,并强调挑战以及SEOM和医疗保健政策在确保癌症幸存者最佳护理方面的未来作用。
    This article reviews the contemporary and inclusive definition of cancer survivorship, including patients with and without disease who have completed or continue to undergo treatment. The Spanish Society of Medical Oncology (SEOM) describes in this article the needs of these patients and outlines a care model based on an estimation of cancer incidence and identification of patient needs, to enable the provision of practical actions to achieve effective care. The objectives of this review are to identify the main effects of cancer on survivors and to establish appropriate ways of measuring these effects, as well as discussing the management of physical, psychological and social, occupational, financial, and other health-related needs. We suggest a multidisciplinary care model and training programs for the different professionals involved in care, and highlight challenges and the future role of the SEOM and health-care policy in ensuring optimum care of cancer survivors.
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  • 文章类型: Journal Article
    目的:健康的癌症生存涉及患者积极参与预防性健康行为和后续护理。虽然临床医生和患者通常对激活这些行为负有双重责任,将一些临床医生的努力转变为技术和健康教练可能会增强指南的实施。本文报告了幸存者共享医疗行动和反思电子系统(SHARE-S)计划的可接受性,完全虚拟的多成分干预,包括电子推荐,远程提供的健康指导,和自动短信,以增强患者的自我管理并促进健康的生存。
    方法:SHARE-S在单组混合实施-有效性试验研究中进行了评估。将患者从临床团队电子转介给健康教练,进行三个健康自我管理教练电话,并收到短信以加强教练。对21名患者参与者进行了半结构化定性访谈,2名临床医生,和2名健康教练,以确定干预的可接受性(态度,适当性,适用性,便利性,和感知的有效性),并确定计划的重要要素和潜在的行动机制,以指导未来的实施。
    结果:SHARE-S被描述为具有影响力和便利性。非指令,以患者为中心的健康指导和正念练习被认为是最可接受的;短信不太可接受.利益相关者建议增加格式的灵活性,频率,定时,和参与的时间长短,和其他量身定制的教育材料。患者报告了有形的健康行为变化,改善情绪,并提高责任感和自我效能感。
    结论:SHARE-S总体上是一种可接受且潜在有效的干预措施,可以增强幸存者的自我管理和幸福感。对定制内容的更改,定时,和剂量应进行测试,以确定对可接受性和结果的影响。
    OBJECTIVE: Healthy cancer survivorship involves patients\' active engagement with preventative health behaviors and follow-up care. While clinicians and patients have typically held dual responsibility for activating these behaviors, transitioning some clinician effort to technology and health coaches may enhance guideline implementation. This paper reports on the acceptability of the Shared Healthcare Actions & Reflections Electronic systems in survivorship (SHARE-S) program, an entirely virtual multicomponent intervention incorporating e-referrals, remotely-delivered health coaching, and automated text messages to enhance patient self-management and promote healthy survivorship.
    METHODS: SHARE-S was evaluated in single group hybrid implementation-effectiveness pilot study. Patients were e-referred from the clinical team to health coaches for three health self-management coaching calls and received text messages to enhance coaching. Semi-structured qualitative interviews were conducted with 21 patient participants, 2 referring clinicians, and 2 health coaches to determine intervention acceptability (attitudes, appropriateness, suitability, convenience, and perceived effectiveness) and to identify important elements of the program and potential mechanisms of action to guide future implementation.
    RESULTS: SHARE-S was described as impactful and convenient. The nondirective, patient-centered health coaching and mindfulness exercises were deemed most acceptable; text messages were less acceptable. Stakeholders suggested increased flexibility in format, frequency, timing, and length of participation, and additional tailored educational materials. Patients reported tangible health behavior changes, improved mood, and increased accountability and self-efficacy.
    CONCLUSIONS: SHARE-S is overall an acceptable and potentially effective intervention that may enhance survivors\' self-management and well-being. Alterations to tailored content, timing, and dose should be tested to determine impact on acceptability and outcomes.
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  • 文章类型: Journal Article
    随着癌症生存率的提高,关注幸存者的长期生活质量已经变得至关重要,包括性功能。性生活质量和对癌症进展的恐惧往往是未满足的需求,显著影响癌症患者的整体生活质量。在这项研究中,我们调查了罗马尼亚女性癌症患者的这些因素,并强调了这些因素与心理健康和人口统计学变量的关系.
    这项研究包括242名罗马尼亚女性癌症患者,他们完成了评估性功能的问卷(EORTCQLQ-SHQ22)。对癌症进展的恐惧(FoP-Q),抑郁症(PHQ-9),和焦虑(GAD-7)。我们使用描述性的,探索性,和回归分析。
    大约50%的患者报告性交时的性满意度和疼痛受损。性满意度降低,性功能障碍增加,对癌症进展(FCP)的恐惧加剧与抑郁症有关,焦虑,年龄较小,教育水平较低,农村住宅,未婚身份。
    这项研究揭示了性健康之间复杂的相互作用,对癌症进展的恐惧,以及罗马尼亚女性癌症幸存者的心理健康。解决性问题,提供心理教育,促进应对对进步的恐惧,利用跨学科干预措施对改善这些患者的整体生活质量至关重要。这些发现强调了需要考虑癌症幸存者的生理和心理层面的综合护理方法。
    UNASSIGNED: As cancer survival rates increase, it has become crucial to pay attention to the long-term quality of life of survivors, including sexual functioning. The quality of sexual life and fear of cancer progression are often unmet needs, significantly impacting cancer patients\' overall quality of life. In this study, we investigate these factors in Romanian female cancer patients and highlight their relationship with mental health and demographic variables.
    UNASSIGNED: This study included 242 Romanian female cancer patients who completed questionnaires assessing sexual functioning (EORTC QLQ-SHQ22), fear of cancer progression (FoP-Q), depression (PHQ-9), and anxiety (GAD-7). We examined these relationships using descriptive, exploratory, and regression analyses.
    UNASSIGNED: Around 50% of patients reported impairments in sexual satisfaction and pain during sex. Lower sexual satisfaction increased sexual dysfunction, and heightened fear of cancer progression (FCP) were associated with depression, anxiety, younger age, lower education, rural residence, and unmarried status.
    UNASSIGNED: This study reveals a complex interplay between sexual health, fear of cancer progression, and psychological well-being among female cancer survivors in Romania. Addressing sexual concerns, providing psychoeducation, promoting coping with the fear of progression, and utilizing interdisciplinary interventions are essential to improving these patients\' overall quality of life. These findings underscore the need for integrated care approaches that consider both physical and psychological dimensions of cancer survivorship.
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    文章类型: Journal Article
    散步是身体活动(PA)的一种形式,受癌症影响的个体表示强烈的偏好和兴趣,无论疾病或治疗状态。我们开发了一个基于社区的,户外,由同伴主导的受癌症影响的成年人步行计划,称为“走出去”(WIO)。在六个月的时间里,我们无法达到同伴领导(领导行走小组;n=5个自我认同)或参与者(n=0个自我认同;n=3个通过同伴领导招募)的目标.无法招募意味着我们无法提供WIO计划。在本文中,我们反思了文献中显示的有关步行偏好的内容与对本计划缺乏兴趣之间缺乏连贯性。我们描述了人际和个人层面的挑战。受癌症影响的成年人可以从PA中受益匪浅,并渴望户外步行计划,但问题仍然存在:我们如何最好地启动和推广这种类型的体育活动计划?
    Walking is one form of physical activity (PA) individuals affected by cancer have indicated strong preference for and interest in, regardless of disease or treatment status. We developed a community-based, outdoor, peer-led walking program for adults affected by cancer called Walk it Out (WIO). Over the span of six months, we were unable to meet targets for peer-leaders (to lead the walking groups; n = 5 self-identified) or participants (n = 0 self-identified; n = 3 recruited via peer-leaders). This inability to recruit meant that we were not able to offer the WIO program. In this paper, we reflect upon the lack of coherence between what has been shown in the literature regarding preferences for walking and the lack of interest in the present program. We describe challenges at both the interpersonal and individual level. Adults affected by cancer can benefit immensely from PA, and desire outdoor walking programs, but the question remains: how do we best launch and promote this type of physical activity program?
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  • 文章类型: Journal Article
    背景:运动强度(例如,目标心率[HR])是运动处方的基本组成部分,可为癌症幸存者带来健康益处。尽管胸部佩戴的监视器有效,它们在社区和无监督运动环境中的可行性可能具有挑战性。随着可穿戴技术的不断改进,基于消费者的可穿戴传感器可能代表传统监测的可访问替代方案,提供额外的优势。
    目的:这项研究的目的是检查PolarH10胸部监测仪和FitbitInspireHR之间的一致性,以测量随机干预组的乳腺癌幸存者的HR,飞行员演习试验。
    方法:参与者包括随机参加12周有氧运动项目的乳腺癌幸存者(N=14;年龄38-72岁)。这个节目包括三个60分钟,每周中等强度的步行训练,无论是小组或一对一,由认证的运动生理学家协助,并在当地社区健身中心举行。按照最初的设计,运动处方包括在健身中心进行的36次监督训练.然而,由于COVID-19大流行,监督会话的数量取决于参与者是在2020年3月之前还是之后注册。在每次练习期间,通过PolarH10胸部监护仪和手腕佩戴的FitbitInspireHR在5个阶段同时测量HR(以每分钟节拍为单位):运动前休息;热身中点;运动过程中点;冷静下来的中点;和运动后恢复。运动生理学家在每个阶段的中点从每个设备记录参与者的HR。PolarH10和FitbitInspireHR之间的HR一致性使用Lin一致性相关系数(rc)进行评估,CI为95%。Linrc的范围从0到1.00,0表示不一致,1.00表示完全一致。计算相对错误率以检查运动阶段之间的差异。
    结果:可获得样本中200个监督会话的数据(每位参与者的会话:平均值13.33,SD13.7)。到练习阶段,PolarH10监测仪和Fitbit之间的一致性在运动前坐姿休息(rc=0.76,95%CI0.70-0.81)和运动后坐姿恢复(rc=0.89,95%CI0.86-0.92)期间最高,其次是运动的中点(rc=0.63,95%CI0.55-0.70)和降温(rc=0.68,95%CI0.60-0.74)。热身期间的一致性最低(rc=0.39,95%CI0.27-0.49)。相对错误率范围为-3.91%至3.09%,在热身期间最大(相对错误率:平均值-3.91,SD11.92%)。
    结论:Fitbit高估了运动强度峰值时的HR,构成过度膨胀的风险,这对乳腺癌幸存者的健康水平可能不安全。虽然FitbitInspireHR可用于估计运动HR,在考虑参与者安全和数据解释时,需要采取预防措施。
    背景:Clinicaltrials.govNCT03980626;https://clinicaltrials.gov/study/NCT03980626?term=NCT03980626&rank=1.
    BACKGROUND: Exercise intensity (eg, target heart rate [HR]) is a fundamental component of exercise prescription to elicit health benefits in cancer survivors. Despite the validity of chest-worn monitors, their feasibility in community and unsupervised exercise settings may be challenging. As wearable technology continues to improve, consumer-based wearable sensors may represent an accessible alternative to traditional monitoring, offering additional advantages.
    OBJECTIVE: The purpose of this study was to examine the agreement between the Polar H10 chest monitor and Fitbit Inspire HR for HR measurement in breast cancer survivors enrolled in the intervention arm of a randomized, pilot exercise trial.
    METHODS: Participants included breast cancer survivors (N=14; aged 38-72 years) randomized to a 12-week aerobic exercise program. This program consisted of three 60-minute, moderate-intensity walking sessions per week, either in small groups or one-on-one, facilitated by a certified exercise physiologist and held at local community fitness centers. As originally designed, the exercise prescription included 36 supervised sessions at a fitness center. However, due to the COVID-19 pandemic, the number of supervised sessions varied depending on whether participants enrolled before or after March 2020. During each exercise session, HR (in beats per minute) was concurrently measured via a Polar H10 chest monitor and a wrist-worn Fitbit Inspire HR at 5 stages: pre-exercise rest; midpoint of warm-up; midpoint of exercise session; midpoint of cool-down; and postexercise recovery. The exercise physiologist recorded the participant\'s HR from each device at the midpoint of each stage. HR agreement between the Polar H10 and Fitbit Inspire HR was assessed using Lin concordance correlation coefficient (rc) with a 95% CI. Lin rc ranges from 0 to 1.00, with 0 indicating no concordance and 1.00 indicating perfect concordance. Relative error rates were calculated to examine differences across exercise session stages.
    RESULTS: Data were available for 200 supervised sessions across the sample (session per participant: mean 13.33, SD 13.7). By exercise session stage, agreement between the Polar H10 monitor and the Fitbit was highest during pre-exercise seated rest (rc=0.76, 95% CI 0.70-0.81) and postexercise seated recovery (rc=0.89, 95% CI 0.86-0.92), followed by the midpoint of exercise (rc=0.63, 95% CI 0.55-0.70) and cool-down (rc=0.68, 95% CI 0.60-0.74). The agreement was lowest during warm-up (rc=0.39, 95% CI 0.27-0.49). Relative error rates ranged from -3.91% to 3.09% and were greatest during warm-up (relative error rate: mean -3.91, SD 11.92%).
    CONCLUSIONS: The Fitbit overestimated HR during peak exercise intensity, posing risks for overexercising, which may not be safe for breast cancer survivors\' fitness levels. While the Fitbit Inspire HR may be used to estimate exercise HR, precautions are needed when considering participant safety and data interpretation.
    BACKGROUND: Clinicaltrials.gov NCT03980626; https://clinicaltrials.gov/study/NCT03980626?term=NCT03980626&rank=1.
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  • 文章类型: Journal Article
    目的:我们的研究探讨了不同人口统计学亚组之间的癌症护理中断。它还调查了这些“对癌症幸存者的影响”的精神和身体健康。
    方法:汇总横断面调查数据。
    方法:用于监测流行病学和最终结果的健康信息趋势调查,HINTS-SEER.
    方法:n=1234名癌症幸存者参与了研究并完成了调查。
    方法:结果变量是癌症治疗中的治疗中断,心理健康和身体健康观念,年龄,种族,教育,收入,和性取向。
    方法:使用多重插补来解决缺失数据。进行了描述性统计以了解对护理中断的看法。采用偏最小二乘结构方程模型进行数据分析,根据社会人口统计进行了调整。
    结果:COVID-19影响癌症治疗和随访(69.45%),常规癌症筛查(60.70%),和治疗计划(73.58%),尤其是老年患者。它改变了28.03%的参与者与医疗保健提供者(HCP)的互动。老年人经历治疗预约中断的可能性是2.33倍。认为在新冠肺炎期间与医生联系发生改变的人更有可能是老年人(65岁或以上)(OR=3.85,P=0.011),白色(OR>1,P=.002),收入较高(OR=1.81,P=0.002)。癌症治疗和后续医疗预约的变化对患者的健康产生了负面影响(精神:β=-.006,P=.043;身体:β=-.001,P=.006),常规筛查和预防性护理访问(精神:β=-.029,P=.031;身体:β=-.003,P=.008),和癌症治疗计划(精神:β=-.044,P=.024;身体:β=-.021,P=.040)。
    结论:我们的研究结果强调了实施重点干预措施的关键要求,目的是减轻不同人口群体在癌症护理可及性方面的差异。特别是在紧急情况下,以减轻护理中的任何潜在中断。
    OBJECTIVE: Our study explores cancer care disruption among different demographic subgroups. It also investigates these disruptions\' impacts on cancer survivors\' mental and physical well-being.
    METHODS: Pooled cross-sectional survey data.
    METHODS: Health Information Trends Survey for Surveillance Epidemiology and End Results, HINTS-SEER.
    METHODS: n = 1234 cancer survivors participated in the study and completed the survey.
    METHODS: Outcome variables were treatment disruption in cancer care, mental health and physical health perceptions, age, race, education, income, and sexual orientation.
    METHODS: Multiple imputations were used to address missing data. Descriptive statistics were conducted to understand the perceptions of care disruption. Partial least squares structural equation models were employed for data analysis, adjusted for socio-demographics.
    RESULTS: COVID-19 impacted cancer treatment and follow-up appointments (69.45%), routine cancer screening (60.70%), and treatment plans (73.58%), especially among elderly patients. It changed the interactions with health care providers (HCP) for 28.03% of the participants. Older adults were 2.33 times more likely to experience treatment appointment disruptions. People who thought their contact with their doctors changed during COVID-19 were more likely to be older adults (65 or more) (OR = 3.85, P = .011), white (OR >1, P = .002), and with higher income (OR = 1.81, P = .002). The changes to cancer treatment and follow-up medical appointments negatively impacted the well-being of the patients (mental: β = -.006, P = .043; physical: β = -.001, P = .006), routine screening and preventative care visits (mental: β = -.029, P = .031; physical: β = -.003, P = .008), and cancer treatment plans (mental: β = -.044, P = .024; physical: β = -.021, P = .040).
    CONCLUSIONS: Our findings underscore the crucial requirement for implementing focused interventions aimed at alleviating the discrepancies in the accessibility of cancer care across diverse demographic groups, particularly during times of emergency, in order to mitigate any potential disruptions in care.
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  • 文章类型: Journal Article
    超越癌症健康是一个以病人和照顾者为中心的教育外展活动,有一个鼓舞人心的信息和讲座,解决癌症幸存者共同关心的问题。该活动向社区开放。
    Moving Beyond Cancer to Wellness is a patient- and caregiver-focused educational outreach event with an inspirational message and lectures that address common concerns among cancer survivors. This event is open to the communi.
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  • 文章类型: Journal Article
    背景:癌症相关认知障碍(CRCI)是癌症患者在治疗过程中常见的,35%的患者在治疗完成后出现认知障碍。记忆受损,注意,执行功能,和信息处理速度的报告最多,通常会对日常功能和生活质量(QoL)产生负面影响。尽管有大量的报道,这种不良副作用在常见癌症类型中的调查不足,缺乏对CRCI经验的洞察力。
    目的:本定性综合旨在探索与常见癌症的CRCI经验相关的证据。它还旨在了解CRCI在各种癌症类型中的患病率,认知领域,及其对QoL和功能能力的影响。
    方法:对数据库的全面搜索,包括PubMed,美国心理学会PsycINFO,CINAHL,还有Scopus,将进行。共有2名独立审稿人将筛选标题和摘要以供收录,其次是全文筛选。第三名审核人员将解决数据筛选和纳入过程中出现的任何冲突。随后,将使用关键评估技能计划(CASP)工具进行数据提取和质量评估。结果将使用主题分析进行分析。
    结果:本评论是2023年1月资助的博士课程的一部分。审查于2023年6月开始,目前正在进行数据分析。定性合成将探索跨常见癌症的CRCI的经验。纳入的研究预计将报告许多癌症类型,如乳腺癌,前列腺癌,白血病,还有肺癌.包含的研究类型最有可能是访谈,焦点小组,和具有定性成分的调查。
    结论:该方案强调了定性合成的必要性,该方案将探索跨常见癌症类型的CRCI的经验。它将提供对CRCI的生活经验和可能受到不成比例影响的认知领域的宝贵见解。对CRCI的进一步管理干预和临床试验治疗的需求不断增长,对患者体验的定性探索对其发展至关重要。这种定性合成将为未来的发展提供信息,并有助于改善癌症后的QoL。
    DERR1-10.2196/56888。
    BACKGROUND: Cancer-related cognitive impairment (CRCI) is commonly experienced by patients with cancer during treatment, and 35% of patients experience cognitive impairment after treatment completion. Impairments in memory, attention, executive functioning, and information processing speed are most reported and often negatively impact daily functioning and quality of life (QoL). Despite the large scale of reports, this adverse side effect is underinvestigated across common cancer types, and there is a lack of insight into the CRCI experience.
    OBJECTIVE: This qualitative synthesis aims to explore the evidence in relation to the experience of CRCI across common cancers. It also aims to understand the prevalence of CRCI across various cancer types, cognitive domains, and its impact on QoL and functional ability.
    METHODS: A comprehensive search of databases, including PubMed, American Psychological Association PsycINFO, CINAHL, and Scopus, will be conducted. A total of 2 independent reviewers will screen titles and abstracts for inclusion, followed by full-text screening. A third reviewer will resolve any arising conflicts in the process of data screening and inclusion. Subsequently, data extraction and quality assessment using the Critical Appraisal Skills Programme (CASP) tool will be conducted. The results will be analyzed using thematic analysis.
    RESULTS: This review is part of a PhD program funded in January 2023. The review commenced in June 2023, and data analysis is currently in progress. The qualitative synthesis will explore the experiences of CRCI across common cancers. The included studies are expected to report on numerous cancer types such as breast cancer, prostate cancer, leukemia, and lung cancer. The included study types are most likely to be interviews, focus groups, and surveys with qualitative components.
    CONCLUSIONS: This protocol highlights the need for a qualitative synthesis that will explore the experience of CRCI across common cancer types. It will provide valuable insight into the lived experience of CRCI and the cognitive domains that may be disproportionately affected. There is a growing demand for further management interventions and clinically tested treatments of CRCI and the qualitative exploration of patient experience is crucial for their development. This qualitative synthesis will inform future developments and will contribute to improving QoL after cancer.
    UNASSIGNED: DERR1-10.2196/56888.
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